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zmiz1a zinc finger, MIZ-type containing 1a [ Danio rerio (zebrafish) ]

Gene ID: 561061, updated on 11-Apr-2024

Summary

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Official Symbol
zmiz1aprovided by ZNC
Official Full Name
zinc finger, MIZ-type containing 1aprovided by ZNC
Primary source
ZFIN:ZDB-GENE-080220-27
See related
Ensembl:ENSDARG00000074502 AllianceGenome:ZFIN:ZDB-GENE-080220-27
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
zmiz1; fb80e10; wu:fb80e10; zgc:175159
Summary
Predicted to enable nuclear receptor coactivator activity. Predicted to be involved in epigenetic maintenance of chromatin in transcription-competent conformation and regulation of transcription by RNA polymerase II. Orthologous to human ZMIZ1 (zinc finger MIZ-type containing 1). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 13
Exon count:
29
Annotation release Status Assembly Chr Location
106 current GRCz11 (GCF_000002035.6) 13 NC_007124.7 (30321401..30570859)
105 previous assembly GRCz10 (GCF_000002035.5) 13 NC_007124.6 (30190943..30440409)

Chromosome 13 - NC_007124.7Genomic Context describing neighboring genes Neighboring gene pyroglutamylated RFamide peptide receptor a Neighboring gene ribosomal protein S24 Neighboring gene zinc finger, CCHC domain containing 24 Neighboring gene peptidylprolyl isomerase Fa

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. DNA methylation and gene expression alterations in zebrafish early-life stages exposed to the antibacterial agent triclosan. Falisse E, et al. Environ Pollut, 2018 Dec. PMID 30408875
  2. zmiz1a zebrafish mutants have defective erythropoiesis, altered expression of autophagy genes, and a deficient response to vitamin D. Castillo-Castellanos F, et al. Life Sci, 2021 Nov 1. PMID 34453946
  3. Assignment of Functional Relevance to Genes at Type 2 Diabetes-Associated Loci Through Investigation of β-Cell Mass Deficits. O'Hare EA, et al. Mol Endocrinol, 2016 Apr. PMID 26963759, Free PMC Article
  4. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

See all (6) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. zmiz1a zebrafish mutants have defective erythropoiesis, altered expression of autophagy genes, and a deficient response to vitamin D.
    Title: zmiz1a zebrafish mutants have defective erythropoiesis, altered expression of autophagy genes, and a deficient response to vitamin D.
Submit: New GeneRIF Correction

General gene information

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Markers

Homology

Clone Names

  • MGC175159

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables SUMO ligase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
enables nuclear receptor coactivator activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in protein sumoylation IBA
Inferred from Biological aspect of Ancestor
more info
  
acts_upstream_of_or_within regulation of hemopoiesis IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
part_of chromatin IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
zinc finger MIZ domain-containing protein 1; zinc finger MIZ domain-containing protein 1a
Names
PIAS-like protein hZimp10
zinc finger, MIZ-type containing 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001113339.1 → NP_001106810.1  zinc finger MIZ domain-containing protein 1a

    See identical proteins and their annotated locations for NP_001106810.1

    Status: PROVISIONAL

    Source sequence(s)
    BC155843
    UniProtKB/TrEMBL
    A9JRY4
    Related
    ENSDARP00000097539.3, ENSDART00000110884.4
    Conserved Domains (2) summary
    pfam02891
    Location:694 → 742
    zf-MIZ; MIZ/SP-RING zinc finger
    pfam04487
    Location:280 → 407
    CITED; CITED

RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007124.7 Reference GRCz11 Primary Assembly

    Range
    30321401..30570859
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_009307322.3 → XP_009305597.1  zinc finger MIZ domain-containing protein 1 isoform X2

    UniProtKB/TrEMBL
    A0A8M3BEN7
    Conserved Domains (2) summary
    pfam02891
    Location:750 → 798
    zf-MIZ; MIZ/SP-RING zinc finger
    pfam04487
    Location:336 → 463
    CITED; CITED

  2. XM_005156853.4 → XP_005156910.1  zinc finger MIZ domain-containing protein 1 isoform X1

    See identical proteins and their annotated locations for XP_005156910.1

    UniProtKB/TrEMBL
    A0A8M2B372
    Conserved Domains (2) summary
    pfam02891
    Location:750 → 798
    zf-MIZ; MIZ/SP-RING zinc finger
    pfam04487
    Location:336 → 463
    CITED; CITED

  3. XM_005156855.4 → XP_005156912.1  zinc finger MIZ domain-containing protein 1 isoform X4

    UniProtKB/TrEMBL
    A0A8M2B3N1
    Conserved Domains (2) summary
    pfam02891
    Location:738 → 786
    zf-MIZ; MIZ/SP-RING zinc finger
    pfam04487
    Location:324 → 451
    CITED; CITED

  4. XM_005156854.4 → XP_005156911.1  zinc finger MIZ domain-containing protein 1 isoform X3

    UniProtKB/TrEMBL
    A0A8M2B3T1
    Conserved Domains (2) summary
    pfam02891
    Location:738 → 786
    zf-MIZ; MIZ/SP-RING zinc finger
    pfam04487
    Location:324 → 451
    CITED; CITED

  5. XM_009307325.3 → XP_009305600.1  zinc finger MIZ domain-containing protein 1 isoform X5

    See identical proteins and their annotated locations for XP_009305600.1

    UniProtKB/TrEMBL
    A0A8M3B818
    Conserved Domains (2) summary
    pfam02891
    Location:607 → 655
    zf-MIZ; MIZ/SP-RING zinc finger
    pfam04487
    Location:193 → 320
    CITED; CITED

  6. XM_009307324.3 → XP_009305599.1  zinc finger MIZ domain-containing protein 1 isoform X5

    See identical proteins and their annotated locations for XP_009305599.1

    UniProtKB/TrEMBL
    A0A8M3B818
    Conserved Domains (2) summary
    pfam02891
    Location:607 → 655
    zf-MIZ; MIZ/SP-RING zinc finger
    pfam04487
    Location:193 → 320
    CITED; CITED
Nucleotide Protein Strain
Heading Accession and Version

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