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trit1 tRNA isopentenyltransferase 1 [ Danio rerio (zebrafish) ]

Gene ID: 553523, updated on 27-Mar-2024

Summary

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Official Symbol
trit1provided by ZNC
Official Full Name
tRNA isopentenyltransferase 1provided by ZNC
Primary source
ZFIN:ZDB-GENE-060503-297
See related
Ensembl:ENSDARG00000032876 AllianceGenome:ZFIN:ZDB-GENE-060503-297
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
si:ch211-194e15.1
Summary
Predicted to enable tRNA dimethylallyltransferase activity. Predicted to be involved in tRNA modification. Predicted to act upstream of or within tRNA processing. Predicted to be located in cytoplasm. Predicted to be active in mitochondrion. Human ortholog(s) of this gene implicated in combined oxidative phosphorylation deficiency 35. Orthologous to human TRIT1 (tRNA isopentenyltransferase 1). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 19
Exon count:
12
Annotation release Status Assembly Chr Location
106 current GRCz11 (GCF_000002035.6) 19 NC_007130.7 (30722764..30800077, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 19 NC_007130.6 (31135454..31212769, complement)

Chromosome 19 - NC_007130.7Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC110438138 Neighboring gene family with sequence similarity 49 member A, like Neighboring gene MYCL proto-oncogene, bHLH transcription factor b Neighboring gene MFSD2 lysolipid transporter A, lysophospholipid b

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Evolutionary and Expression Analyses Show Co-option of khdrbs Genes for Origin of Vertebrate Brain. Wang S, et al. Front Genet, 2017. PMID 29354154, Free PMC Article
  2. Comprehensive expression map of transcription regulators in the adult zebrafish telencephalon reveals distinct neurogenic niches. Diotel N, et al. J Comp Neurol, 2015 Jun 1. PMID 25556858, Free PMC Article
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article
  5. Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database. Pasquier J, et al. BMC Genomics, 2016 May 18. PMID 27189481, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
  
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
enables nucleotide binding IEA
Inferred from Electronic Annotation
more info
  
enables tRNA dimethylallyltransferase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables tRNA dimethylallyltransferase activity IEA
Inferred from Electronic Annotation
more info
  
enables transferase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in tRNA modification IBA
Inferred from Biological aspect of Ancestor
more info
  
acts_upstream_of_or_within tRNA processing IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
is_active_in mitochondrion IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
tRNA dimethylallyltransferase; tRNA dimethylallyltransferase, mitochondrial
NP_001038239.1
XP_021323735.1
XP_021323736.1
XP_021323737.1
XP_021323738.1
XP_021323739.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001044774.1 → NP_001038239.1  tRNA dimethylallyltransferase

    Status: PROVISIONAL

    Source sequence(s)
    BX547927
    UniProtKB/TrEMBL
    A0A8M1N9A5, F1Q4Z4, Q1LWL7
    Related
    ENSDARP00000104694.2, ENSDART00000128560.4
    Conserved Domains (2) summary
    PLN02748
    Location:9 → 424
    PLN02748; tRNA dimethylallyltransferase
    PRK00091
    Location:13 → 327
    miaA; tRNA delta(2)-isopentenylpyrophosphate transferase; Reviewed

RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007130.7 Reference GRCz11 Primary Assembly

    Range
    30722764..30800077 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_021468060.1 → XP_021323735.1  tRNA dimethylallyltransferase, mitochondrial isoform X1

    UniProtKB/TrEMBL
    A0A8M9PRJ0
    Conserved Domains (2) summary
    pfam12171
    Location:304 → 328
    zf-C2H2_jaz; Zinc-finger double-stranded RNA-binding
    cl21455
    Location:13 → 242
    P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases

  2. XM_021468064.1 → XP_021323739.1  tRNA dimethylallyltransferase, mitochondrial isoform X4

    UniProtKB/TrEMBL
    A0A8M9PGE6
    Conserved Domains (2) summary
    pfam01715
    Location:26 → 141
    IPPT; IPP transferase
    pfam12171
    Location:203 → 227
    zf-C2H2_jaz; Zinc-finger double-stranded RNA-binding

  3. XM_021468063.1 → XP_021323738.1  tRNA dimethylallyltransferase, mitochondrial isoform X3

    UniProtKB/TrEMBL
    A0A8M9PAY7
    Conserved Domains (2) summary
    pfam01715
    Location:1 → 161
    IPPT; IPP transferase
    pfam12171
    Location:223 → 247
    zf-C2H2_jaz; Zinc-finger double-stranded RNA-binding

  4. XM_021468061.1 → XP_021323736.1  tRNA dimethylallyltransferase, mitochondrial isoform X2

    UniProtKB/TrEMBL
    A0A8M9PNA5
    Conserved Domains (1) summary
    cl21455
    Location:13 → 249
    P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases

  5. XM_021468062.1 → XP_021323737.1  tRNA dimethylallyltransferase, mitochondrial isoform X2

    UniProtKB/TrEMBL
    A0A8M9PNA5
    Related
    ENSDARP00000110903.1, ENSDART00000125893.2
    Conserved Domains (1) summary
    cl21455
    Location:13 → 249
    P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases

RNA

  1. XR_002456105.1 RNA Sequence

Reference GRCz11 ALT_DRER_TU_1

Genomic

  1. NW_018395051.1 Reference GRCz11 ALT_DRER_TU_1

    Range
    24935..95364 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version

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