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btbd2a BTB (POZ) domain containing 2a [ Danio rerio (zebrafish) ]

Gene ID: 565970, updated on 27-Mar-2024

Summary

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Official Symbol
btbd2aprovided by ZNC
Official Full Name
BTB (POZ) domain containing 2aprovided by ZNC
Primary source
ZFIN:ZDB-GENE-030829-3
See related
Ensembl:ENSDARG00000042091 AllianceGenome:ZFIN:ZDB-GENE-030829-3
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
btb2l; btbd2; wz8656; si:dkey-110c1.5
Summary
Predicted to be involved in neurogenesis. Predicted to be located in cytoplasm. Predicted to be active in P-body and cytosol. Is expressed in brain; oocyte; and ovary. Orthologous to human BTBD2 (BTB domain containing 2). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
all
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Genomic context

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Location:
chromosome: 22
Exon count:
9
Annotation release Status Assembly Chr Location
106 current GRCz11 (GCF_000002035.6) 22 NC_007133.7 (20159064..20166697, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 22 NC_007133.6 (20134086..20143184, complement)

Chromosome 22 - NC_007133.7Genomic Context describing neighboring genes Neighboring gene eukaryotic translation elongation factor 2a, tandem duplicate 1 Neighboring gene eukaryotic translation elongation factor 2a, tandem duplicate 2 Neighboring gene high mobility group 20B Neighboring gene unc-13 homolog A (C. elegans)

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Identification and isolation of a BTB-POZ-containing gene expressed in oocytes and early embryos of the zebrafish Danio rerio. Smith TH, et al. Genome, 2006 Jul. PMID 16936789
  2. A genetic, deletion, physical, and human homology map of the long fin region on zebrafish linkage group 2. Iovine MK, et al. Genomics, 2002 Jun. PMID 12036288
  3. Single and joint toxic effects of four antibiotics on some metabolic pathways of zebrafish (Danio rerio) larvae. Qiu W, et al. Sci Total Environ, 2020 May 10. PMID 32036144
  4. A proteome map of the zebrafish (Danio rerio) lens reveals similarities between zebrafish and mammalian crystallin expression. Posner M, et al. Mol Vis, 2008 Apr 25. PMID 18449354, Free PMC Article
  5. Comprehensive expression map of transcription regulators in the adult zebrafish telencephalon reveals distinct neurogenic niches. Diotel N, et al. J Comp Neurol, 2015 Jun 1. PMID 25556858, Free PMC Article

See all (10) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by ZFIN

Process Evidence Code Pubs
involved_in neurogenesis IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in P-body IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
is_active_in cytosol IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
BTB/POZ domain-containing protein 2; BTB/POZ domain-containing protein 2a
Names
BTB (POZ) domain containing 2
btbd2l

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001045092.1 → NP_001038557.1  BTB/POZ domain-containing protein 2a

    See identical proteins and their annotated locations for NP_001038557.1

    Status: PROVISIONAL

    Source sequence(s)
    DQ241789
    UniProtKB/TrEMBL
    Q09WH7
    Related
    ENSDARP00000080348.4, ENSDART00000085913.5
    Conserved Domains (4) summary
    smart00225
    Location:188 → 287
    BTB; Broad-Complex, Tramtrack and Bric a brac
    smart00875
    Location:299 → 398
    BACK; BTB And C-terminal Kelch
    pfam00651
    Location:180 → 284
    BTB; BTB/POZ domain
    pfam08005
    Location:446 → 593
    PHR; PHR domain

RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007133.7 Reference GRCz11 Primary Assembly

    Range
    20159064..20166697 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_021469351.1 → XP_021325026.1  BTB/POZ domain-containing protein 2 isoform X2

    UniProtKB/TrEMBL
    A0A8M9PRU4
    Conserved Domains (3) summary
    smart00875
    Location:259 → 358
    BACK; BTB And C-terminal Kelch
    pfam08005
    Location:406 → 553
    PHR; PHR domain
    cl02518
    Location:180 → 247
    BTB; BTB/POZ domain

  2. XM_021469350.1 → XP_021325025.1  BTB/POZ domain-containing protein 2 isoform X1

    UniProtKB/TrEMBL
    A0A8M9PVB6
    Related
    ENSDARP00000156049.1, ENSDART00000188241.1
    Conserved Domains (3) summary
    smart00875
    Location:269 → 368
    BACK; BTB And C-terminal Kelch
    pfam00651
    Location:176 → 257
    BTB; BTB/POZ domain
    pfam08005
    Location:416 → 563
    PHR; PHR domain

  3. XM_021469352.1 → XP_021325027.1  BTB/POZ domain-containing protein 2 isoform X3

    UniProtKB/TrEMBL
    A0A8M9P4A9
    Conserved Domains (3) summary
    smart00875
    Location:81 → 180
    BACK; BTB And C-terminal Kelch
    pfam00651
    Location:1 → 69
    BTB; BTB/POZ domain
    pfam08005
    Location:228 → 375
    PHR; PHR domain

Reference GRCz11 ALT_DRER_TU_1

Genomic

  1. NW_018395103.1 Reference GRCz11 ALT_DRER_TU_1

    Range
    231399..239068 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

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