creb3l3a cAMP responsive element binding protein 3-like 3a [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: creb3l3aprovided by ZNC
Official Full Name: cAMP responsive element binding protein 3-like 3aprovided by ZNC
Primary source: ZFIN:ZDB-GENE-030131-4298
See related: Ensembl:ENSDARG00000056226 AllianceGenome:ZFIN:ZDB-GENE-030131-4298
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: creb3l3; fc88h05; creb3l3b; wu:fc88h05; zgc:112279; si:dkey-110c1.2
Summary: Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to act upstream of or within endoplasmic reticulum unfolded protein response and positive regulation of transcription by RNA polymerase II. Predicted to be located in endoplasmic reticulum membrane. Predicted to be integral component of membrane. Predicted to be active in nucleus. Is expressed in digestive system; intestinal bulb; liver; and yolk syncytial layer. Orthologous to human CREB3L3 (cAMP responsive element binding protein 3 like 3). [provided by Alliance of Genome Resources, Apr 2022]
Annotation information: Annotation category: partial on reference assembly
Orthologs: all
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Genomic context

Location:: chromosome: 22

Exon count:: 10

Annotation release	Status	Assembly	Chr	Location
106	current	GRCz11 (GCF_000002035.6)	22	NC_007133.7 (20113273..20126170, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	22	NC_007133.6 (20088295..20101192, complement)

Chromosome 22 - NC_007133.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

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General gene information

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Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables DNA binding	IEA Inferred from Electronic Annotation more info
enables DNA-binding transcription factor activity	IEA Inferred from Electronic Annotation more info
enables DNA-binding transcription factor activity, RNA polymerase II-specific	IBA Inferred from Biological aspect of Ancestor more info
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within regulation of DNA-templated transcription	IEA Inferred from Electronic Annotation more info
involved_in regulation of transcription by RNA polymerase II	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
located_in endoplasmic reticulum	IEA Inferred from Electronic Annotation more info
located_in endoplasmic reticulum membrane	IEA Inferred from Electronic Annotation more info
located_in membrane	IEA Inferred from Electronic Annotation more info
is_active_in nucleus	IBA Inferred from Biological aspect of Ancestor more info
located_in nucleus	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: cyclic AMP-responsive element-binding protein 3-like protein 3-A

Names: cAMP responsive element binding protein 3-like 3; cAMP-responsive element-binding protein 3-like protein 3-A; cAMP-responsive element-binding protein 3-like protein 3-B; cyclic AMP-responsive element-binding protein 3-like protein 3-B

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001020673.2 → NP_001018509.2 cyclic AMP-responsive element-binding protein 3-like protein 3-A

Status: VALIDATED

Source sequence(s)

BX005203

UniProtKB/Swiss-Prot

Q1LYG4

Related

ENSDARP00000113661.1, ENSDART00000138688.2