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pbxip1a pre-B-cell leukemia homeobox interacting protein 1a [ Danio rerio (zebrafish) ]

Gene ID: 563463, updated on 27-Mar-2024

Summary

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Official Symbol
pbxip1aprovided by ZNC
Official Full Name
pre-B-cell leukemia homeobox interacting protein 1aprovided by ZNC
Primary source
ZFIN:ZDB-GENE-060503-871
See related
Ensembl:ENSDARG00000071015 AllianceGenome:ZFIN:ZDB-GENE-060503-871
Gene type
protein coding
RefSeq status
MODEL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
id:ibd5036; si:ch211-210h11.11
Summary
Predicted to be involved in regulation of Rho guanyl-nucleotide exchange factor activity. Predicted to be integral component of membrane. Predicted to be active in membrane. Is expressed in mesoderm and somite. Orthologous to human PBXIP1 (PBX homeobox interacting protein 1). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
all
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Genomic context

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See pbxip1a in Genome Data Viewer
Location:
chromosome: 19
Exon count:
11
Annotation release Status Assembly Chr Location
106 current GRCz11 (GCF_000002035.6) 19 NC_007130.7 (7549591..7567239)
105 previous assembly GRCz10 (GCF_000002035.5) 19 NC_007130.6 (7630648..7648308)

Chromosome 19 - NC_007130.7Genomic Context describing neighboring genes Neighboring gene mitochondrial ribosomal protein L9 Neighboring gene limb and CNS expressed 1 like Neighboring gene S100 calcium binding protein A11 Neighboring gene S100 calcium binding protein U

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. A gene expression screen in zebrafish embryogenesis. Kudoh T, et al. Genome Res, 2001 Dec. PMID 11731487
  2. Hematopoietic gene expression profile in zebrafish kidney marrow. Song HD, et al. Proc Natl Acad Sci U S A, 2004 Nov 16. PMID 15520368, Free PMC Article
  3. 15000 unique zebrafish EST clusters and their future use in microarray for profiling gene expression patterns during embryogenesis. Lo J, et al. Genome Res, 2003 Mar. PMID 12618376, Free PMC Article
  4. Evolution of complexity in the zebrafish synapse proteome. Bayés À, et al. Nat Commun, 2017 Mar 2. PMID 28252024, Free PMC Article
  5. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article

See all (6) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by ZFIN

Process Evidence Code Pubs
involved_in regulation of Rho guanyl-nucleotide exchange factor activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in membrane IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
pre-B-cell leukemia transcription factor interacting protein 1-like; pre-B-cell leukemia transcription factor-interacting protein 1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007130.7 Reference GRCz11 Primary Assembly

    Range
    7549591..7567239
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005159476.4 → XP_005159533.1  pre-B-cell leukemia transcription factor-interacting protein 1 isoform X1

    See identical proteins and their annotated locations for XP_005159533.1

    UniProtKB/TrEMBL
    A0A8M2B630
    Conserved Domains (2) summary
    pfam15960
    Location:433 → 561
    DUF4763; Domain of unknown function (DUF4763)
    cl11531
    Location:387 → 463
    DUF904; Protein of unknown function (DUF904)

  2. XM_686823.9 → XP_691915.5  pre-B-cell leukemia transcription factor-interacting protein 1 isoform X3

    UniProtKB/TrEMBL
    A0A8N7UVA5
    Related
    ENSDARP00000115416.1, ENSDART00000138866.3
    Conserved Domains (2) summary
    pfam15960
    Location:425 → 553
    DUF4763; Domain of unknown function (DUF4763)
    cl11531
    Location:379 → 455
    DUF904; Protein of unknown function (DUF904)

  3. XM_005159477.4 → XP_005159534.1  pre-B-cell leukemia transcription factor-interacting protein 1 isoform X2

    UniProtKB/TrEMBL
    A0A8M2B628, F1RDW1
    Related
    ENSDARP00000099035.2, ENSDART00000115058.4
    Conserved Domains (2) summary
    pfam15960
    Location:427 → 555
    DUF4763; Domain of unknown function (DUF4763)
    cl11531
    Location:381 → 457
    DUF904; Protein of unknown function (DUF904)
Nucleotide Protein Strain
Heading Accession and Version

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