amacr alpha-methylacyl-CoA racemase [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: amacrprovided by ZNC
Official Full Name: alpha-methylacyl-CoA racemaseprovided by ZNC
Primary source: ZFIN:ZDB-GENE-050522-484
See related: Ensembl:ENSDARG00000057435 AllianceGenome:ZFIN:ZDB-GENE-050522-484
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: c1qtnf3; zgc:110704
Summary: Predicted to enable alpha-methylacyl-CoA racemase activity. Predicted to be involved in bile acid metabolic process. Predicted to be active in mitochondrion. Human ortholog(s) of this gene implicated in alpha-methylacyl-CoA racemase deficiency; congenital bile acid synthesis defect 4; and urinary bladder cancer. Orthologous to human AMACR (alpha-methylacyl-CoA racemase). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 21

Exon count:: 6

Annotation release	Status	Assembly	Chr	Location
106	current	GRCz11 (GCF_000002035.6)	21	NC_007132.7 (19418597..19441613)
105	previous assembly	GRCz10 (GCF_000002035.5)	21	NC_007132.6 (19381961..19404977)

Chromosome 21 - NC_007132.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables alpha-methylacyl-CoA racemase activity	IBA Inferred from Biological aspect of Ancestor more info
enables alpha-methylacyl-CoA racemase activity	IEA Inferred from Electronic Annotation more info
enables catalytic activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in bile acid metabolic process	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
is_active_in cellular_component	ND No biological Data available more info
is_active_in mitochondrion	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: alpha-methylacyl-CoA racemase

Names: C1q and tumor necrosis factor related protein 3

NP_001018462.1

EC 5.1.99.4

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001020626.1 → NP_001018462.1 alpha-methylacyl-CoA racemase

See identical proteins and their annotated locations for NP_001018462.1

Status: PROVISIONAL

Source sequence(s)

BC095377

UniProtKB/TrEMBL

Q503C9

Related

ENSDARP00000074560.4, ENSDART00000080110.5

Conserved Domains (1) summary

COG1804
Location:3 → 373

CaiB; Crotonobetainyl-CoA:carnitine CoA-transferase CaiB and related acyl-CoA transferases [Lipid transport and metabolism]