uts1 urotensin 1 [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: uts1provided by ZNC
Official Full Name: urotensin 1provided by ZNC
Primary source: ZFIN:ZDB-GENE-041014-348
See related: Ensembl:ENSDARG00000014927 AllianceGenome:ZFIN:ZDB-GENE-041014-348
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: ucn; UCN1; wu:fq17a01; si:ch211-243j20.4
Summary: Predicted to enable hormone activity. Predicted to be located in extracellular region. Is expressed in several structures, including basal plate midbrain region; gill; nervous system; pectoral fin; and testis. Orthologous to human UCN (urocortin). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 20

Exon count:: 2

Annotation release	Status	Assembly	Chr	Location
106	current	GRCz11 (GCF_000002035.6)	20	NC_007131.7 (38724114..38727396)
105	previous assembly	GRCz10 (GCF_000002035.5)	20	NC_007131.6 (38821597..38824517)

Chromosome 20 - NC_007131.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Results describe the distribution of urotensin I, UIIalpha and UIIbeta mRNAs in different organs and the cellular localization of the three mRNAs in the spinal cord by in situ hybridization (ISH) histochemistry.
Title: Comparative distribution of the mRNAs encoding urotensin I and urotensin II in zebrafish.
U1 localized in the preoptic area, periventricular hypothalamic and tectal regions, and dorsal part of the trigeminal motor nucleus and several nuclei of the dorsal telencephalon.
Title: Localization of corticotropin-releasing factor, urotensin I, and CRF-binding protein gene expression in the brain of the zebrafish, Danio rerio.

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General gene information

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Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables hormone activity	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in extracellular region	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: urocortin; urotensin 1

Names: UI

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001030180.1 → NP_001025351.1 urotensin 1 precursor

Status: PROVISIONAL

Source sequence(s)

BX510372

UniProtKB/TrEMBL

A0A8M1N7B1, Q5TZ50

Related

ENSDARP00000019621.7, ENSDART00000015095.8

Conserved Domains (1) summary

smart00039
Location:97 → 136

CRF; corticotropin-releasing factor

RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

NC_007131.7 Reference GRCz11 Primary Assembly

Range

38724114..38727396

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_005160830.4 → XP_005160887.2 urocortin isoform X1

UniProtKB/TrEMBL

A0A8M2B7S6

Conserved Domains (1) summary

pfam00473
Location:211 → 248

CRF; Corticotropin-releasing factor family