msl2a MSL complex subunit 2a [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: msl2aprovided by ZNC
Official Full Name: MSL complex subunit 2aprovided by ZNC
Primary source: ZFIN:ZDB-GENE-070912-449
See related: Ensembl:ENSDARG00000038909 AllianceGenome:ZFIN:ZDB-GENE-070912-449
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: msl2s; si:dkey-223d7.5
Summary: Predicted to enable ubiquitin protein ligase activity. Predicted to be involved in histone H4-K16 acetylation and protein ubiquitination. Predicted to be part of MSL complex. Orthologous to human MSL2 (MSL complex subunit 2). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs: all
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Genomic context

Location:: chromosome: 2

Exon count:: 2

Annotation release	Status	Assembly	Chr	Location
106	current	GRCz11 (GCF_000002035.6)	2	NC_007113.7 (25124539..25129414)
105	previous assembly	GRCz10 (GCF_000002035.5)	2	NC_007113.6 (25468905..25473780)

Chromosome 2 - NC_007113.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables metal ion binding	IEA Inferred from Electronic Annotation more info
enables ubiquitin protein ligase activity	IBA Inferred from Biological aspect of Ancestor more info
enables ubiquitin protein ligase activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in protein ubiquitination	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
part_of MSL complex	IBA Inferred from Biological aspect of Ancestor more info
part_of MSL complex	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: E3 ubiquitin-protein ligase MSL2a

Names: male-specific lethal 2 homolog a; male-specific lethal 2-like 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001163298.1 → NP_001156770.1 E3 ubiquitin-protein ligase MSL2a

Status: VALIDATED

Source sequence(s)

CR786576

UniProtKB/TrEMBL

A0A8M1NV03, B0V0X0

Related

ENSDARP00000056800.4, ENSDART00000056801.6

Conserved Domains (2) summary

cd13122
Location:415 → 464

MSL2_CXC; DNA-binding cysteine-rich domain of male-specific lethal 2 and related proteins

pfam16685
Location:42 → 110

zf-RING_10; zinc RING finger of MSL2