U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

casz1 castor zinc finger 1 [ Danio rerio (zebrafish) ]

Gene ID: 559053, updated on 27-Mar-2024

Summary

Go to the top of the page Help
Official Symbol
casz1provided by ZNC
Official Full Name
castor zinc finger 1provided by ZNC
Primary source
ZFIN:ZDB-GENE-060130-108
See related
Ensembl:ENSDARG00000037030 AllianceGenome:ZFIN:ZDB-GENE-060130-108
Gene type
protein coding
RefSeq status
MODEL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
sb:eu580; wu:fk85f10
Summary
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Predicted to be involved in positive regulation of transcription by RNA polymerase II and regulation of neuron differentiation. Predicted to act upstream of or within regulation of transcription, DNA-templated. Predicted to be active in nucleus. Is expressed in several structures, including adaxial cell; cardiovascular system; hindbrain neural plate; musculature system; and nervous system. Orthologous to human CASZ1 (castor zinc finger 1). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
human mouse all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See casz1 in Genome Data Viewer
Location:
chromosome: 23
Exon count:
22
Annotation release Status Assembly Chr Location
106 current GRCz11 (GCF_000002035.6) 23 NC_007134.7 (28956258..29065553, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 23 NC_007134.6 (29029717..29139003, complement)

Chromosome 23 - NC_007134.7Genomic Context describing neighboring genes Neighboring gene peroxisomal biogenesis factor 14 Neighboring gene DNA fragmentation factor, alpha polypeptide Neighboring gene si:dkey-246i21.1 Neighboring gene si:ch211-129o18.4 Neighboring gene TAR DNA binding protein a

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Expression

Go to the top of the page Help
  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. In vivo protein trapping produces a functional expression codex of the vertebrate proteome. Clark KJ, et al. Nat Methods, 2011 Jun. PMID 21552255, Free PMC Article
  2. A Toolbox for Efficient Proximity-Dependent Biotinylation in Zebrafish Embryos. Rosenthal SM, et al. Mol Cell Proteomics, 2021. PMID 34332124, Free PMC Article
  3. 15000 unique zebrafish EST clusters and their future use in microarray for profiling gene expression patterns during embryogenesis. Lo J, et al. Genome Res, 2003 Mar. PMID 12618376, Free PMC Article
  4. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
  5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

See all (6) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

Go to the top of the page Help
Products Interactant Other Gene Complex Source Pubs Description

General gene information

Go to the top of the page Help

Markers

Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
Inferred from Biological aspect of Ancestor
more info
  
enables RNA polymerase II transcription regulatory region sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in positive regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
  
acts_upstream_of_or_within regulation of DNA-templated transcription IEA
Inferred from Electronic Annotation
more info
  
involved_in regulation of neuron differentiation IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

Go to the top of the page Help
Preferred Names
zinc finger protein castor homolog 1

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007134.7 Reference GRCz11 Primary Assembly

    Range
    28956258..29065553 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005162285.4 → XP_005162342.1  zinc finger protein castor homolog 1 isoform X3

    UniProtKB/TrEMBL
    A0A8M2B956
    Conserved Domains (1) summary
    pfam06752
    Location:796 → 897
    E_Pc_C; Enhancer of Polycomb C-terminus

  2. XM_021469993.1 → XP_021325668.1  zinc finger protein castor homolog 1 isoform X5

    UniProtKB/TrEMBL
    A0A8M9PFJ4
    Conserved Domains (1) summary
    cl26464
    Location:790 → 975
    Atrophin-1; Atrophin-1 family

  3. XM_021469994.1 → XP_021325669.1  zinc finger protein castor homolog 1 isoform X6

    UniProtKB/TrEMBL
    A0A8M9PL89
    Related
    ENSDARP00000117224.1, ENSDART00000148257.2
    Conserved Domains (1) summary
    cl26464
    Location:812 → 997
    Atrophin-1; Atrophin-1 family

  4. XM_009296966.3 → XP_009295241.1  zinc finger protein castor homolog 1 isoform X1

    UniProtKB/TrEMBL
    A0A8M3B6A1
    Conserved Domains (1) summary
    pfam06752
    Location:813 → 914
    E_Pc_C; Enhancer of Polycomb C-terminus

  5. XM_005162286.4 → XP_005162343.1  zinc finger protein castor homolog 1 isoform X4

    UniProtKB/TrEMBL
    A0A8M2B961
    Conserved Domains (1) summary
    pfam06752
    Location:792 → 893
    E_Pc_C; Enhancer of Polycomb C-terminus

  6. XM_005162284.4 → XP_005162341.1  zinc finger protein castor homolog 1 isoform X2

    UniProtKB/TrEMBL
    A0A8M2B9I3
    Conserved Domains (1) summary
    pfam06752
    Location:802 → 903
    E_Pc_C; Enhancer of Polycomb C-terminus

  7. XM_021469995.1 → XP_021325670.1  zinc finger protein castor homolog 1 isoform X7

    UniProtKB/TrEMBL
    A0A8M9PWX4
    Conserved Domains (1) summary
    pfam06752
    Location:813 → 914
    E_Pc_C; Enhancer of Polycomb C-terminus
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases
Research Materials
Tools
Miscellaneous