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cyc1 cytochrome c-1 [ Danio rerio (zebrafish) ]

Gene ID: 564379, updated on 27-Mar-2024

Summary

Official Symbol
cyc1provided by ZNC
Official Full Name
cytochrome c-1provided by ZNC
Primary source
ZFIN:ZDB-GENE-031105-2
See related
Ensembl:ENSDARG00000038075 AllianceGenome:ZFIN:ZDB-GENE-031105-2
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
fb80h03; sr:nyz104; im:6911272; wu:fb80h03; zgc:123089
Summary
Predicted to enable electron transfer activity; heme binding activity; and metal ion binding activity. Predicted to be involved in mitochondrial electron transport, ubiquinol to cytochrome c. Predicted to be located in mitochondrial inner membrane and respirasome. Predicted to be integral component of membrane. Predicted to be part of mitochondrial respiratory chain complex III. Is expressed in several structures, including adaxial cell; digestive system; eye; midbrain; and musculature system. Human ortholog(s) of this gene implicated in mitochondrial complex III deficiency nuclear type 6. Orthologous to human CYC1 (cytochrome c1). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
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Genomic context

Location:
chromosome: 6
Exon count:
7
Annotation release Status Assembly Chr Location
106 current GRCz11 (GCF_000002035.6) 6 NC_007117.7 (50381572..50390093)
105 previous assembly GRCz10 (GCF_000002035.5) 6 NC_007117.6 (50382353..50390874)

Chromosome 6 - NC_007117.7Genomic Context describing neighboring genes Neighboring gene RALY heterogeneous nuclear ribonucleoprotein Neighboring gene uncharacterized LOC101886784 Neighboring gene ERGIC and golgi 3 Neighboring gene reactive oxygen species modulator 1 Neighboring gene myelocytomatosis oncogene homolog

Genomic regions, transcripts, and products

Expression

  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

General gene information

Markers

Clone Names

  • MGC123089

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables electron transfer activity IEA
Inferred from Electronic Annotation
more info
 
enables heme binding IEA
Inferred from Electronic Annotation
more info
 
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in mitochondrial electron transport, ubiquinol to cytochrome c IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
located_in mitochondrial inner membrane IEA
Inferred from Electronic Annotation
more info
 
part_of mitochondrial respiratory chain complex III IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
 
located_in respirasome IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
cytochrome c1, heme protein, mitochondrial
NP_001032470.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001037393.2NP_001032470.1  cytochrome c1, heme protein, mitochondrial

    See identical proteins and their annotated locations for NP_001032470.1

    Status: VALIDATED

    Source sequence(s)
    BX649289, EH434095, EH477592, EH598125
    UniProtKB/TrEMBL
    A4FVJ3, Q3B7R0
    Related
    ENSDARP00000055503.4, ENSDART00000055504.6
    Conserved Domains (2) summary
    COG2857
    Location:66297
    CYT1; Cytochrome c1 [Energy production and conversion]
    pfam02167
    Location:78296
    Cytochrom_C1; Cytochrome C1 family

RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007117.7 Reference GRCz11 Primary Assembly

    Range
    50381572..50390093
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)