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DAD1P1 defender against cell death 1 pseudogene 1 [ Homo sapiens (human) ]

Gene ID: 56286, updated on 10-Oct-2023

Summary

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Official Symbol
DAD1P1provided by HGNC
Official Full Name
defender against cell death 1 pseudogene 1provided by HGNC
Primary source
HGNC:HGNC:18295
See related
MIM:609860; AllianceGenome:HGNC:18295
Gene type
pseudo
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
DADR; DAD1L
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Genomic context

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Location:
12p12.1
Annotation release Status Assembly Chr Location
RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 12 NC_000012.12 (24917702..24918384, complement)
RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 12 NC_060936.1 (24787752..24788434, complement)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 12 NC_000012.11 (25070636..25071318, complement)

Chromosome 12 - NC_000012.12Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC105369699 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 6102 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 6103 Neighboring gene branched chain amino acid transaminase 1 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 4291 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 6104 Neighboring gene uncharacterized LOC124902898 Neighboring gene H3K27ac hESC enhancer GRCh37_chr12:25055463-25055964 Neighboring gene NANOG-H3K4me1 hESC enhancer GRCh37_chr12:25057459-25058181 Neighboring gene Sharpr-MPRA regulatory region 2351 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr12:25078354-25078971 Neighboring gene H3K27ac hESC enhancer GRCh37_chr12:25080207-25080822 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 6105 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 4292 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 6106 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 6107 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 6108 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 6109 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 6110 Neighboring gene uncharacterized LOC107984475 Neighboring gene brain protein I3 pseudogene 2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Role of gain of 12p in germ cell tumour development. Looijenga LH, et al. APMIS, 2003 Jan. PMID 12752258
  2. A novel human processed gene, DAD-R, maps to 12p12 and is expressed in several organs. Kuittinen T, et al. FEBS Lett, 2000 May 12. PMID 10812081
  3. Coamplification of DAD-R, SOX5, and EKI1 in human testicular seminomas, with specific overexpression of DAD-R, correlates with reduced levels of apoptosis and earlier clinical manifestation. Zafarana G, et al. Cancer Res, 2002 Mar 15. PMID 11912161

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. DAD-R implicated as a candidate gene responsible in part for the pathological effects in human testicular seminomas that result from gain of chromosome 12p sequences.
    Title: Coamplification of DAD-R, SOX5, and EKI1 in human testicular seminomas, with specific overexpression of DAD-R, correlates with reduced levels of apoptosis and earlier clinical manifestation.
Submit: New GeneRIF Correction

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

Variation

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See studies and variants in dbVar

See Variation Viewer (GRCh37.p13)

See Variation Viewer (GRCh38)

General gene information

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Other Names

  • DAD1-related

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_027931.1 

    Range
    101..783
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000012.12 Reference GRCh38.p14 Primary Assembly

    Range
    24917702..24918384 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060936.1 Alternate T2T-CHM13v2.0

    Range
    24787752..24788434 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NR_024064.1: Suppressed sequence

    Description
    NR_024064.1: This RefSeq was permanently suppressed because it is now thought that this gene is a pseudogene.
Nucleotide Protein
Heading Accession and Version

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