senp3a SUMO specific peptidase 3a [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: senp3aprovided by ZNC
Official Full Name: SUMO specific peptidase 3aprovided by ZNC
Primary source: ZFIN:ZDB-GENE-030131-2303
See related: Ensembl:ENSDARG00000095538 AllianceGenome:ZFIN:ZDB-GENE-030131-2303
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: fc03g04; wu:fc03g04
Summary: Predicted to enable cysteine-type peptidase activity. Predicted to be involved in protein desumoylation. Predicted to act upstream of or within proteolysis. Predicted to be part of MLL1 complex. Predicted to be active in nucleus. Orthologous to human SENP3 (SUMO specific peptidase 3). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs: all
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Genomic context

Location:: chromosome: 5

Exon count:: 11

Annotation release	Status	Assembly	Chr	Location
106	current	GRCz11 (GCF_000002035.6)	5	NC_007116.7 (24220157..24231164, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	5	NC_007116.6 (23716357..23727339, complement)

Chromosome 5 - NC_007116.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables cysteine-type peptidase activity	IEA Inferred from Electronic Annotation more info
enables deSUMOylase activity	IBA Inferred from Biological aspect of Ancestor more info
enables hydrolase activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in protein desumoylation	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within proteolysis	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in nucleolus	IEA Inferred from Electronic Annotation more info
is_active_in nucleus	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: SUMO1/sentrin/SMT3 specific peptidase 3a; sentrin-specific protease 3a

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001105114.1 → NP_001098584.1 sentrin-specific protease 3a

Status: PROVISIONAL

Source sequence(s)

BX119902

UniProtKB/TrEMBL

A0A8M1NEK6, A2BEN4

Related

ENSDARP00000114111.1, ENSDART00000143492.2

Conserved Domains (1) summary

pfam02902
Location:361 → 533

Peptidase_C48; Ulp1 protease family, C-terminal catalytic domain

RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

NC_007116.7 Reference GRCz11 Primary Assembly

Range

24220157..24231164 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_021476275.1 → XP_021331950.1 SUMO1/sentrin/SMT3 specific peptidase 3a isoform X1

UniProtKB/TrEMBL

A0A8M9QE82

Conserved Domains (1) summary

cl23802
Location:361 → 482

Peptidase_C48; Ulp1 protease family, C-terminal catalytic domain