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PBRM1 polybromo 1 [ Homo sapiens (human) ]

Gene ID: 55193, updated on 3-Apr-2024

Summary

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Official Symbol
PBRM1provided by HGNC
Official Full Name
polybromo 1provided by HGNC
Primary source
HGNC:HGNC:30064
See related
Ensembl:ENSG00000163939 MIM:606083; AllianceGenome:HGNC:30064
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
PB1; RCC; BAF180; SMARCH1
Summary
This locus encodes a subunit of ATP-dependent chromatin-remodeling complexes. The encoded protein has been identified as in integral component of complexes necessary for ligand-dependent transcriptional activation by nuclear hormone receptors. Mutations at this locus have been associated with primary clear cell renal cell carcinoma. [provided by RefSeq, Feb 2012]
Expression
Ubiquitous expression in thyroid (RPKM 10.3), ovary (RPKM 8.8) and 25 other tissues See more
Orthologs
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Genomic context

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Location:
3p21.1
Exon count:
39
Annotation release Status Assembly Chr Location
RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 3 NC_000003.12 (52545367..52685913, complement)
RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 3 NC_060927.1 (52578272..52718824, complement)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 3 NC_000003.11 (52579383..52719929, complement)

Chromosome 3 - NC_000003.12Genomic Context describing neighboring genes Neighboring gene stabilin 1 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 19943 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 14445 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 14446 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 14447 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 14448 Neighboring gene H3K27ac hESC enhancer GRCh37_chr3:52570940-52571473 Neighboring gene 5'-nucleotidase domain containing 2 Neighboring gene ubiquinol-cytochrome c reductase complex assembly factor 5 Neighboring gene RNA, U6 small nuclear 856, pseudogene Neighboring gene RNA, U6atac small nuclear 16, pseudogene Neighboring gene MPRA-validated peak4655 silencer Neighboring gene H3K27ac hESC enhancer GRCh37_chr3:52699923-52700424 Neighboring gene H3K27ac hESC enhancer GRCh37_chr3:52700425-52700924 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 19944 Neighboring gene H3K27ac hESC enhancer GRCh37_chr3:52719523-52720211 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 19945 Neighboring gene small nucleolar RNA, C/D box 136 Neighboring gene small nucleolar RNA, C/D box 19 Neighboring gene G protein nucleolar 3

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

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Related articles in PubMed

  1. Relationship between body composition and PBRM1 mutations in clear cell renal cell carcinoma: a propensity score matching analysis. Demirel E, et al. Rev Assoc Med Bras (1992), 2023. PMID 37222312, Free PMC Article
  2. PBRM1 bromodomains associate with RNA to facilitate chromatin association. De Silva SM, et al. Nucleic Acids Res, 2023 May 8. PMID 36808431, Free PMC Article
  3. Non‑small cell lung cancer carrying PBRM1 mutation suggests an immunologically cold phenotype leading to immunotherapy failure even with high TMB. Miao XY, et al. Sci Rep, 2022 Dec 1. PMID 36456601, Free PMC Article
  4. PBRM1 presents a potential prognostic marker and therapeutic target in duodenal papillary carcinoma. He X, et al. Clin Transl Med, 2022 Oct. PMID 36178086, Free PMC Article
  5. Clinicopathological Significance, Related Molecular Changes and Tumor Immune Response Analysis of the Abnormal SWI/SNF Complex Subunit PBRM1 in Gastric Adenocarcinoma. Zhou Z, et al. Pathol Oncol Res, 2022. PMID 35928964, Free PMC Article

See all (206) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Multi-omics integration identifies cell-state-specific repression by PBRM1-PIAS1 cooperation.
    Title: Multi-omics integration identifies cell-state-specific repression by PBRM1-PIAS1 cooperation.
  2. Relationship between body composition and PBRM1 mutations in clear cell renal cell carcinoma: a propensity score matching analysis.
    Title: Relationship between body composition and PBRM1 mutations in clear cell renal cell carcinoma: a propensity score matching analysis.
  3. PBRM1-deficient PBAF complexes target aberrant genomic loci to activate the NF-kappaB pathway in clear cell renal cell carcinoma.
    Title: PBRM1-deficient PBAF complexes target aberrant genomic loci to activate the NF-κB pathway in clear cell renal cell carcinoma.
  4. PBRM1 bromodomains associate with RNA to facilitate chromatin association.
    Title: PBRM1 bromodomains associate with RNA to facilitate chromatin association.
  5. MUC1-C Dictates PBRM1-Mediated Chronic Induction of Interferon Signaling, DNA Damage Resistance, and Immunosuppression in Triple-Negative Breast Cancer.
    Title: MUC1-C Dictates PBRM1-Mediated Chronic Induction of Interferon Signaling, DNA Damage Resistance, and Immunosuppression in Triple-Negative Breast Cancer.
  6. PBRM1, SETD2 and BAP1 - the trinity of 3p in clear cell renal cell carcinoma.
    Title: PBRM1, SETD2 and BAP1 - the trinity of 3p in clear cell renal cell carcinoma.
  7. Nonsmall cell lung cancer carrying PBRM1 mutation suggests an immunologically cold phenotype leading to immunotherapy failure even with high TMB.
    Title: Non‑small cell lung cancer carrying PBRM1 mutation suggests an immunologically cold phenotype leading to immunotherapy failure even with high TMB.
  8. Interrogating the Significance of PARP1 Expression and PBRM1 Mutation as Biomarkers for Predicting the Response to Atezolizumab plus Bevacizumab or to Sunitinib in Patients with Clear Cell Renal Cell Carcinoma.
    Title: Interrogating the Significance of PARP1 Expression and PBRM1 Mutation as Biomarkers for Predicting the Response to Atezolizumab plus Bevacizumab or to Sunitinib in Patients with Clear Cell Renal Cell Carcinoma.
  9. PBRM1 presents a potential prognostic marker and therapeutic target in duodenal papillary carcinoma.
    Title: PBRM1 presents a potential prognostic marker and therapeutic target in duodenal papillary carcinoma.
  10. Clinicopathological Significance, Related Molecular Changes and Tumor Immune Response Analysis of the Abnormal SWI/SNF Complex Subunit PBRM1 in Gastric Adenocarcinoma.
    Title: Clinicopathological Significance, Related Molecular Changes and Tumor Immune Response Analysis of the Abnormal SWI/SNF Complex Subunit PBRM1 in Gastric Adenocarcinoma.
Submit: New GeneRIF Correction See all GeneRIFs (80)

Phenotypes

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Find tests for this gene in the NIH Genetic Testing Registry (GTR)

Review eQTL and phenotype association data in this region using PheGenI

Associated conditions

Description Tests
Nonpapillary renal cell carcinoma
MedGen: CN074294 OMIM: 144700 GeneReviews: Not available
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EBI GWAS Catalog

Description
Biological insights from 108 schizophrenia-associated genetic loci.
EBI GWAS Catalog
Genome-wide association analysis identifies 13 new risk loci for schizophrenia.
EBI GWAS Catalog
Genome-wide association of mood-incongruent psychotic bipolar disorder.
EBI GWAS Catalog
Identification of new susceptibility loci for osteoarthritis (arcOGEN): a genome-wide association study.
EBI GWAS Catalog
Large-scale genome-wide association analysis of bipolar disorder identifies a new susceptibility locus near ODZ4.
EBI GWAS Catalog
Meta-analysis of genome-wide association data identifies a risk locus for major mood disorders on 3p21.1.
EBI GWAS Catalog
Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals.
EBI GWAS Catalog

Variation

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See variants in ClinVar

See studies and variants in dbVar

See Variation Viewer (GRCh37.p13)

See Variation Viewer (GRCh38)

Genotypes

HIV-1 interactions

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Protein interactions

Protein Gene Interaction Pubs
Tat tat BAF180 is involved in HIV-1 Tat-dependent HIV promoter activity. BAF180 has no effect on LTR activation by HIV-1 Tat K50,51R mutant PubMed
tat Most of the components of the SWI2/SNF2 chromatin remodeling complex (BRG1/BRM, BAF250, BAF180, BAF170, BAF155, BAF60a, BAF53A, actin and InI) except BRM, BAF155 and BAF57, are identified to interact with HIV-1 Tat in Jurkat cell PubMed

Go to the HIV-1, Human Interaction Database

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Clone Names

  • MGC156155, MGC156156

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
  
enables chromatin binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables chromatin binding NAS
Non-traceable Author Statement
more info
 PubMed 
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
Process Evidence Code Pubs
involved_in chromatin remodeling IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in chromatin remodeling NAS
Non-traceable Author Statement
more info
 PubMed 
involved_in chromatin remodeling TAS
Traceable Author Statement
more info
 PubMed 
involved_in mitotic cell cycle TAS
Traceable Author Statement
more info
 PubMed 
involved_in negative regulation of cell population proliferation IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in positive regulation of T cell differentiation NAS
Non-traceable Author Statement
more info
 PubMed 
involved_in positive regulation of cell differentiation NAS
Non-traceable Author Statement
more info
 PubMed 
involved_in positive regulation of double-strand break repair NAS
Non-traceable Author Statement
more info
 PubMed 
involved_in positive regulation of myoblast differentiation NAS
Non-traceable Author Statement
more info
 PubMed 
involved_in regulation of G0 to G1 transition NAS
Non-traceable Author Statement
more info
 PubMed 
involved_in regulation of G1/S transition of mitotic cell cycle NAS
Non-traceable Author Statement
more info
 PubMed 
involved_in regulation of mitotic metaphase/anaphase transition NAS
Non-traceable Author Statement
more info
 PubMed 
involved_in regulation of nucleotide-excision repair NAS
Non-traceable Author Statement
more info
 PubMed 
involved_in regulation of transcription by RNA polymerase II NAS
Non-traceable Author Statement
more info
 PubMed 
involved_in transcription elongation by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
part_of RSC-type complex IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of RSC-type complex NAS
Non-traceable Author Statement
more info
 PubMed 
part_of SWI/SNF complex IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of SWI/SNF complex IDA
Inferred from Direct Assay
more info
 PubMed 
part_of chromatin NAS
Non-traceable Author Statement
more info
 PubMed 
located_in kinetochore NAS
Non-traceable Author Statement
more info
 PubMed 
located_in nuclear chromosome NAS
Non-traceable Author Statement
more info
 PubMed 
located_in nuclear matrix NAS
Non-traceable Author Statement
more info
 PubMed 
located_in nucleoplasm IDA
Inferred from Direct Assay
more info
  
located_in nucleus IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
protein polybromo-1
Names
BRG1-associated factor 180
polybromo-1D

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_032108.1 RefSeqGene

    Range
    4938..145484
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001350074.2 → NP_001337003.1  protein polybromo-1 isoform 5

    Status: REVIEWED

    Description
    Transcript Variant: This variant (5) encodes the longest isoform (5). Variants 5 and 9 encode the same isoform (5).
    Source sequence(s)
    AC104446, AF177387, AK001507, BC129935, CA438315, CD691117
    UniProtKB/TrEMBL
    E7EVG2
    Conserved Domains (8) summary
    cd05515
    Location:694 → 798
    Bromo_polybromo_V; Bromodomain, polybromo repeat V. Polybromo is a nuclear protein of unknown function, which contains 6 bromodomains. The human ortholog BAF180 is part of a SWI/SNF chromatin-remodeling complex, and it may carry out the functions of Yeast Rsc-1 and Rsc-2. ...
    cd05517
    Location:203 → 305
    Bromo_polybromo_II; Bromodomain, polybromo repeat II. Polybromo is a nuclear protein of unknown function, which contains 6 bromodomains. The human ortholog BAF180 is part of a SWI/SNF chromatin-remodeling complex, and it may carry out the functions of Yeast Rsc-1 and Rsc-2. ...
    cd05518
    Location:555 → 658
    Bromo_polybromo_IV; Bromodomain, polybromo repeat IV. Polybromo is a nuclear protein of unknown function, which contains 6 bromodomains. The human ortholog BAF180 is part of a SWI/SNF chromatin-remodeling complex, and it may carry out the functions of Yeast Rsc-1 and Rsc-2. ...
    cd05520
    Location:404 → 505
    Bromo_polybromo_III; Bromodomain, polybromo repeat III. Polybromo is a nuclear protein of unknown function, which contains 6 bromodomains. The human ortholog BAF180 is part of a SWI/SNF chromatin-remodeling complex, and it may carry out the functions of Yeast Rsc-1 and Rsc-2. ...
    cd05524
    Location:65 → 177
    Bromo_polybromo_I; Bromodomain, polybromo repeat I. Polybromo is a nuclear protein of unknown function, which contains 6 bromodomains. The human ortholog BAF180 is part of a SWI/SNF chromatin-remodeling complex, and it may carry out the functions of Yeast Rsc-1 and Rsc-2. ...
    cd05526
    Location:811 → 918
    Bromo_polybromo_VI; Bromodomain, polybromo repeat VI. Polybromo is a nuclear protein of unknown function, which contains 6 bromodomains. The human ortholog BAF180 is part of a SWI/SNF chromatin-remodeling complex, and it may carry out the functions of Yeast Rsc-1 and Rsc-2. ...
    cd00084
    Location:1416 → 1465
    HMG-box; High Mobility Group (HMG)-box is found in a variety of eukaryotic chromosomal proteins and transcription factors. HMGs bind to the minor groove of DNA and have been classified by DNA binding preferences. Two phylogenically distinct groups of Class I ...
    cd04717
    Location:993 → 1110
    BAH_polybromo; BAH, or Bromo Adjacent Homology domain, as present in polybromo and yeast RSC1/2. The human polybromo protein (BAF180) is a component of the SWI/SNF chromatin-remodeling complex PBAF. It is thought that polybromo participates in transcriptional ...

  2. NM_001350075.2 → NP_001337004.1  protein polybromo-1 isoform 6

    Status: REVIEWED

    Description
    Transcript Variant: This variant (6) differs in the 5' UTR, uses a downstream start codon and contains multiple coding region differences, compared to variant 5. It encodes isoform 6, which is shorter than isoform 5.
    Source sequence(s)
    AC104446, AF177387, AK001507, BC115011, BF592839, CA438315
    Consensus CDS
    CCDS87087.1
    UniProtKB/TrEMBL
    E7EVG2
    Conserved Domains (8) summary
    cd05515
    Location:658 → 762
    Bromo_polybromo_V; Bromodomain, polybromo repeat V. Polybromo is a nuclear protein of unknown function, which contains 6 bromodomains. The human ortholog BAF180 is part of a SWI/SNF chromatin-remodeling complex, and it may carry out the functions of Yeast Rsc-1 and Rsc-2. ...
    cd05517
    Location:182 → 284
    Bromo_polybromo_II; Bromodomain, polybromo repeat II. Polybromo is a nuclear protein of unknown function, which contains 6 bromodomains. The human ortholog BAF180 is part of a SWI/SNF chromatin-remodeling complex, and it may carry out the functions of Yeast Rsc-1 and Rsc-2. ...
    cd05518
    Location:519 → 622
    Bromo_polybromo_IV; Bromodomain, polybromo repeat IV. Polybromo is a nuclear protein of unknown function, which contains 6 bromodomains. The human ortholog BAF180 is part of a SWI/SNF chromatin-remodeling complex, and it may carry out the functions of Yeast Rsc-1 and Rsc-2. ...
    cd05520
    Location:383 → 484
    Bromo_polybromo_III; Bromodomain, polybromo repeat III. Polybromo is a nuclear protein of unknown function, which contains 6 bromodomains. The human ortholog BAF180 is part of a SWI/SNF chromatin-remodeling complex, and it may carry out the functions of Yeast Rsc-1 and Rsc-2. ...
    cd05524
    Location:44 → 156
    Bromo_polybromo_I; Bromodomain, polybromo repeat I. Polybromo is a nuclear protein of unknown function, which contains 6 bromodomains. The human ortholog BAF180 is part of a SWI/SNF chromatin-remodeling complex, and it may carry out the functions of Yeast Rsc-1 and Rsc-2. ...
    cd05526
    Location:775 → 882
    Bromo_polybromo_VI; Bromodomain, polybromo repeat VI. Polybromo is a nuclear protein of unknown function, which contains 6 bromodomains. The human ortholog BAF180 is part of a SWI/SNF chromatin-remodeling complex, and it may carry out the functions of Yeast Rsc-1 and Rsc-2. ...
    cd00084
    Location:1380 → 1429
    HMG-box; High Mobility Group (HMG)-box is found in a variety of eukaryotic chromosomal proteins and transcription factors. HMGs bind to the minor groove of DNA and have been classified by DNA binding preferences. Two phylogenically distinct groups of Class I ...
    cd04717
    Location:957 → 1074
    BAH_polybromo; BAH, or Bromo Adjacent Homology domain, as present in polybromo and yeast RSC1/2. The human polybromo protein (BAF180) is a component of the SWI/SNF chromatin-remodeling complex PBAF. It is thought that polybromo participates in transcriptional ...

  3. NM_001350076.2 → NP_001337005.1  protein polybromo-1 isoform 7

    Status: REVIEWED

    Description
    Transcript Variant: This variant (7) differs in the 5' UTR and contains an alternate in-frame splice site in the 3' coding region, compared to variant 5. It encodes isoform 7, which is shorter than isoform 5.
    Source sequence(s)
    AC104446, AF177387, AI392948, AK001507, BC129934, CA438315, DA801725
    UniProtKB/TrEMBL
    E7EVG2
    Conserved Domains (8) summary
    cd05515
    Location:694 → 798
    Bromo_polybromo_V; Bromodomain, polybromo repeat V. Polybromo is a nuclear protein of unknown function, which contains 6 bromodomains. The human ortholog BAF180 is part of a SWI/SNF chromatin-remodeling complex, and it may carry out the functions of Yeast Rsc-1 and Rsc-2. ...
    cd05517
    Location:203 → 305
    Bromo_polybromo_II; Bromodomain, polybromo repeat II. Polybromo is a nuclear protein of unknown function, which contains 6 bromodomains. The human ortholog BAF180 is part of a SWI/SNF chromatin-remodeling complex, and it may carry out the functions of Yeast Rsc-1 and Rsc-2. ...
    cd05518
    Location:555 → 658
    Bromo_polybromo_IV; Bromodomain, polybromo repeat IV. Polybromo is a nuclear protein of unknown function, which contains 6 bromodomains. The human ortholog BAF180 is part of a SWI/SNF chromatin-remodeling complex, and it may carry out the functions of Yeast Rsc-1 and Rsc-2. ...
    cd05520
    Location:404 → 505
    Bromo_polybromo_III; Bromodomain, polybromo repeat III. Polybromo is a nuclear protein of unknown function, which contains 6 bromodomains. The human ortholog BAF180 is part of a SWI/SNF chromatin-remodeling complex, and it may carry out the functions of Yeast Rsc-1 and Rsc-2. ...
    cd05524
    Location:65 → 177
    Bromo_polybromo_I; Bromodomain, polybromo repeat I. Polybromo is a nuclear protein of unknown function, which contains 6 bromodomains. The human ortholog BAF180 is part of a SWI/SNF chromatin-remodeling complex, and it may carry out the functions of Yeast Rsc-1 and Rsc-2. ...
    cd05526
    Location:811 → 918
    Bromo_polybromo_VI; Bromodomain, polybromo repeat VI. Polybromo is a nuclear protein of unknown function, which contains 6 bromodomains. The human ortholog BAF180 is part of a SWI/SNF chromatin-remodeling complex, and it may carry out the functions of Yeast Rsc-1 and Rsc-2. ...
    cd00084
    Location:1415 → 1464
    HMG-box; High Mobility Group (HMG)-box is found in a variety of eukaryotic chromosomal proteins and transcription factors. HMGs bind to the minor groove of DNA and have been classified by DNA binding preferences. Two phylogenically distinct groups of Class I ...
    cd04717
    Location:992 → 1109
    BAH_polybromo; BAH, or Bromo Adjacent Homology domain, as present in polybromo and yeast RSC1/2. The human polybromo protein (BAF180) is a component of the SWI/SNF chromatin-remodeling complex PBAF. It is thought that polybromo participates in transcriptional ...

  4. NM_001350077.2 → NP_001337006.1  protein polybromo-1 isoform 8

    Status: REVIEWED

    Description
    Transcript Variant: This variant (8) differs in the 5' UTR and uses an alternate in-frame splice site in the 5' coding region, compared to variant 5. It encodes isoform 8, which is shorter than isoform 5.
    Source sequence(s)
    AA724453, AC104446, AF177387, AK001507, BC129935, CA438315, CD691117, DA801725
    UniProtKB/TrEMBL
    E7EVG2
    Conserved Domains (8) summary
    cd05515
    Location:691 → 795
    Bromo_polybromo_V; Bromodomain, polybromo repeat V. Polybromo is a nuclear protein of unknown function, which contains 6 bromodomains. The human ortholog BAF180 is part of a SWI/SNF chromatin-remodeling complex, and it may carry out the functions of Yeast Rsc-1 and Rsc-2. ...
    cd05517
    Location:200 → 302
    Bromo_polybromo_II; Bromodomain, polybromo repeat II. Polybromo is a nuclear protein of unknown function, which contains 6 bromodomains. The human ortholog BAF180 is part of a SWI/SNF chromatin-remodeling complex, and it may carry out the functions of Yeast Rsc-1 and Rsc-2. ...
    cd05518
    Location:552 → 655
    Bromo_polybromo_IV; Bromodomain, polybromo repeat IV. Polybromo is a nuclear protein of unknown function, which contains 6 bromodomains. The human ortholog BAF180 is part of a SWI/SNF chromatin-remodeling complex, and it may carry out the functions of Yeast Rsc-1 and Rsc-2. ...
    cd05520
    Location:401 → 502
    Bromo_polybromo_III; Bromodomain, polybromo repeat III. Polybromo is a nuclear protein of unknown function, which contains 6 bromodomains. The human ortholog BAF180 is part of a SWI/SNF chromatin-remodeling complex, and it may carry out the functions of Yeast Rsc-1 and Rsc-2. ...
    cd05524
    Location:62 → 174
    Bromo_polybromo_I; Bromodomain, polybromo repeat I. Polybromo is a nuclear protein of unknown function, which contains 6 bromodomains. The human ortholog BAF180 is part of a SWI/SNF chromatin-remodeling complex, and it may carry out the functions of Yeast Rsc-1 and Rsc-2. ...
    cd05526
    Location:808 → 915
    Bromo_polybromo_VI; Bromodomain, polybromo repeat VI. Polybromo is a nuclear protein of unknown function, which contains 6 bromodomains. The human ortholog BAF180 is part of a SWI/SNF chromatin-remodeling complex, and it may carry out the functions of Yeast Rsc-1 and Rsc-2. ...
    cd00084
    Location:1413 → 1462
    HMG-box; High Mobility Group (HMG)-box is found in a variety of eukaryotic chromosomal proteins and transcription factors. HMGs bind to the minor groove of DNA and have been classified by DNA binding preferences. Two phylogenically distinct groups of Class I ...
    cd04717
    Location:990 → 1107
    BAH_polybromo; BAH, or Bromo Adjacent Homology domain, as present in polybromo and yeast RSC1/2. The human polybromo protein (BAF180) is a component of the SWI/SNF chromatin-remodeling complex PBAF. It is thought that polybromo participates in transcriptional ...

  5. NM_001350078.2 → NP_001337007.1  protein polybromo-1 isoform 5

    Status: REVIEWED

    Description
    Transcript Variant: This variant (9) differs in the 5' UTR compared to variant 5. Variants 5 and 9 encode the same isoform (5).
    Source sequence(s)
    AC104446, AF225872, AI392948, AK001507, BC129935, CA438315, DA801725
    UniProtKB/TrEMBL
    E7EVG2
    Conserved Domains (8) summary
    cd05515
    Location:694 → 798
    Bromo_polybromo_V; Bromodomain, polybromo repeat V. Polybromo is a nuclear protein of unknown function, which contains 6 bromodomains. The human ortholog BAF180 is part of a SWI/SNF chromatin-remodeling complex, and it may carry out the functions of Yeast Rsc-1 and Rsc-2. ...
    cd05517
    Location:203 → 305
    Bromo_polybromo_II; Bromodomain, polybromo repeat II. Polybromo is a nuclear protein of unknown function, which contains 6 bromodomains. The human ortholog BAF180 is part of a SWI/SNF chromatin-remodeling complex, and it may carry out the functions of Yeast Rsc-1 and Rsc-2. ...
    cd05518
    Location:555 → 658
    Bromo_polybromo_IV; Bromodomain, polybromo repeat IV. Polybromo is a nuclear protein of unknown function, which contains 6 bromodomains. The human ortholog BAF180 is part of a SWI/SNF chromatin-remodeling complex, and it may carry out the functions of Yeast Rsc-1 and Rsc-2. ...
    cd05520
    Location:404 → 505
    Bromo_polybromo_III; Bromodomain, polybromo repeat III. Polybromo is a nuclear protein of unknown function, which contains 6 bromodomains. The human ortholog BAF180 is part of a SWI/SNF chromatin-remodeling complex, and it may carry out the functions of Yeast Rsc-1 and Rsc-2. ...
    cd05524
    Location:65 → 177
    Bromo_polybromo_I; Bromodomain, polybromo repeat I. Polybromo is a nuclear protein of unknown function, which contains 6 bromodomains. The human ortholog BAF180 is part of a SWI/SNF chromatin-remodeling complex, and it may carry out the functions of Yeast Rsc-1 and Rsc-2. ...
    cd05526
    Location:811 → 918
    Bromo_polybromo_VI; Bromodomain, polybromo repeat VI. Polybromo is a nuclear protein of unknown function, which contains 6 bromodomains. The human ortholog BAF180 is part of a SWI/SNF chromatin-remodeling complex, and it may carry out the functions of Yeast Rsc-1 and Rsc-2. ...
    cd00084
    Location:1416 → 1465
    HMG-box; High Mobility Group (HMG)-box is found in a variety of eukaryotic chromosomal proteins and transcription factors. HMGs bind to the minor groove of DNA and have been classified by DNA binding preferences. Two phylogenically distinct groups of Class I ...
    cd04717
    Location:993 → 1110
    BAH_polybromo; BAH, or Bromo Adjacent Homology domain, as present in polybromo and yeast RSC1/2. The human polybromo protein (BAF180) is a component of the SWI/SNF chromatin-remodeling complex PBAF. It is thought that polybromo participates in transcriptional ...

  6. NM_001350079.2 → NP_001337008.1  protein polybromo-1 isoform 9

    Status: REVIEWED

    Description
    Transcript Variant: This variant (10) differs in the 5' UTR and contains multiple differences in the coding region, compared to variant 5. It encodes isoform 9, which is shorter than isoform 5.
    Source sequence(s)
    AC104446, AF225872, AK001507, BF592839, CA438315, DA801725
    UniProtKB/TrEMBL
    E7EVG2
    Conserved Domains (9) summary
    cd05515
    Location:679 → 783
    Bromo_polybromo_V; Bromodomain, polybromo repeat V. Polybromo is a nuclear protein of unknown function, which contains 6 bromodomains. The human ortholog BAF180 is part of a SWI/SNF chromatin-remodeling complex, and it may carry out the functions of Yeast Rsc-1 and Rsc-2. ...
    cd05517
    Location:203 → 305
    Bromo_polybromo_II; Bromodomain, polybromo repeat II. Polybromo is a nuclear protein of unknown function, which contains 6 bromodomains. The human ortholog BAF180 is part of a SWI/SNF chromatin-remodeling complex, and it may carry out the functions of Yeast Rsc-1 and Rsc-2. ...
    cd05518
    Location:540 → 643
    Bromo_polybromo_IV; Bromodomain, polybromo repeat IV. Polybromo is a nuclear protein of unknown function, which contains 6 bromodomains. The human ortholog BAF180 is part of a SWI/SNF chromatin-remodeling complex, and it may carry out the functions of Yeast Rsc-1 and Rsc-2. ...
    cd05520
    Location:404 → 505
    Bromo_polybromo_III; Bromodomain, polybromo repeat III. Polybromo is a nuclear protein of unknown function, which contains 6 bromodomains. The human ortholog BAF180 is part of a SWI/SNF chromatin-remodeling complex, and it may carry out the functions of Yeast Rsc-1 and Rsc-2. ...
    cd05524
    Location:65 → 177
    Bromo_polybromo_I; Bromodomain, polybromo repeat I. Polybromo is a nuclear protein of unknown function, which contains 6 bromodomains. The human ortholog BAF180 is part of a SWI/SNF chromatin-remodeling complex, and it may carry out the functions of Yeast Rsc-1 and Rsc-2. ...
    cd05526
    Location:796 → 903
    Bromo_polybromo_VI; Bromodomain, polybromo repeat VI. Polybromo is a nuclear protein of unknown function, which contains 6 bromodomains. The human ortholog BAF180 is part of a SWI/SNF chromatin-remodeling complex, and it may carry out the functions of Yeast Rsc-1 and Rsc-2. ...
    cd00084
    Location:1376 → 1425
    HMG-box; High Mobility Group (HMG)-box is found in a variety of eukaryotic chromosomal proteins and transcription factors. HMGs bind to the minor groove of DNA and have been classified by DNA binding preferences. Two phylogenically distinct groups of Class I ...
    cd04717
    Location:1151 → 1269
    BAH_polybromo; BAH, or Bromo Adjacent Homology domain, as present in polybromo and yeast RSC1/2. The human polybromo protein (BAF180) is a component of the SWI/SNF chromatin-remodeling complex PBAF. It is thought that polybromo participates in transcriptional ...
    cl02608
    Location:978 → 1070
    BAH; BAH, or Bromo Adjacent Homology domain (also called ELM1 and BAM for Bromo Adjacent Motif). BAH domains have first been described as domains found in the polybromo protein and Yeast Rsc1/Rsc2 (Remodeling of the Structure of Chromatin). They also occur in ...

  7. NM_001366070.2 → NP_001352999.1  protein polybromo-1 isoform 5

    Status: REVIEWED

    Source sequence(s)
    AC104446, AC112215
    UniProtKB/TrEMBL
    E7EVG2
    Conserved Domains (8) summary
    cd05515
    Location:694 → 798
    Bromo_polybromo_V; Bromodomain, polybromo repeat V. Polybromo is a nuclear protein of unknown function, which contains 6 bromodomains. The human ortholog BAF180 is part of a SWI/SNF chromatin-remodeling complex, and it may carry out the functions of Yeast Rsc-1 and Rsc-2. ...
    cd05517
    Location:203 → 305
    Bromo_polybromo_II; Bromodomain, polybromo repeat II. Polybromo is a nuclear protein of unknown function, which contains 6 bromodomains. The human ortholog BAF180 is part of a SWI/SNF chromatin-remodeling complex, and it may carry out the functions of Yeast Rsc-1 and Rsc-2. ...
    cd05518
    Location:555 → 658
    Bromo_polybromo_IV; Bromodomain, polybromo repeat IV. Polybromo is a nuclear protein of unknown function, which contains 6 bromodomains. The human ortholog BAF180 is part of a SWI/SNF chromatin-remodeling complex, and it may carry out the functions of Yeast Rsc-1 and Rsc-2. ...
    cd05520
    Location:404 → 505
    Bromo_polybromo_III; Bromodomain, polybromo repeat III. Polybromo is a nuclear protein of unknown function, which contains 6 bromodomains. The human ortholog BAF180 is part of a SWI/SNF chromatin-remodeling complex, and it may carry out the functions of Yeast Rsc-1 and Rsc-2. ...
    cd05524
    Location:65 → 177
    Bromo_polybromo_I; Bromodomain, polybromo repeat I. Polybromo is a nuclear protein of unknown function, which contains 6 bromodomains. The human ortholog BAF180 is part of a SWI/SNF chromatin-remodeling complex, and it may carry out the functions of Yeast Rsc-1 and Rsc-2. ...
    cd05526
    Location:811 → 918
    Bromo_polybromo_VI; Bromodomain, polybromo repeat VI. Polybromo is a nuclear protein of unknown function, which contains 6 bromodomains. The human ortholog BAF180 is part of a SWI/SNF chromatin-remodeling complex, and it may carry out the functions of Yeast Rsc-1 and Rsc-2. ...
    cd00084
    Location:1416 → 1465
    HMG-box; High Mobility Group (HMG)-box is found in a variety of eukaryotic chromosomal proteins and transcription factors. HMGs bind to the minor groove of DNA and have been classified by DNA binding preferences. Two phylogenically distinct groups of Class I ...
    cd04717
    Location:993 → 1110
    BAH_polybromo; BAH, or Bromo Adjacent Homology domain, as present in polybromo and yeast RSC1/2. The human polybromo protein (BAF180) is a component of the SWI/SNF chromatin-remodeling complex PBAF. It is thought that polybromo participates in transcriptional ...

  8. NM_001366071.2 → NP_001353000.1  protein polybromo-1 isoform 10

    Status: REVIEWED

    Source sequence(s)
    AC104446, AC112215
    UniProtKB/TrEMBL
    E7EVG2
    Conserved Domains (9) summary
    cd05515
    Location:679 → 783
    Bromo_polybromo_V; Bromodomain, polybromo repeat V. Polybromo is a nuclear protein of unknown function, which contains 6 bromodomains. The human ortholog BAF180 is part of a SWI/SNF chromatin-remodeling complex, and it may carry out the functions of Yeast Rsc-1 and Rsc-2. ...
    cd05517
    Location:203 → 305
    Bromo_polybromo_II; Bromodomain, polybromo repeat II. Polybromo is a nuclear protein of unknown function, which contains 6 bromodomains. The human ortholog BAF180 is part of a SWI/SNF chromatin-remodeling complex, and it may carry out the functions of Yeast Rsc-1 and Rsc-2. ...
    cd05518
    Location:540 → 643
    Bromo_polybromo_IV; Bromodomain, polybromo repeat IV. Polybromo is a nuclear protein of unknown function, which contains 6 bromodomains. The human ortholog BAF180 is part of a SWI/SNF chromatin-remodeling complex, and it may carry out the functions of Yeast Rsc-1 and Rsc-2. ...
    cd05520
    Location:404 → 505
    Bromo_polybromo_III; Bromodomain, polybromo repeat III. Polybromo is a nuclear protein of unknown function, which contains 6 bromodomains. The human ortholog BAF180 is part of a SWI/SNF chromatin-remodeling complex, and it may carry out the functions of Yeast Rsc-1 and Rsc-2. ...
    cd05524
    Location:65 → 177
    Bromo_polybromo_I; Bromodomain, polybromo repeat I. Polybromo is a nuclear protein of unknown function, which contains 6 bromodomains. The human ortholog BAF180 is part of a SWI/SNF chromatin-remodeling complex, and it may carry out the functions of Yeast Rsc-1 and Rsc-2. ...
    cd05526
    Location:796 → 903
    Bromo_polybromo_VI; Bromodomain, polybromo repeat VI. Polybromo is a nuclear protein of unknown function, which contains 6 bromodomains. The human ortholog BAF180 is part of a SWI/SNF chromatin-remodeling complex, and it may carry out the functions of Yeast Rsc-1 and Rsc-2. ...
    cd00084
    Location:1401 → 1465
    HMG-box; High Mobility Group (HMG)-box is found in a variety of eukaryotic chromosomal proteins and transcription factors. HMGs bind to the minor groove of DNA and have been classified by DNA binding preferences. Two phylogenically distinct groups of Class I ...
    cd04717
    Location:978 → 1095
    BAH_polybromo; BAH, or Bromo Adjacent Homology domain, as present in polybromo and yeast RSC1/2. The human polybromo protein (BAF180) is a component of the SWI/SNF chromatin-remodeling complex PBAF. It is thought that polybromo participates in transcriptional ...
    pfam11593
    Location:1445 → 1529
    Med3; Mediator complex subunit 3 fungal

  9. NM_001366072.2 → NP_001353001.1  protein polybromo-1 isoform 11

    Status: REVIEWED

    Source sequence(s)
    AC104446, AC112215
    UniProtKB/TrEMBL
    E7EVG2
    Conserved Domains (8) summary
    cd05515
    Location:679 → 783
    Bromo_polybromo_V; Bromodomain, polybromo repeat V. Polybromo is a nuclear protein of unknown function, which contains 6 bromodomains. The human ortholog BAF180 is part of a SWI/SNF chromatin-remodeling complex, and it may carry out the functions of Yeast Rsc-1 and Rsc-2. ...
    cd05517
    Location:203 → 305
    Bromo_polybromo_II; Bromodomain, polybromo repeat II. Polybromo is a nuclear protein of unknown function, which contains 6 bromodomains. The human ortholog BAF180 is part of a SWI/SNF chromatin-remodeling complex, and it may carry out the functions of Yeast Rsc-1 and Rsc-2. ...
    cd05518
    Location:540 → 643
    Bromo_polybromo_IV; Bromodomain, polybromo repeat IV. Polybromo is a nuclear protein of unknown function, which contains 6 bromodomains. The human ortholog BAF180 is part of a SWI/SNF chromatin-remodeling complex, and it may carry out the functions of Yeast Rsc-1 and Rsc-2. ...
    cd05520
    Location:404 → 505
    Bromo_polybromo_III; Bromodomain, polybromo repeat III. Polybromo is a nuclear protein of unknown function, which contains 6 bromodomains. The human ortholog BAF180 is part of a SWI/SNF chromatin-remodeling complex, and it may carry out the functions of Yeast Rsc-1 and Rsc-2. ...
    cd05524
    Location:65 → 177
    Bromo_polybromo_I; Bromodomain, polybromo repeat I. Polybromo is a nuclear protein of unknown function, which contains 6 bromodomains. The human ortholog BAF180 is part of a SWI/SNF chromatin-remodeling complex, and it may carry out the functions of Yeast Rsc-1 and Rsc-2. ...
    cd05526
    Location:796 → 903
    Bromo_polybromo_VI; Bromodomain, polybromo repeat VI. Polybromo is a nuclear protein of unknown function, which contains 6 bromodomains. The human ortholog BAF180 is part of a SWI/SNF chromatin-remodeling complex, and it may carry out the functions of Yeast Rsc-1 and Rsc-2. ...
    cd00084
    Location:1401 → 1450
    HMG-box; High Mobility Group (HMG)-box is found in a variety of eukaryotic chromosomal proteins and transcription factors. HMGs bind to the minor groove of DNA and have been classified by DNA binding preferences. Two phylogenically distinct groups of Class I ...
    cd04717
    Location:978 → 1095
    BAH_polybromo; BAH, or Bromo Adjacent Homology domain, as present in polybromo and yeast RSC1/2. The human polybromo protein (BAF180) is a component of the SWI/SNF chromatin-remodeling complex PBAF. It is thought that polybromo participates in transcriptional ...

  10. NM_001366073.2 → NP_001353002.1  protein polybromo-1 isoform 12

    Status: REVIEWED

    Source sequence(s)
    AC104446, AC112215
    UniProtKB/TrEMBL
    E7EVG2
    Conserved Domains (8) summary
    cd05515
    Location:676 → 780
    Bromo_polybromo_V; Bromodomain, polybromo repeat V. Polybromo is a nuclear protein of unknown function, which contains 6 bromodomains. The human ortholog BAF180 is part of a SWI/SNF chromatin-remodeling complex, and it may carry out the functions of Yeast Rsc-1 and Rsc-2. ...
    cd05517
    Location:200 → 302
    Bromo_polybromo_II; Bromodomain, polybromo repeat II. Polybromo is a nuclear protein of unknown function, which contains 6 bromodomains. The human ortholog BAF180 is part of a SWI/SNF chromatin-remodeling complex, and it may carry out the functions of Yeast Rsc-1 and Rsc-2. ...
    cd05518
    Location:537 → 640
    Bromo_polybromo_IV; Bromodomain, polybromo repeat IV. Polybromo is a nuclear protein of unknown function, which contains 6 bromodomains. The human ortholog BAF180 is part of a SWI/SNF chromatin-remodeling complex, and it may carry out the functions of Yeast Rsc-1 and Rsc-2. ...
    cd05520
    Location:401 → 502
    Bromo_polybromo_III; Bromodomain, polybromo repeat III. Polybromo is a nuclear protein of unknown function, which contains 6 bromodomains. The human ortholog BAF180 is part of a SWI/SNF chromatin-remodeling complex, and it may carry out the functions of Yeast Rsc-1 and Rsc-2. ...
    cd05524
    Location:62 → 174
    Bromo_polybromo_I; Bromodomain, polybromo repeat I. Polybromo is a nuclear protein of unknown function, which contains 6 bromodomains. The human ortholog BAF180 is part of a SWI/SNF chromatin-remodeling complex, and it may carry out the functions of Yeast Rsc-1 and Rsc-2. ...
    cd05526
    Location:793 → 900
    Bromo_polybromo_VI; Bromodomain, polybromo repeat VI. Polybromo is a nuclear protein of unknown function, which contains 6 bromodomains. The human ortholog BAF180 is part of a SWI/SNF chromatin-remodeling complex, and it may carry out the functions of Yeast Rsc-1 and Rsc-2. ...
    cd00084
    Location:1398 → 1447
    HMG-box; High Mobility Group (HMG)-box is found in a variety of eukaryotic chromosomal proteins and transcription factors. HMGs bind to the minor groove of DNA and have been classified by DNA binding preferences. Two phylogenically distinct groups of Class I ...
    cd04717
    Location:975 → 1092
    BAH_polybromo; BAH, or Bromo Adjacent Homology domain, as present in polybromo and yeast RSC1/2. The human polybromo protein (BAF180) is a component of the SWI/SNF chromatin-remodeling complex PBAF. It is thought that polybromo participates in transcriptional ...

  11. NM_001366074.2 → NP_001353003.1  protein polybromo-1 isoform 13

    Status: REVIEWED

    Source sequence(s)
    AC104446, AC112215
    UniProtKB/TrEMBL
    E7EVG2
    Conserved Domains (8) summary
    cd05515
    Location:675 → 779
    Bromo_polybromo_V; Bromodomain, polybromo repeat V. Polybromo is a nuclear protein of unknown function, which contains 6 bromodomains. The human ortholog BAF180 is part of a SWI/SNF chromatin-remodeling complex, and it may carry out the functions of Yeast Rsc-1 and Rsc-2. ...
    cd05517
    Location:199 → 301
    Bromo_polybromo_II; Bromodomain, polybromo repeat II. Polybromo is a nuclear protein of unknown function, which contains 6 bromodomains. The human ortholog BAF180 is part of a SWI/SNF chromatin-remodeling complex, and it may carry out the functions of Yeast Rsc-1 and Rsc-2. ...
    cd05518
    Location:536 → 639
    Bromo_polybromo_IV; Bromodomain, polybromo repeat IV. Polybromo is a nuclear protein of unknown function, which contains 6 bromodomains. The human ortholog BAF180 is part of a SWI/SNF chromatin-remodeling complex, and it may carry out the functions of Yeast Rsc-1 and Rsc-2. ...
    cd05520
    Location:400 → 501
    Bromo_polybromo_III; Bromodomain, polybromo repeat III. Polybromo is a nuclear protein of unknown function, which contains 6 bromodomains. The human ortholog BAF180 is part of a SWI/SNF chromatin-remodeling complex, and it may carry out the functions of Yeast Rsc-1 and Rsc-2. ...
    cd05524
    Location:61 → 173
    Bromo_polybromo_I; Bromodomain, polybromo repeat I. Polybromo is a nuclear protein of unknown function, which contains 6 bromodomains. The human ortholog BAF180 is part of a SWI/SNF chromatin-remodeling complex, and it may carry out the functions of Yeast Rsc-1 and Rsc-2. ...
    cd05526
    Location:792 → 899
    Bromo_polybromo_VI; Bromodomain, polybromo repeat VI. Polybromo is a nuclear protein of unknown function, which contains 6 bromodomains. The human ortholog BAF180 is part of a SWI/SNF chromatin-remodeling complex, and it may carry out the functions of Yeast Rsc-1 and Rsc-2. ...
    cd00084
    Location:1397 → 1446
    HMG-box; High Mobility Group (HMG)-box is found in a variety of eukaryotic chromosomal proteins and transcription factors. HMGs bind to the minor groove of DNA and have been classified by DNA binding preferences. Two phylogenically distinct groups of Class I ...
    cd04717
    Location:974 → 1091
    BAH_polybromo; BAH, or Bromo Adjacent Homology domain, as present in polybromo and yeast RSC1/2. The human polybromo protein (BAF180) is a component of the SWI/SNF chromatin-remodeling complex PBAF. It is thought that polybromo participates in transcriptional ...

  12. NM_001366075.2 → NP_001353004.1  protein polybromo-1 isoform 14

    Status: REVIEWED

    Source sequence(s)
    AC104446, AC112215
    UniProtKB/TrEMBL
    E7EVG2
    Conserved Domains (9) summary
    cd05515
    Location:694 → 798
    Bromo_polybromo_V; Bromodomain, polybromo repeat V. Polybromo is a nuclear protein of unknown function, which contains 6 bromodomains. The human ortholog BAF180 is part of a SWI/SNF chromatin-remodeling complex, and it may carry out the functions of Yeast Rsc-1 and Rsc-2. ...
    cd05517
    Location:203 → 305
    Bromo_polybromo_II; Bromodomain, polybromo repeat II. Polybromo is a nuclear protein of unknown function, which contains 6 bromodomains. The human ortholog BAF180 is part of a SWI/SNF chromatin-remodeling complex, and it may carry out the functions of Yeast Rsc-1 and Rsc-2. ...
    cd05518
    Location:555 → 658
    Bromo_polybromo_IV; Bromodomain, polybromo repeat IV. Polybromo is a nuclear protein of unknown function, which contains 6 bromodomains. The human ortholog BAF180 is part of a SWI/SNF chromatin-remodeling complex, and it may carry out the functions of Yeast Rsc-1 and Rsc-2. ...
    cd05520
    Location:404 → 505
    Bromo_polybromo_III; Bromodomain, polybromo repeat III. Polybromo is a nuclear protein of unknown function, which contains 6 bromodomains. The human ortholog BAF180 is part of a SWI/SNF chromatin-remodeling complex, and it may carry out the functions of Yeast Rsc-1 and Rsc-2. ...
    cd05524
    Location:65 → 177
    Bromo_polybromo_I; Bromodomain, polybromo repeat I. Polybromo is a nuclear protein of unknown function, which contains 6 bromodomains. The human ortholog BAF180 is part of a SWI/SNF chromatin-remodeling complex, and it may carry out the functions of Yeast Rsc-1 and Rsc-2. ...
    cd05526
    Location:811 → 918
    Bromo_polybromo_VI; Bromodomain, polybromo repeat VI. Polybromo is a nuclear protein of unknown function, which contains 6 bromodomains. The human ortholog BAF180 is part of a SWI/SNF chromatin-remodeling complex, and it may carry out the functions of Yeast Rsc-1 and Rsc-2. ...
    cd00084
    Location:1391 → 1440
    HMG-box; High Mobility Group (HMG)-box is found in a variety of eukaryotic chromosomal proteins and transcription factors. HMGs bind to the minor groove of DNA and have been classified by DNA binding preferences. Two phylogenically distinct groups of Class I ...
    cd04717
    Location:1166 → 1284
    BAH_polybromo; BAH, or Bromo Adjacent Homology domain, as present in polybromo and yeast RSC1/2. The human polybromo protein (BAF180) is a component of the SWI/SNF chromatin-remodeling complex PBAF. It is thought that polybromo participates in transcriptional ...
    cl02608
    Location:993 → 1085
    BAH; or Bromo Adjacent Homology domain (also called ELM1 and BAM for Bromo Adjacent Motif). BAH domains have first been described as domains found in the polybromo protein and Yeast Rsc1/Rsc2 (Remodeling of the Structure of Chromatin). They also occur in ...

  13. NM_001366076.2 → NP_001353005.1  protein polybromo-1 isoform 15

    Status: REVIEWED

    Source sequence(s)
    AC104446, AC112215
    UniProtKB/TrEMBL
    E7EVG2
    Conserved Domains (8) summary
    cd05515
    Location:659 → 763
    Bromo_polybromo_V; Bromodomain, polybromo repeat V. Polybromo is a nuclear protein of unknown function, which contains 6 bromodomains. The human ortholog BAF180 is part of a SWI/SNF chromatin-remodeling complex, and it may carry out the functions of Yeast Rsc-1 and Rsc-2. ...
    cd05517
    Location:200 → 302
    Bromo_polybromo_II; Bromodomain, polybromo repeat II. Polybromo is a nuclear protein of unknown function, which contains 6 bromodomains. The human ortholog BAF180 is part of a SWI/SNF chromatin-remodeling complex, and it may carry out the functions of Yeast Rsc-1 and Rsc-2. ...
    cd05518
    Location:520 → 623
    Bromo_polybromo_IV; Bromodomain, polybromo repeat IV. Polybromo is a nuclear protein of unknown function, which contains 6 bromodomains. The human ortholog BAF180 is part of a SWI/SNF chromatin-remodeling complex, and it may carry out the functions of Yeast Rsc-1 and Rsc-2. ...
    cd05520
    Location:369 → 470
    Bromo_polybromo_III; Bromodomain, polybromo repeat III. Polybromo is a nuclear protein of unknown function, which contains 6 bromodomains. The human ortholog BAF180 is part of a SWI/SNF chromatin-remodeling complex, and it may carry out the functions of Yeast Rsc-1 and Rsc-2. ...
    cd05524
    Location:62 → 174
    Bromo_polybromo_I; Bromodomain, polybromo repeat I. Polybromo is a nuclear protein of unknown function, which contains 6 bromodomains. The human ortholog BAF180 is part of a SWI/SNF chromatin-remodeling complex, and it may carry out the functions of Yeast Rsc-1 and Rsc-2. ...
    cd05526
    Location:776 → 883
    Bromo_polybromo_VI; Bromodomain, polybromo repeat VI. Polybromo is a nuclear protein of unknown function, which contains 6 bromodomains. The human ortholog BAF180 is part of a SWI/SNF chromatin-remodeling complex, and it may carry out the functions of Yeast Rsc-1 and Rsc-2. ...
    cd00084
    Location:1381 → 1430
    HMG-box; High Mobility Group (HMG)-box is found in a variety of eukaryotic chromosomal proteins and transcription factors. HMGs bind to the minor groove of DNA and have been classified by DNA binding preferences. Two phylogenically distinct groups of Class I ...
    cd04717
    Location:958 → 1075
    BAH_polybromo; BAH, or Bromo Adjacent Homology domain, as present in polybromo and yeast RSC1/2. The human polybromo protein (BAF180) is a component of the SWI/SNF chromatin-remodeling complex PBAF. It is thought that polybromo participates in transcriptional ...

  14. NM_001394867.1 → NP_001381796.1  protein polybromo-1 isoform 16

    Status: REVIEWED

    Source sequence(s)
    AC104446, AC112215
    Consensus CDS
    CCDS93286.1
    UniProtKB/Swiss-Prot
    A1L381, A1L382, A4FUJ7, Q1RMD1, Q1RMD2, Q86U86, Q96MS2, Q9H2T3, Q9H2T4, Q9H2T5, Q9H301, Q9H314
    UniProtKB/TrEMBL
    E7EVG2
    Conserved Domains (8) summary
    cd05515
    Location:658 → 762
    Bromo_polybromo_V; Bromodomain, polybromo repeat V. Polybromo is a nuclear protein of unknown function, which contains 6 bromodomains. The human ortholog BAF180 is part of a SWI/SNF chromatin-remodeling complex, and it may carry out the functions of Yeast Rsc-1 and Rsc-2. ...
    cd05517
    Location:182 → 284
    Bromo_polybromo_II; Bromodomain, polybromo repeat II. Polybromo is a nuclear protein of unknown function, which contains 6 bromodomains. The human ortholog BAF180 is part of a SWI/SNF chromatin-remodeling complex, and it may carry out the functions of Yeast Rsc-1 and Rsc-2. ...
    cd05518
    Location:519 → 622
    Bromo_polybromo_IV; Bromodomain, polybromo repeat IV. Polybromo is a nuclear protein of unknown function, which contains 6 bromodomains. The human ortholog BAF180 is part of a SWI/SNF chromatin-remodeling complex, and it may carry out the functions of Yeast Rsc-1 and Rsc-2. ...
    cd05520
    Location:383 → 484
    Bromo_polybromo_III; Bromodomain, polybromo repeat III. Polybromo is a nuclear protein of unknown function, which contains 6 bromodomains. The human ortholog BAF180 is part of a SWI/SNF chromatin-remodeling complex, and it may carry out the functions of Yeast Rsc-1 and Rsc-2. ...
    cd05524
    Location:44 → 156
    Bromo_polybromo_I; Bromodomain, polybromo repeat I. Polybromo is a nuclear protein of unknown function, which contains 6 bromodomains. The human ortholog BAF180 is part of a SWI/SNF chromatin-remodeling complex, and it may carry out the functions of Yeast Rsc-1 and Rsc-2. ...
    cd05526
    Location:775 → 882
    Bromo_polybromo_VI; Bromodomain, polybromo repeat VI. Polybromo is a nuclear protein of unknown function, which contains 6 bromodomains. The human ortholog BAF180 is part of a SWI/SNF chromatin-remodeling complex, and it may carry out the functions of Yeast Rsc-1 and Rsc-2. ...
    cd00084
    Location:1380 → 1444
    HMG-box; High Mobility Group (HMG)-box is found in a variety of eukaryotic chromosomal proteins and transcription factors. HMGs bind to the minor groove of DNA and have been classified by DNA binding preferences. Two phylogenically distinct groups of Class I ...
    cd04717
    Location:957 → 1074
    BAH_polybromo; BAH, or Bromo Adjacent Homology domain, as present in polybromo and yeast RSC1/2. The human polybromo protein (BAF180) is a component of the SWI/SNF chromatin-remodeling complex PBAF. It is thought that polybromo participates in transcriptional ...

  15. NM_001394868.1 → NP_001381797.1  protein polybromo-1 isoform 16

    Status: REVIEWED

    Source sequence(s)
    AC104446, AC112215
    Consensus CDS
    CCDS93286.1
    UniProtKB/Swiss-Prot
    A1L381, A1L382, A4FUJ7, Q1RMD1, Q1RMD2, Q86U86, Q96MS2, Q9H2T3, Q9H2T4, Q9H2T5, Q9H301, Q9H314
    UniProtKB/TrEMBL
    E7EVG2
    Conserved Domains (8) summary
    cd05515
    Location:658 → 762
    Bromo_polybromo_V; Bromodomain, polybromo repeat V. Polybromo is a nuclear protein of unknown function, which contains 6 bromodomains. The human ortholog BAF180 is part of a SWI/SNF chromatin-remodeling complex, and it may carry out the functions of Yeast Rsc-1 and Rsc-2. ...
    cd05517
    Location:182 → 284
    Bromo_polybromo_II; Bromodomain, polybromo repeat II. Polybromo is a nuclear protein of unknown function, which contains 6 bromodomains. The human ortholog BAF180 is part of a SWI/SNF chromatin-remodeling complex, and it may carry out the functions of Yeast Rsc-1 and Rsc-2. ...
    cd05518
    Location:519 → 622
    Bromo_polybromo_IV; Bromodomain, polybromo repeat IV. Polybromo is a nuclear protein of unknown function, which contains 6 bromodomains. The human ortholog BAF180 is part of a SWI/SNF chromatin-remodeling complex, and it may carry out the functions of Yeast Rsc-1 and Rsc-2. ...
    cd05520
    Location:383 → 484
    Bromo_polybromo_III; Bromodomain, polybromo repeat III. Polybromo is a nuclear protein of unknown function, which contains 6 bromodomains. The human ortholog BAF180 is part of a SWI/SNF chromatin-remodeling complex, and it may carry out the functions of Yeast Rsc-1 and Rsc-2. ...
    cd05524
    Location:44 → 156
    Bromo_polybromo_I; Bromodomain, polybromo repeat I. Polybromo is a nuclear protein of unknown function, which contains 6 bromodomains. The human ortholog BAF180 is part of a SWI/SNF chromatin-remodeling complex, and it may carry out the functions of Yeast Rsc-1 and Rsc-2. ...
    cd05526
    Location:775 → 882
    Bromo_polybromo_VI; Bromodomain, polybromo repeat VI. Polybromo is a nuclear protein of unknown function, which contains 6 bromodomains. The human ortholog BAF180 is part of a SWI/SNF chromatin-remodeling complex, and it may carry out the functions of Yeast Rsc-1 and Rsc-2. ...
    cd00084
    Location:1380 → 1444
    HMG-box; High Mobility Group (HMG)-box is found in a variety of eukaryotic chromosomal proteins and transcription factors. HMGs bind to the minor groove of DNA and have been classified by DNA binding preferences. Two phylogenically distinct groups of Class I ...
    cd04717
    Location:957 → 1074
    BAH_polybromo; BAH, or Bromo Adjacent Homology domain, as present in polybromo and yeast RSC1/2. The human polybromo protein (BAF180) is a component of the SWI/SNF chromatin-remodeling complex PBAF. It is thought that polybromo participates in transcriptional ...

  16. NM_001394869.1 → NP_001381798.1  protein polybromo-1 isoform 16

    Status: REVIEWED

    Source sequence(s)
    AC104446, AC112215
    Consensus CDS
    CCDS93286.1
    UniProtKB/Swiss-Prot
    A1L381, A1L382, A4FUJ7, Q1RMD1, Q1RMD2, Q86U86, Q96MS2, Q9H2T3, Q9H2T4, Q9H2T5, Q9H301, Q9H314
    UniProtKB/TrEMBL
    E7EVG2
    Conserved Domains (8) summary
    cd05515
    Location:658 → 762
    Bromo_polybromo_V; Bromodomain, polybromo repeat V. Polybromo is a nuclear protein of unknown function, which contains 6 bromodomains. The human ortholog BAF180 is part of a SWI/SNF chromatin-remodeling complex, and it may carry out the functions of Yeast Rsc-1 and Rsc-2. ...
    cd05517
    Location:182 → 284
    Bromo_polybromo_II; Bromodomain, polybromo repeat II. Polybromo is a nuclear protein of unknown function, which contains 6 bromodomains. The human ortholog BAF180 is part of a SWI/SNF chromatin-remodeling complex, and it may carry out the functions of Yeast Rsc-1 and Rsc-2. ...
    cd05518
    Location:519 → 622
    Bromo_polybromo_IV; Bromodomain, polybromo repeat IV. Polybromo is a nuclear protein of unknown function, which contains 6 bromodomains. The human ortholog BAF180 is part of a SWI/SNF chromatin-remodeling complex, and it may carry out the functions of Yeast Rsc-1 and Rsc-2. ...
    cd05520
    Location:383 → 484
    Bromo_polybromo_III; Bromodomain, polybromo repeat III. Polybromo is a nuclear protein of unknown function, which contains 6 bromodomains. The human ortholog BAF180 is part of a SWI/SNF chromatin-remodeling complex, and it may carry out the functions of Yeast Rsc-1 and Rsc-2. ...
    cd05524
    Location:44 → 156
    Bromo_polybromo_I; Bromodomain, polybromo repeat I. Polybromo is a nuclear protein of unknown function, which contains 6 bromodomains. The human ortholog BAF180 is part of a SWI/SNF chromatin-remodeling complex, and it may carry out the functions of Yeast Rsc-1 and Rsc-2. ...
    cd05526
    Location:775 → 882
    Bromo_polybromo_VI; Bromodomain, polybromo repeat VI. Polybromo is a nuclear protein of unknown function, which contains 6 bromodomains. The human ortholog BAF180 is part of a SWI/SNF chromatin-remodeling complex, and it may carry out the functions of Yeast Rsc-1 and Rsc-2. ...
    cd00084
    Location:1380 → 1444
    HMG-box; High Mobility Group (HMG)-box is found in a variety of eukaryotic chromosomal proteins and transcription factors. HMGs bind to the minor groove of DNA and have been classified by DNA binding preferences. Two phylogenically distinct groups of Class I ...
    cd04717
    Location:957 → 1074
    BAH_polybromo; BAH, or Bromo Adjacent Homology domain, as present in polybromo and yeast RSC1/2. The human polybromo protein (BAF180) is a component of the SWI/SNF chromatin-remodeling complex PBAF. It is thought that polybromo participates in transcriptional ...

  17. NM_001394870.1 → NP_001381799.1  protein polybromo-1 isoform 17

    Status: REVIEWED

    Source sequence(s)
    AC104446, AC112215
    UniProtKB/TrEMBL
    E7EVG2
    Conserved Domains (8) summary
    cd05515
    Location:676 → 780
    Bromo_polybromo_V; Bromodomain, polybromo repeat V. Polybromo is a nuclear protein of unknown function, which contains 6 bromodomains. The human ortholog BAF180 is part of a SWI/SNF chromatin-remodeling complex, and it may carry out the functions of Yeast Rsc-1 and Rsc-2. ...
    cd05517
    Location:200 → 302
    Bromo_polybromo_II; Bromodomain, polybromo repeat II. Polybromo is a nuclear protein of unknown function, which contains 6 bromodomains. The human ortholog BAF180 is part of a SWI/SNF chromatin-remodeling complex, and it may carry out the functions of Yeast Rsc-1 and Rsc-2. ...
    cd05518
    Location:537 → 640
    Bromo_polybromo_IV; Bromodomain, polybromo repeat IV. Polybromo is a nuclear protein of unknown function, which contains 6 bromodomains. The human ortholog BAF180 is part of a SWI/SNF chromatin-remodeling complex, and it may carry out the functions of Yeast Rsc-1 and Rsc-2. ...
    cd05520
    Location:401 → 502
    Bromo_polybromo_III; Bromodomain, polybromo repeat III. Polybromo is a nuclear protein of unknown function, which contains 6 bromodomains. The human ortholog BAF180 is part of a SWI/SNF chromatin-remodeling complex, and it may carry out the functions of Yeast Rsc-1 and Rsc-2. ...
    cd05524
    Location:62 → 174
    Bromo_polybromo_I; Bromodomain, polybromo repeat I. Polybromo is a nuclear protein of unknown function, which contains 6 bromodomains. The human ortholog BAF180 is part of a SWI/SNF chromatin-remodeling complex, and it may carry out the functions of Yeast Rsc-1 and Rsc-2. ...
    cd05526
    Location:793 → 900
    Bromo_polybromo_VI; Bromodomain, polybromo repeat VI. Polybromo is a nuclear protein of unknown function, which contains 6 bromodomains. The human ortholog BAF180 is part of a SWI/SNF chromatin-remodeling complex, and it may carry out the functions of Yeast Rsc-1 and Rsc-2. ...
    cd00084
    Location:1398 → 1447
    HMG-box; High Mobility Group (HMG)-box is found in a variety of eukaryotic chromosomal proteins and transcription factors. HMGs bind to the minor groove of DNA and have been classified by DNA binding preferences. Two phylogenically distinct groups of Class I ...
    cd04717
    Location:975 → 1092
    BAH_polybromo; BAH, or Bromo Adjacent Homology domain, as present in polybromo and yeast RSC1/2. The human polybromo protein (BAF180) is a component of the SWI/SNF chromatin-remodeling complex PBAF. It is thought that polybromo participates in transcriptional ...

  18. NM_001394871.1 → NP_001381800.1  protein polybromo-1 isoform 18

    Status: REVIEWED

    Source sequence(s)
    AC104446, AC112215
    UniProtKB/TrEMBL
    E7EVG2
    Conserved Domains (9) summary
    cd05515
    Location:658 → 762
    Bromo_polybromo_V; Bromodomain, polybromo repeat V. Polybromo is a nuclear protein of unknown function, which contains 6 bromodomains. The human ortholog BAF180 is part of a SWI/SNF chromatin-remodeling complex, and it may carry out the functions of Yeast Rsc-1 and Rsc-2. ...
    cd05517
    Location:182 → 284
    Bromo_polybromo_II; Bromodomain, polybromo repeat II. Polybromo is a nuclear protein of unknown function, which contains 6 bromodomains. The human ortholog BAF180 is part of a SWI/SNF chromatin-remodeling complex, and it may carry out the functions of Yeast Rsc-1 and Rsc-2. ...
    cd05518
    Location:519 → 622
    Bromo_polybromo_IV; Bromodomain, polybromo repeat IV. Polybromo is a nuclear protein of unknown function, which contains 6 bromodomains. The human ortholog BAF180 is part of a SWI/SNF chromatin-remodeling complex, and it may carry out the functions of Yeast Rsc-1 and Rsc-2. ...
    cd05520
    Location:383 → 484
    Bromo_polybromo_III; Bromodomain, polybromo repeat III. Polybromo is a nuclear protein of unknown function, which contains 6 bromodomains. The human ortholog BAF180 is part of a SWI/SNF chromatin-remodeling complex, and it may carry out the functions of Yeast Rsc-1 and Rsc-2. ...
    cd05524
    Location:44 → 156
    Bromo_polybromo_I; Bromodomain, polybromo repeat I. Polybromo is a nuclear protein of unknown function, which contains 6 bromodomains. The human ortholog BAF180 is part of a SWI/SNF chromatin-remodeling complex, and it may carry out the functions of Yeast Rsc-1 and Rsc-2. ...
    cd05526
    Location:775 → 882
    Bromo_polybromo_VI; Bromodomain, polybromo repeat VI. Polybromo is a nuclear protein of unknown function, which contains 6 bromodomains. The human ortholog BAF180 is part of a SWI/SNF chromatin-remodeling complex, and it may carry out the functions of Yeast Rsc-1 and Rsc-2. ...
    PRK06302
    Location:1444 → 1509
    PRK06302; acetyl-CoA carboxylase biotin carboxyl carrier protein
    cd00084
    Location:1380 → 1444
    HMG-box; High Mobility Group (HMG)-box is found in a variety of eukaryotic chromosomal proteins and transcription factors. HMGs bind to the minor groove of DNA and have been classified by DNA binding preferences. Two phylogenically distinct groups of Class I ...
    cd04717
    Location:957 → 1074
    BAH_polybromo; BAH, or Bromo Adjacent Homology domain, as present in polybromo and yeast RSC1/2. The human polybromo protein (BAF180) is a component of the SWI/SNF chromatin-remodeling complex PBAF. It is thought that polybromo participates in transcriptional ...

  19. NM_001394872.1 → NP_001381801.1  protein polybromo-1 isoform 6

    Status: REVIEWED

    Source sequence(s)
    AC104446, AC112215
    Consensus CDS
    CCDS87087.1
    UniProtKB/TrEMBL
    E7EVG2
    Conserved Domains (8) summary
    cd05515
    Location:658 → 762
    Bromo_polybromo_V; Bromodomain, polybromo repeat V. Polybromo is a nuclear protein of unknown function, which contains 6 bromodomains. The human ortholog BAF180 is part of a SWI/SNF chromatin-remodeling complex, and it may carry out the functions of Yeast Rsc-1 and Rsc-2. ...
    cd05517
    Location:182 → 284
    Bromo_polybromo_II; Bromodomain, polybromo repeat II. Polybromo is a nuclear protein of unknown function, which contains 6 bromodomains. The human ortholog BAF180 is part of a SWI/SNF chromatin-remodeling complex, and it may carry out the functions of Yeast Rsc-1 and Rsc-2. ...
    cd05518
    Location:519 → 622
    Bromo_polybromo_IV; Bromodomain, polybromo repeat IV. Polybromo is a nuclear protein of unknown function, which contains 6 bromodomains. The human ortholog BAF180 is part of a SWI/SNF chromatin-remodeling complex, and it may carry out the functions of Yeast Rsc-1 and Rsc-2. ...
    cd05520
    Location:383 → 484
    Bromo_polybromo_III; Bromodomain, polybromo repeat III. Polybromo is a nuclear protein of unknown function, which contains 6 bromodomains. The human ortholog BAF180 is part of a SWI/SNF chromatin-remodeling complex, and it may carry out the functions of Yeast Rsc-1 and Rsc-2. ...
    cd05524
    Location:44 → 156
    Bromo_polybromo_I; Bromodomain, polybromo repeat I. Polybromo is a nuclear protein of unknown function, which contains 6 bromodomains. The human ortholog BAF180 is part of a SWI/SNF chromatin-remodeling complex, and it may carry out the functions of Yeast Rsc-1 and Rsc-2. ...
    cd05526
    Location:775 → 882
    Bromo_polybromo_VI; Bromodomain, polybromo repeat VI. Polybromo is a nuclear protein of unknown function, which contains 6 bromodomains. The human ortholog BAF180 is part of a SWI/SNF chromatin-remodeling complex, and it may carry out the functions of Yeast Rsc-1 and Rsc-2. ...
    cd00084
    Location:1380 → 1429
    HMG-box; High Mobility Group (HMG)-box is found in a variety of eukaryotic chromosomal proteins and transcription factors. HMGs bind to the minor groove of DNA and have been classified by DNA binding preferences. Two phylogenically distinct groups of Class I ...
    cd04717
    Location:957 → 1074
    BAH_polybromo; BAH, or Bromo Adjacent Homology domain, as present in polybromo and yeast RSC1/2. The human polybromo protein (BAF180) is a component of the SWI/SNF chromatin-remodeling complex PBAF. It is thought that polybromo participates in transcriptional ...

  20. NM_001394873.1 → NP_001381802.1  protein polybromo-1 isoform 20

    Status: REVIEWED

    Source sequence(s)
    AC104446, AC112215
    UniProtKB/TrEMBL
    E7EVG2
    Conserved Domains (8) summary
    cd05515
    Location:658 → 762
    Bromo_polybromo_V; Bromodomain, polybromo repeat V. Polybromo is a nuclear protein of unknown function, which contains 6 bromodomains. The human ortholog BAF180 is part of a SWI/SNF chromatin-remodeling complex, and it may carry out the functions of Yeast Rsc-1 and Rsc-2. ...
    cd05517
    Location:182 → 284
    Bromo_polybromo_II; Bromodomain, polybromo repeat II. Polybromo is a nuclear protein of unknown function, which contains 6 bromodomains. The human ortholog BAF180 is part of a SWI/SNF chromatin-remodeling complex, and it may carry out the functions of Yeast Rsc-1 and Rsc-2. ...
    cd05518
    Location:519 → 622
    Bromo_polybromo_IV; Bromodomain, polybromo repeat IV. Polybromo is a nuclear protein of unknown function, which contains 6 bromodomains. The human ortholog BAF180 is part of a SWI/SNF chromatin-remodeling complex, and it may carry out the functions of Yeast Rsc-1 and Rsc-2. ...
    cd05520
    Location:383 → 484
    Bromo_polybromo_III; Bromodomain, polybromo repeat III. Polybromo is a nuclear protein of unknown function, which contains 6 bromodomains. The human ortholog BAF180 is part of a SWI/SNF chromatin-remodeling complex, and it may carry out the functions of Yeast Rsc-1 and Rsc-2. ...
    cd05524
    Location:44 → 156
    Bromo_polybromo_I; Bromodomain, polybromo repeat I. Polybromo is a nuclear protein of unknown function, which contains 6 bromodomains. The human ortholog BAF180 is part of a SWI/SNF chromatin-remodeling complex, and it may carry out the functions of Yeast Rsc-1 and Rsc-2. ...
    cd05526
    Location:775 → 882
    Bromo_polybromo_VI; Bromodomain, polybromo repeat VI. Polybromo is a nuclear protein of unknown function, which contains 6 bromodomains. The human ortholog BAF180 is part of a SWI/SNF chromatin-remodeling complex, and it may carry out the functions of Yeast Rsc-1 and Rsc-2. ...
    cd00084
    Location:1379 → 1428
    HMG-box; High Mobility Group (HMG)-box is found in a variety of eukaryotic chromosomal proteins and transcription factors. HMGs bind to the minor groove of DNA and have been classified by DNA binding preferences. Two phylogenically distinct groups of Class I ...
    cd04717
    Location:956 → 1073
    BAH_polybromo; BAH, or Bromo Adjacent Homology domain, as present in polybromo and yeast RSC1/2. The human polybromo protein (BAF180) is a component of the SWI/SNF chromatin-remodeling complex PBAF. It is thought that polybromo participates in transcriptional ...

  21. NM_001394874.1 → NP_001381803.1  protein polybromo-1 isoform 20

    Status: REVIEWED

    Source sequence(s)
    AC104446, AC112215
    UniProtKB/TrEMBL
    E7EVG2
    Conserved Domains (8) summary
    cd05515
    Location:658 → 762
    Bromo_polybromo_V; Bromodomain, polybromo repeat V. Polybromo is a nuclear protein of unknown function, which contains 6 bromodomains. The human ortholog BAF180 is part of a SWI/SNF chromatin-remodeling complex, and it may carry out the functions of Yeast Rsc-1 and Rsc-2. ...
    cd05517
    Location:182 → 284
    Bromo_polybromo_II; Bromodomain, polybromo repeat II. Polybromo is a nuclear protein of unknown function, which contains 6 bromodomains. The human ortholog BAF180 is part of a SWI/SNF chromatin-remodeling complex, and it may carry out the functions of Yeast Rsc-1 and Rsc-2. ...
    cd05518
    Location:519 → 622
    Bromo_polybromo_IV; Bromodomain, polybromo repeat IV. Polybromo is a nuclear protein of unknown function, which contains 6 bromodomains. The human ortholog BAF180 is part of a SWI/SNF chromatin-remodeling complex, and it may carry out the functions of Yeast Rsc-1 and Rsc-2. ...
    cd05520
    Location:383 → 484
    Bromo_polybromo_III; Bromodomain, polybromo repeat III. Polybromo is a nuclear protein of unknown function, which contains 6 bromodomains. The human ortholog BAF180 is part of a SWI/SNF chromatin-remodeling complex, and it may carry out the functions of Yeast Rsc-1 and Rsc-2. ...
    cd05524
    Location:44 → 156
    Bromo_polybromo_I; Bromodomain, polybromo repeat I. Polybromo is a nuclear protein of unknown function, which contains 6 bromodomains. The human ortholog BAF180 is part of a SWI/SNF chromatin-remodeling complex, and it may carry out the functions of Yeast Rsc-1 and Rsc-2. ...
    cd05526
    Location:775 → 882
    Bromo_polybromo_VI; Bromodomain, polybromo repeat VI. Polybromo is a nuclear protein of unknown function, which contains 6 bromodomains. The human ortholog BAF180 is part of a SWI/SNF chromatin-remodeling complex, and it may carry out the functions of Yeast Rsc-1 and Rsc-2. ...
    cd00084
    Location:1379 → 1428
    HMG-box; High Mobility Group (HMG)-box is found in a variety of eukaryotic chromosomal proteins and transcription factors. HMGs bind to the minor groove of DNA and have been classified by DNA binding preferences. Two phylogenically distinct groups of Class I ...
    cd04717
    Location:956 → 1073
    BAH_polybromo; BAH, or Bromo Adjacent Homology domain, as present in polybromo and yeast RSC1/2. The human polybromo protein (BAF180) is a component of the SWI/SNF chromatin-remodeling complex PBAF. It is thought that polybromo participates in transcriptional ...

  22. NM_001394875.1 → NP_001381804.1  protein polybromo-1 isoform 4

    Status: REVIEWED

    Source sequence(s)
    AC104446, AC112215
    Consensus CDS
    CCDS2860.1
    UniProtKB/TrEMBL
    E7EVG2
    Conserved Domains (8) summary
    cd05515
    Location:658 → 762
    Bromo_polybromo_V; Bromodomain, polybromo repeat V. Polybromo is a nuclear protein of unknown function, which contains 6 bromodomains. The human ortholog BAF180 is part of a SWI/SNF chromatin-remodeling complex, and it may carry out the functions of Yeast Rsc-1 and Rsc-2. ...
    cd05517
    Location:182 → 284
    Bromo_polybromo_II; Bromodomain, polybromo repeat II. Polybromo is a nuclear protein of unknown function, which contains 6 bromodomains. The human ortholog BAF180 is part of a SWI/SNF chromatin-remodeling complex, and it may carry out the functions of Yeast Rsc-1 and Rsc-2. ...
    cd05518
    Location:519 → 622
    Bromo_polybromo_IV; Bromodomain, polybromo repeat IV. Polybromo is a nuclear protein of unknown function, which contains 6 bromodomains. The human ortholog BAF180 is part of a SWI/SNF chromatin-remodeling complex, and it may carry out the functions of Yeast Rsc-1 and Rsc-2. ...
    cd05520
    Location:383 → 484
    Bromo_polybromo_III; Bromodomain, polybromo repeat III. Polybromo is a nuclear protein of unknown function, which contains 6 bromodomains. The human ortholog BAF180 is part of a SWI/SNF chromatin-remodeling complex, and it may carry out the functions of Yeast Rsc-1 and Rsc-2. ...
    cd05524
    Location:44 → 156
    Bromo_polybromo_I; Bromodomain, polybromo repeat I. Polybromo is a nuclear protein of unknown function, which contains 6 bromodomains. The human ortholog BAF180 is part of a SWI/SNF chromatin-remodeling complex, and it may carry out the functions of Yeast Rsc-1 and Rsc-2. ...
    cd05526
    Location:775 → 882
    Bromo_polybromo_VI; Bromodomain, polybromo repeat VI. Polybromo is a nuclear protein of unknown function, which contains 6 bromodomains. The human ortholog BAF180 is part of a SWI/SNF chromatin-remodeling complex, and it may carry out the functions of Yeast Rsc-1 and Rsc-2. ...
    cd00084
    Location:1380 → 1429
    HMG-box; High Mobility Group (HMG)-box is found in a variety of eukaryotic chromosomal proteins and transcription factors. HMGs bind to the minor groove of DNA and have been classified by DNA binding preferences. Two phylogenically distinct groups of Class I ...
    cd04717
    Location:957 → 1074
    BAH_polybromo; BAH, or Bromo Adjacent Homology domain, as present in polybromo and yeast RSC1/2. The human polybromo protein (BAF180) is a component of the SWI/SNF chromatin-remodeling complex PBAF. It is thought that polybromo participates in transcriptional ...

  23. NM_001394876.1 → NP_001381805.1  protein polybromo-1 isoform 22

    Status: REVIEWED

    Source sequence(s)
    AC104446, AC112215
    UniProtKB/TrEMBL
    E7EVG2
    Conserved Domains (8) summary
    cd05515
    Location:658 → 762
    Bromo_polybromo_V; Bromodomain, polybromo repeat V. Polybromo is a nuclear protein of unknown function, which contains 6 bromodomains. The human ortholog BAF180 is part of a SWI/SNF chromatin-remodeling complex, and it may carry out the functions of Yeast Rsc-1 and Rsc-2. ...
    cd05517
    Location:182 → 284
    Bromo_polybromo_II; Bromodomain, polybromo repeat II. Polybromo is a nuclear protein of unknown function, which contains 6 bromodomains. The human ortholog BAF180 is part of a SWI/SNF chromatin-remodeling complex, and it may carry out the functions of Yeast Rsc-1 and Rsc-2. ...
    cd05518
    Location:519 → 622
    Bromo_polybromo_IV; Bromodomain, polybromo repeat IV. Polybromo is a nuclear protein of unknown function, which contains 6 bromodomains. The human ortholog BAF180 is part of a SWI/SNF chromatin-remodeling complex, and it may carry out the functions of Yeast Rsc-1 and Rsc-2. ...
    cd05520
    Location:383 → 484
    Bromo_polybromo_III; Bromodomain, polybromo repeat III. Polybromo is a nuclear protein of unknown function, which contains 6 bromodomains. The human ortholog BAF180 is part of a SWI/SNF chromatin-remodeling complex, and it may carry out the functions of Yeast Rsc-1 and Rsc-2. ...
    cd05524
    Location:44 → 156
    Bromo_polybromo_I; Bromodomain, polybromo repeat I. Polybromo is a nuclear protein of unknown function, which contains 6 bromodomains. The human ortholog BAF180 is part of a SWI/SNF chromatin-remodeling complex, and it may carry out the functions of Yeast Rsc-1 and Rsc-2. ...
    cd05526
    Location:775 → 882
    Bromo_polybromo_VI; Bromodomain, polybromo repeat VI. Polybromo is a nuclear protein of unknown function, which contains 6 bromodomains. The human ortholog BAF180 is part of a SWI/SNF chromatin-remodeling complex, and it may carry out the functions of Yeast Rsc-1 and Rsc-2. ...
    cd00084
    Location:1379 → 1428
    HMG-box; High Mobility Group (HMG)-box is found in a variety of eukaryotic chromosomal proteins and transcription factors. HMGs bind to the minor groove of DNA and have been classified by DNA binding preferences. Two phylogenically distinct groups of Class I ...
    cd04717
    Location:956 → 1073
    BAH_polybromo; BAH, or Bromo Adjacent Homology domain, as present in polybromo and yeast RSC1/2. The human polybromo protein (BAF180) is a component of the SWI/SNF chromatin-remodeling complex PBAF. It is thought that polybromo participates in transcriptional ...

  24. NM_001394877.1 → NP_001381806.1  protein polybromo-1 isoform 22

    Status: REVIEWED

    Source sequence(s)
    AC104446, AC112215
    UniProtKB/TrEMBL
    E7EVG2
    Conserved Domains (8) summary
    cd05515
    Location:658 → 762
    Bromo_polybromo_V; Bromodomain, polybromo repeat V. Polybromo is a nuclear protein of unknown function, which contains 6 bromodomains. The human ortholog BAF180 is part of a SWI/SNF chromatin-remodeling complex, and it may carry out the functions of Yeast Rsc-1 and Rsc-2. ...
    cd05517
    Location:182 → 284
    Bromo_polybromo_II; Bromodomain, polybromo repeat II. Polybromo is a nuclear protein of unknown function, which contains 6 bromodomains. The human ortholog BAF180 is part of a SWI/SNF chromatin-remodeling complex, and it may carry out the functions of Yeast Rsc-1 and Rsc-2. ...
    cd05518
    Location:519 → 622
    Bromo_polybromo_IV; Bromodomain, polybromo repeat IV. Polybromo is a nuclear protein of unknown function, which contains 6 bromodomains. The human ortholog BAF180 is part of a SWI/SNF chromatin-remodeling complex, and it may carry out the functions of Yeast Rsc-1 and Rsc-2. ...
    cd05520
    Location:383 → 484
    Bromo_polybromo_III; Bromodomain, polybromo repeat III. Polybromo is a nuclear protein of unknown function, which contains 6 bromodomains. The human ortholog BAF180 is part of a SWI/SNF chromatin-remodeling complex, and it may carry out the functions of Yeast Rsc-1 and Rsc-2. ...
    cd05524
    Location:44 → 156
    Bromo_polybromo_I; Bromodomain, polybromo repeat I. Polybromo is a nuclear protein of unknown function, which contains 6 bromodomains. The human ortholog BAF180 is part of a SWI/SNF chromatin-remodeling complex, and it may carry out the functions of Yeast Rsc-1 and Rsc-2. ...
    cd05526
    Location:775 → 882
    Bromo_polybromo_VI; Bromodomain, polybromo repeat VI. Polybromo is a nuclear protein of unknown function, which contains 6 bromodomains. The human ortholog BAF180 is part of a SWI/SNF chromatin-remodeling complex, and it may carry out the functions of Yeast Rsc-1 and Rsc-2. ...
    cd00084
    Location:1379 → 1428
    HMG-box; High Mobility Group (HMG)-box is found in a variety of eukaryotic chromosomal proteins and transcription factors. HMGs bind to the minor groove of DNA and have been classified by DNA binding preferences. Two phylogenically distinct groups of Class I ...
    cd04717
    Location:956 → 1073
    BAH_polybromo; BAH, or Bromo Adjacent Homology domain, as present in polybromo and yeast RSC1/2. The human polybromo protein (BAF180) is a component of the SWI/SNF chromatin-remodeling complex PBAF. It is thought that polybromo participates in transcriptional ...

  25. NM_001394878.1 → NP_001381807.1  protein polybromo-1 isoform 23

    Status: REVIEWED

    Source sequence(s)
    AC104446, AC112215
    UniProtKB/TrEMBL
    E7EVG2
    Conserved Domains (8) summary
    cd05515
    Location:646 → 750
    Bromo_polybromo_V; Bromodomain, polybromo repeat V. Polybromo is a nuclear protein of unknown function, which contains 6 bromodomains. The human ortholog BAF180 is part of a SWI/SNF chromatin-remodeling complex, and it may carry out the functions of Yeast Rsc-1 and Rsc-2. ...
    cd05518
    Location:507 → 610
    Bromo_polybromo_IV; Bromodomain, polybromo repeat IV. Polybromo is a nuclear protein of unknown function, which contains 6 bromodomains. The human ortholog BAF180 is part of a SWI/SNF chromatin-remodeling complex, and it may carry out the functions of Yeast Rsc-1 and Rsc-2. ...
    cd05520
    Location:371 → 472
    Bromo_polybromo_III; Bromodomain, polybromo repeat III. Polybromo is a nuclear protein of unknown function, which contains 6 bromodomains. The human ortholog BAF180 is part of a SWI/SNF chromatin-remodeling complex, and it may carry out the functions of Yeast Rsc-1 and Rsc-2. ...
    cd05524
    Location:65 → 177
    Bromo_polybromo_I; Bromodomain, polybromo repeat I. Polybromo is a nuclear protein of unknown function, which contains 6 bromodomains. The human ortholog BAF180 is part of a SWI/SNF chromatin-remodeling complex, and it may carry out the functions of Yeast Rsc-1 and Rsc-2. ...
    cd05526
    Location:763 → 870
    Bromo_polybromo_VI; Bromodomain, polybromo repeat VI. Polybromo is a nuclear protein of unknown function, which contains 6 bromodomains. The human ortholog BAF180 is part of a SWI/SNF chromatin-remodeling complex, and it may carry out the functions of Yeast Rsc-1 and Rsc-2. ...
    cd00084
    Location:1368 → 1417
    HMG-box; High Mobility Group (HMG)-box is found in a variety of eukaryotic chromosomal proteins and transcription factors. HMGs bind to the minor groove of DNA and have been classified by DNA binding preferences. Two phylogenically distinct groups of Class I ...
    cd04717
    Location:945 → 1062
    BAH_polybromo; BAH, or Bromo Adjacent Homology domain, as present in polybromo and yeast RSC1/2. The human polybromo protein (BAF180) is a component of the SWI/SNF chromatin-remodeling complex PBAF. It is thought that polybromo participates in transcriptional ...
    cl02556
    Location:203 → 287
    Bromodomain; Bromodomains are found in many chromatin-associated proteins and in nuclear histone acetyltransferases. They interact specifically with acetylated lysine.

  26. NM_001394879.1 → NP_001381808.1  protein polybromo-1 isoform 24

    Status: REVIEWED

    Source sequence(s)
    AC104446, AC112215
    UniProtKB/TrEMBL
    E7EVG2
    Conserved Domains (8) summary
    cd05515
    Location:626 → 730
    Bromo_polybromo_V; Bromodomain, polybromo repeat V. Polybromo is a nuclear protein of unknown function, which contains 6 bromodomains. The human ortholog BAF180 is part of a SWI/SNF chromatin-remodeling complex, and it may carry out the functions of Yeast Rsc-1 and Rsc-2. ...
    cd05517
    Location:182 → 284
    Bromo_polybromo_II; Bromodomain, polybromo repeat II. Polybromo is a nuclear protein of unknown function, which contains 6 bromodomains. The human ortholog BAF180 is part of a SWI/SNF chromatin-remodeling complex, and it may carry out the functions of Yeast Rsc-1 and Rsc-2. ...
    cd05518
    Location:487 → 590
    Bromo_polybromo_IV; Bromodomain, polybromo repeat IV. Polybromo is a nuclear protein of unknown function, which contains 6 bromodomains. The human ortholog BAF180 is part of a SWI/SNF chromatin-remodeling complex, and it may carry out the functions of Yeast Rsc-1 and Rsc-2. ...
    cd05520
    Location:351 → 452
    Bromo_polybromo_III; Bromodomain, polybromo repeat III. Polybromo is a nuclear protein of unknown function, which contains 6 bromodomains. The human ortholog BAF180 is part of a SWI/SNF chromatin-remodeling complex, and it may carry out the functions of Yeast Rsc-1 and Rsc-2. ...
    cd05524
    Location:44 → 156
    Bromo_polybromo_I; Bromodomain, polybromo repeat I. Polybromo is a nuclear protein of unknown function, which contains 6 bromodomains. The human ortholog BAF180 is part of a SWI/SNF chromatin-remodeling complex, and it may carry out the functions of Yeast Rsc-1 and Rsc-2. ...
    cd05526
    Location:743 → 850
    Bromo_polybromo_VI; Bromodomain, polybromo repeat VI. Polybromo is a nuclear protein of unknown function, which contains 6 bromodomains. The human ortholog BAF180 is part of a SWI/SNF chromatin-remodeling complex, and it may carry out the functions of Yeast Rsc-1 and Rsc-2. ...
    cd00084
    Location:1348 → 1412
    HMG-box; High Mobility Group (HMG)-box is found in a variety of eukaryotic chromosomal proteins and transcription factors. HMGs bind to the minor groove of DNA and have been classified by DNA binding preferences. Two phylogenically distinct groups of Class I ...
    cd04717
    Location:925 → 1042
    BAH_polybromo; BAH, or Bromo Adjacent Homology domain, as present in polybromo and yeast RSC1/2. The human polybromo protein (BAF180) is a component of the SWI/SNF chromatin-remodeling complex PBAF. It is thought that polybromo participates in transcriptional ...

  27. NM_001394880.1 → NP_001381809.1  protein polybromo-1 isoform 25

    Status: REVIEWED

    Source sequence(s)
    AC104446, AC112215
    Conserved Domains (2) summary
    cd05517
    Location:203 → 305
    Bromo_polybromo_II; Bromodomain, polybromo repeat II. Polybromo is a nuclear protein of unknown function, which contains 6 bromodomains. The human ortholog BAF180 is part of a SWI/SNF chromatin-remodeling complex, and it may carry out the functions of Yeast Rsc-1 and Rsc-2. ...
    cd05524
    Location:65 → 177
    Bromo_polybromo_I; Bromodomain, polybromo repeat I. Polybromo is a nuclear protein of unknown function, which contains 6 bromodomains. The human ortholog BAF180 is part of a SWI/SNF chromatin-remodeling complex, and it may carry out the functions of Yeast Rsc-1 and Rsc-2. ...

  28. NM_001394881.1 → NP_001381810.1  protein polybromo-1 isoform 26

    Status: REVIEWED

    Source sequence(s)
    AC104446, AC112215
    Conserved Domains (2) summary
    cd05517
    Location:182 → 284
    Bromo_polybromo_II; Bromodomain, polybromo repeat II. Polybromo is a nuclear protein of unknown function, which contains 6 bromodomains. The human ortholog BAF180 is part of a SWI/SNF chromatin-remodeling complex, and it may carry out the functions of Yeast Rsc-1 and Rsc-2. ...
    cd05524
    Location:44 → 156
    Bromo_polybromo_I; Bromodomain, polybromo repeat I. Polybromo is a nuclear protein of unknown function, which contains 6 bromodomains. The human ortholog BAF180 is part of a SWI/SNF chromatin-remodeling complex, and it may carry out the functions of Yeast Rsc-1 and Rsc-2. ...

  29. NM_001400470.1 → NP_001387399.1  protein polybromo-1 isoform 16

    Status: REVIEWED

    Source sequence(s)
    AC104446, AC112215
    Consensus CDS
    CCDS93286.1
    UniProtKB/Swiss-Prot
    A1L381, A1L382, A4FUJ7, Q1RMD1, Q1RMD2, Q86U86, Q96MS2, Q9H2T3, Q9H2T4, Q9H2T5, Q9H301, Q9H314

  30. NM_001400471.1 → NP_001387400.1  protein polybromo-1 isoform 27

    Status: REVIEWED

    Source sequence(s)
    AC104446, AC112215

  31. NM_001400472.1 → NP_001387401.1  protein polybromo-1 isoform 28

    Status: REVIEWED

    Source sequence(s)
    AC104446, AC112215

  32. NM_001400473.1 → NP_001387402.1  protein polybromo-1 isoform 29

    Status: REVIEWED

    Source sequence(s)
    AC104446, AC112215

  33. NM_001400474.1 → NP_001387403.1  protein polybromo-1 isoform 6

    Status: REVIEWED

    Source sequence(s)
    AC104446, AC112215
    Consensus CDS
    CCDS87087.1

  34. NM_001400475.1 → NP_001387404.1  protein polybromo-1 isoform 6

    Status: REVIEWED

    Source sequence(s)
    AC104446, AC112215
    Consensus CDS
    CCDS87087.1

  35. NM_001400479.1 → NP_001387408.1  protein polybromo-1 isoform 6

    Status: REVIEWED

    Source sequence(s)
    AC104446, AC112215
    Consensus CDS
    CCDS87087.1

  36. NM_001400481.1 → NP_001387410.1  protein polybromo-1 isoform 20

    Status: REVIEWED

    Source sequence(s)
    AC104446, AC112215

  37. NM_001400484.1 → NP_001387413.1  protein polybromo-1 isoform 21

    Status: REVIEWED

    Source sequence(s)
    AC104446, AC112215
    Consensus CDS
    CCDS93285.1

  38. NM_001400487.1 → NP_001387416.1  protein polybromo-1 isoform 30

    Status: REVIEWED

    Source sequence(s)
    AC104446, AC112215
    Consensus CDS
    CCDS2859.1

  39. NM_001400490.1 → NP_001387419.1  protein polybromo-1 isoform 31

    Status: REVIEWED

    Source sequence(s)
    AC104446, AC112215

  40. NM_001400496.1 → NP_001387425.1  protein polybromo-1 isoform 4

    Status: REVIEWED

    Source sequence(s)
    AC104446, AC112215
    Consensus CDS
    CCDS2860.1

  41. NM_001400500.1 → NP_001387429.1  protein polybromo-1 isoform 4

    Status: REVIEWED

    Source sequence(s)
    AC104446, AC112215
    Consensus CDS
    CCDS2860.1

  42. NM_001400501.1 → NP_001387430.1  protein polybromo-1 isoform 4

    Status: REVIEWED

    Source sequence(s)
    AC104446, AC112215
    Consensus CDS
    CCDS2860.1

  43. NM_001400504.1 → NP_001387433.1  protein polybromo-1 isoform 31

    Status: REVIEWED

    Source sequence(s)
    AC104446, AC112215

  44. NM_001405552.1 → NP_001392481.1  protein polybromo-1 isoform 52

    Status: REVIEWED

    Source sequence(s)
    AC104446, AC112215

  45. NM_001405553.1 → NP_001392482.1  protein polybromo-1 isoform 55

    Status: REVIEWED

    Source sequence(s)
    AC104446, AC112215

  46. NM_001405554.1 → NP_001392483.1  protein polybromo-1 isoform 53

    Status: REVIEWED

    Source sequence(s)
    AC104446, AC112215

  47. NM_001405555.1 → NP_001392484.1  protein polybromo-1 isoform 4

    Status: REVIEWED

    Source sequence(s)
    AC104446, AC112215
    Related
    ENSP00000338302.4, ENST00000337303.8

  48. NM_001405556.1 → NP_001392485.1  protein polybromo-1 isoform 6

    Status: REVIEWED

    Source sequence(s)
    AC104446, AC112215
    Related
    ENSP00000386593.1, ENST00000409057.5

  49. NM_001405557.1 → NP_001392486.1  protein polybromo-1 isoform 6

    Status: REVIEWED

    Source sequence(s)
    AC104446, AC112215

  50. NM_001405558.1 → NP_001392487.1  protein polybromo-1 isoform 21

    Status: REVIEWED

    Source sequence(s)
    AC104446, AC112215

  51. NM_001405559.1 → NP_001392488.1  protein polybromo-1 isoform 54

    Status: REVIEWED

    Source sequence(s)
    AC104446, AC112215

  52. NM_001405560.1 → NP_001392489.1  protein polybromo-1 isoform 71

    Status: REVIEWED

    Source sequence(s)
    AC104446, AC112215

  53. NM_001405561.1 → NP_001392490.1  protein polybromo-1 isoform 20

    Status: REVIEWED

    Source sequence(s)
    AC104446, AC112215

  54. NM_001405563.1 → NP_001392492.1  protein polybromo-1 isoform 22

    Status: REVIEWED

    Source sequence(s)
    AC104446, AC112215

  55. NM_001405564.1 → NP_001392493.1  protein polybromo-1 isoform 64

    Status: REVIEWED

    Source sequence(s)
    AC104446, AC112215

  56. NM_001405565.1 → NP_001392494.1  protein polybromo-1 isoform 21

    Status: REVIEWED

    Source sequence(s)
    AC104446, AC112215
    Related
    ENSP00000386529.1, ENST00000410007.5

  57. NM_001405566.1 → NP_001392495.1  protein polybromo-1 isoform 78

    Status: REVIEWED

    Source sequence(s)
    AC104446, AC112215

  58. NM_001405567.1 → NP_001392496.1  protein polybromo-1 isoform 51

    Status: REVIEWED

    Source sequence(s)
    AC104446, AC112215

  59. NM_001405568.1 → NP_001392497.1  protein polybromo-1 isoform 58

    Status: REVIEWED

    Source sequence(s)
    AC104446, AC112215

  60. NM_001405569.1 → NP_001392498.1  protein polybromo-1 isoform 59

    Status: REVIEWED

    Source sequence(s)
    AC104446, AC112215

  61. NM_001405570.1 → NP_001392499.1  protein polybromo-1 isoform 50

    Status: REVIEWED

    Source sequence(s)
    AC104446, AC112215

  62. NM_001405571.1 → NP_001392500.1  protein polybromo-1 isoform 57

    Status: REVIEWED

    Source sequence(s)
    AC104446, AC112215

  63. NM_001405572.1 → NP_001392501.1  protein polybromo-1 isoform 67

    Status: REVIEWED

    Source sequence(s)
    AC104446, AC112215

  64. NM_001405573.1 → NP_001392502.1  protein polybromo-1 isoform 68

    Status: REVIEWED

    Source sequence(s)
    AC104446, AC112215

  65. NM_001405574.1 → NP_001392503.1  protein polybromo-1 isoform 56

    Status: REVIEWED

    Source sequence(s)
    AC104446, AC112215

  66. NM_001405575.1 → NP_001392504.1  protein polybromo-1 isoform 20

    Status: REVIEWED

    Source sequence(s)
    AC104446, AC112215

  67. NM_001405576.1 → NP_001392505.1  protein polybromo-1 isoform 70

    Status: REVIEWED

    Source sequence(s)
    AC104446, AC112215

  68. NM_001405577.1 → NP_001392506.1  protein polybromo-1 isoform 4

    Status: REVIEWED

    Source sequence(s)
    AC104446, AC112215

  69. NM_001405578.1 → NP_001392507.1  protein polybromo-1 isoform 20

    Status: REVIEWED

    Source sequence(s)
    AC104446, AC112215

  70. NM_001405579.1 → NP_001392508.1  protein polybromo-1 isoform 29

    Status: REVIEWED

    Source sequence(s)
    AC104446, AC112215

  71. NM_001405580.1 → NP_001392509.1  protein polybromo-1 isoform 69

    Status: REVIEWED

    Source sequence(s)
    AC104446, AC112215

  72. NM_001405581.1 → NP_001392510.1  protein polybromo-1 isoform 16

    Status: REVIEWED

    Source sequence(s)
    AC104446, AC112215
    UniProtKB/Swiss-Prot
    A1L381, A1L382, A4FUJ7, Q1RMD1, Q1RMD2, Q86U86, Q96MS2, Q9H2T3, Q9H2T4, Q9H2T5, Q9H301, Q9H314
    Related
    ENSP00000296302.7, ENST00000296302.11

  73. NM_001405582.1 → NP_001392511.1  protein polybromo-1 isoform 30

    Status: REVIEWED

    Source sequence(s)
    AC104446, AC112215
    Related
    ENSP00000349213.4, ENST00000356770.8

  74. NM_001405583.1 → NP_001392512.1  protein polybromo-1 isoform 18

    Status: REVIEWED

    Source sequence(s)
    AC104446, AC112215

  75. NM_001405584.1 → NP_001392513.1  protein polybromo-1 isoform 18

    Status: REVIEWED

    Source sequence(s)
    AC104446, AC112215
    Related
    ENSP00000386643.3, ENST00000409114.7

  76. NM_001405585.1 → NP_001392514.1  protein polybromo-1 isoform 20

    Status: REVIEWED

    Source sequence(s)
    AC104446, AC112215

  77. NM_001405586.1 → NP_001392515.1  protein polybromo-1 isoform 83

    Status: REVIEWED

    Source sequence(s)
    AC104446, AC112215

  78. NM_001405587.1 → NP_001392516.1  protein polybromo-1 isoform 65

    Status: REVIEWED

    Source sequence(s)
    AC104446, AC112215

  79. NM_001405588.1 → NP_001392517.1  protein polybromo-1 isoform 54

    Status: REVIEWED

    Source sequence(s)
    AC104446, AC112215

  80. NM_001405589.1 → NP_001392518.1  protein polybromo-1 isoform 51

    Status: REVIEWED

    Source sequence(s)
    AC104446, AC112215

  81. NM_001405590.1 → NP_001392519.1  protein polybromo-1 isoform 20

    Status: REVIEWED

    Source sequence(s)
    AC104446, AC112215

  82. NM_001405591.1 → NP_001392520.1  protein polybromo-1 isoform 61

    Status: REVIEWED

    Source sequence(s)
    AC104446, AC112215

  83. NM_001405592.1 → NP_001392521.1  protein polybromo-1 isoform 31

    Status: REVIEWED

    Source sequence(s)
    AC104446, AC112215

  84. NM_001405593.1 → NP_001392522.1  protein polybromo-1 isoform 4

    Status: REVIEWED

    Source sequence(s)
    AC104446, AC112215

  85. NM_001405594.1 → NP_001392523.1  protein polybromo-1 isoform 16

    Status: REVIEWED

    Source sequence(s)
    AC104446, AC112215
    UniProtKB/Swiss-Prot
    A1L381, A1L382, A4FUJ7, Q1RMD1, Q1RMD2, Q86U86, Q96MS2, Q9H2T3, Q9H2T4, Q9H2T5, Q9H301, Q9H314

  86. NM_001405595.1 → NP_001392524.1  protein polybromo-1 isoform 62

    Status: REVIEWED

    Source sequence(s)
    AC104446, AC112215

  87. NM_001405596.1 → NP_001392525.1  protein polybromo-1 isoform 77

    Status: REVIEWED

    Source sequence(s)
    AC104446, AC112215

  88. NM_001405597.1 → NP_001392526.1  protein polybromo-1 isoform 63

    Status: REVIEWED

    Source sequence(s)
    AC104446, AC112215

  89. NM_001405598.1 → NP_001392527.1  protein polybromo-1 isoform 49

    Status: REVIEWED

    Source sequence(s)
    AC104446, AC112215

  90. NM_001405599.1 → NP_001392528.1  protein polybromo-1 isoform 30

    Status: REVIEWED

    Source sequence(s)
    AC104446, AC112215

  91. NM_001405600.1 → NP_001392529.1  protein polybromo-1 isoform 17

    Status: REVIEWED

    Source sequence(s)
    AC104446, AC112215

  92. NM_001405601.1 → NP_001392530.1  protein polybromo-1 isoform 48

    Status: REVIEWED

    Source sequence(s)
    AC104446, AC112215
    UniProtKB/TrEMBL
    A0A9L9PXL4

  93. NM_001405602.1 → NP_001392531.1  protein polybromo-1 isoform 84

    Status: REVIEWED

    Source sequence(s)
    AC104446, AC112215

  94. NM_001405603.1 → NP_001392532.1  protein polybromo-1 isoform 16

    Status: REVIEWED

    Source sequence(s)
    AC104446, AC112215
    UniProtKB/Swiss-Prot
    A1L381, A1L382, A4FUJ7, Q1RMD1, Q1RMD2, Q86U86, Q96MS2, Q9H2T3, Q9H2T4, Q9H2T5, Q9H301, Q9H314

  95. NM_001405604.1 → NP_001392533.1  protein polybromo-1 isoform 82

    Status: REVIEWED

    Source sequence(s)
    AC104446, AC112215

  96. NM_001405605.1 → NP_001392534.1  protein polybromo-1 isoform 31

    Status: REVIEWED

    Source sequence(s)
    AC104446, AC112215

  97. NM_001405606.1 → NP_001392535.1  protein polybromo-1 isoform 30

    Status: REVIEWED

    Source sequence(s)
    AC104446, AC112215

  98. NM_001405607.1 → NP_001392536.1  protein polybromo-1 isoform 48

    Status: REVIEWED

    Source sequence(s)
    AC104446, AC112215
    UniProtKB/TrEMBL
    A0A9L9PXL4
    Related
    ENSP00000516722.1, ENST00000707071.1

  99. NM_001405608.1 → NP_001392537.1  protein polybromo-1 isoform 74

    Status: REVIEWED

    Source sequence(s)
    AC104446, AC112215

  100. NM_001405609.1 → NP_001392538.1  protein polybromo-1 isoform 66

    Status: REVIEWED

    Source sequence(s)
    AC104446, AC112215

  101. NM_001405610.1 → NP_001392539.1  protein polybromo-1 isoform 72

    Status: REVIEWED

    Source sequence(s)
    AC104446, AC112215
    Related
    ENSP00000387775.1, ENST00000423351.5

  102. NM_001405611.1 → NP_001392540.1  protein polybromo-1 isoform 73

    Status: REVIEWED

    Source sequence(s)
    AC104446, AC112215

  103. NM_001405612.1 → NP_001392541.1  protein polybromo-1 isoform 76

    Status: REVIEWED

    Source sequence(s)
    AC104446, AC112215
    Related
    ENSP00000397662.1, ENST00000446103.5

  104. NM_001405613.1 → NP_001392542.1  protein polybromo-1 isoform 80

    Status: REVIEWED

    Source sequence(s)
    AC104446, AC112215

  105. NM_001405614.1 → NP_001392543.1  protein polybromo-1 isoform 26

    Status: REVIEWED

    Source sequence(s)
    AC104446, AC112215

  106. NM_001405615.1 → NP_001392544.1  protein polybromo-1 isoform 26

    Status: REVIEWED

    Source sequence(s)
    AC104446, AC112215

  107. NM_001405616.1 → NP_001392545.1  protein polybromo-1 isoform 26

    Status: REVIEWED

    Source sequence(s)
    AC104446, AC112215

  108. NM_001405617.1 → NP_001392546.1  protein polybromo-1 isoform 81

    Status: REVIEWED

    Source sequence(s)
    AC104446, AC112215

  109. NM_001405618.1 → NP_001392547.1  protein polybromo-1 isoform 81

    Status: REVIEWED

    Source sequence(s)
    AC104446, AC112215

  110. NM_001405619.1 → NP_001392548.1  protein polybromo-1 isoform 79

    Status: REVIEWED

    Source sequence(s)
    AC104446, AC112215

  111. NM_001405620.1 → NP_001392549.1  protein polybromo-1 isoform 81

    Status: REVIEWED

    Source sequence(s)
    AC104446, AC112215

  112. NM_001405621.1 → NP_001392550.1  protein polybromo-1 isoform 79

    Status: REVIEWED

    Source sequence(s)
    AC104446, AC112215

  113. NM_001405622.1 → NP_001392551.1  protein polybromo-1 isoform 55

    Status: REVIEWED

    Source sequence(s)
    AC104446, AC112215

  114. NM_001405623.1 → NP_001392552.1  protein polybromo-1 isoform 6

    Status: REVIEWED

    Source sequence(s)
    AC104446, AC112215

  115. NM_001405624.1 → NP_001392553.1  protein polybromo-1 isoform 22

    Status: REVIEWED

    Source sequence(s)
    AC104446, AC112215

  116. NM_001405625.1 → NP_001392554.1  protein polybromo-1 isoform 75

    Status: REVIEWED

    Source sequence(s)
    AC104446, AC112215

  117. NM_001405626.1 → NP_001392555.1  protein polybromo-1 isoform 4

    Status: REVIEWED

    Source sequence(s)
    AC104446, AC112215

  118. NM_001405627.1 → NP_001392556.1  protein polybromo-1 isoform 4

    Status: REVIEWED

    Source sequence(s)
    AC104446, AC112215

  119. NM_001405628.1 → NP_001392557.1  protein polybromo-1 isoform 6

    Status: REVIEWED

    Source sequence(s)
    AC104446, AC112215

  120. NM_001405629.1 → NP_001392558.1  protein polybromo-1 isoform 51

    Status: REVIEWED

    Source sequence(s)
    AC104446, AC112215

  121. NM_001405630.1 → NP_001392559.1  protein polybromo-1 isoform 6

    Status: REVIEWED

    Source sequence(s)
    AC104446, AC112215

  122. NM_001405631.1 → NP_001392560.1  protein polybromo-1 isoform 6

    Status: REVIEWED

    Source sequence(s)
    AC104446, AC112215

  123. NM_001405632.1 → NP_001392561.1  protein polybromo-1 isoform 20

    Status: REVIEWED

    Source sequence(s)
    AC104446, AC112215

  124. NM_001405633.1 → NP_001392562.1  protein polybromo-1 isoform 21

    Status: REVIEWED

    Source sequence(s)
    AC104446, AC112215

  125. NM_001405634.1 → NP_001392563.1  protein polybromo-1 isoform 31

    Status: REVIEWED

    Source sequence(s)
    AC104446, AC112215

  126. NM_001405635.1 → NP_001392564.1  protein polybromo-1 isoform 21

    Status: REVIEWED

    Source sequence(s)
    AC104446, AC112215

  127. NM_001405636.1 → NP_001392565.1  protein polybromo-1 isoform 64

    Status: REVIEWED

    Source sequence(s)
    AC104446, AC112215

  128. NM_001405637.1 → NP_001392566.1  protein polybromo-1 isoform 60

    Status: REVIEWED

    Source sequence(s)
    AC104446, AC112215

  129. NM_001405638.1 → NP_001392567.1  protein polybromo-1 isoform 30

    Status: REVIEWED

    Source sequence(s)
    AC104446, AC112215

  130. NM_001405639.1 → NP_001392568.1  protein polybromo-1 isoform 54

    Status: REVIEWED

    Source sequence(s)
    AC104446, AC112215

  131. NM_001405640.1 → NP_001392569.1  protein polybromo-1 isoform 4

    Status: REVIEWED

    Source sequence(s)
    AC104446, AC112215

  132. NM_001405641.1 → NP_001392570.1  protein polybromo-1 isoform 18

    Status: REVIEWED

    Source sequence(s)
    AC104446, AC112215

  133. NM_001405642.1 → NP_001392571.1  protein polybromo-1 isoform 71

    Status: REVIEWED

    Source sequence(s)
    AC104446, AC112215

  134. NM_001405643.1 → NP_001392572.1  protein polybromo-1 isoform 18

    Status: REVIEWED

    Source sequence(s)
    AC104446, AC112215

  135. NM_018313.5 → NP_060783.3  protein polybromo-1 isoform 2

    See identical proteins and their annotated locations for NP_060783.3

    Status: REVIEWED

    Description
    Transcript Variant: This variant (2) contains multiple differences in the coding region, compared to variant 5. It encodes isoform 2, which is shorter than isoform 5. Variants 2 and 4 encode isoforms that are of the same length, but have distinct protein sequences.
    Source sequence(s)
    AC104446, AF177387, AF197569, BE672944, BG778619, BU171600, BU619411, CA438315, CV573455, DA039085
    Consensus CDS
    CCDS43099.1
    UniProtKB/TrEMBL
    E7EVG2
    Related
    ENSP00000378307.3, ENST00000394830.7
    Conserved Domains (9) summary
    cd05515
    Location:658 → 762
    Bromo_polybromo_V; Bromodomain, polybromo repeat V. Polybromo is a nuclear protein of unknown function, which contains 6 bromodomains. The human ortholog BAF180 is part of a SWI/SNF chromatin-remodeling complex, and it may carry out the functions of Yeast Rsc-1 and Rsc-2. ...
    cd05517
    Location:182 → 284
    Bromo_polybromo_II; Bromodomain, polybromo repeat II. Polybromo is a nuclear protein of unknown function, which contains 6 bromodomains. The human ortholog BAF180 is part of a SWI/SNF chromatin-remodeling complex, and it may carry out the functions of Yeast Rsc-1 and Rsc-2. ...
    cd05518
    Location:519 → 622
    Bromo_polybromo_IV; Bromodomain, polybromo repeat IV. Polybromo is a nuclear protein of unknown function, which contains 6 bromodomains. The human ortholog BAF180 is part of a SWI/SNF chromatin-remodeling complex, and it may carry out the functions of Yeast Rsc-1 and Rsc-2. ...
    cd05520
    Location:383 → 484
    Bromo_polybromo_III; Bromodomain, polybromo repeat III. Polybromo is a nuclear protein of unknown function, which contains 6 bromodomains. The human ortholog BAF180 is part of a SWI/SNF chromatin-remodeling complex, and it may carry out the functions of Yeast Rsc-1 and Rsc-2. ...
    cd05524
    Location:44 → 156
    Bromo_polybromo_I; Bromodomain, polybromo repeat I. Polybromo is a nuclear protein of unknown function, which contains 6 bromodomains. The human ortholog BAF180 is part of a SWI/SNF chromatin-remodeling complex, and it may carry out the functions of Yeast Rsc-1 and Rsc-2. ...
    cd05526
    Location:775 → 882
    Bromo_polybromo_VI; Bromodomain, polybromo repeat VI. Polybromo is a nuclear protein of unknown function, which contains 6 bromodomains. The human ortholog BAF180 is part of a SWI/SNF chromatin-remodeling complex, and it may carry out the functions of Yeast Rsc-1 and Rsc-2. ...
    cd00084
    Location:1328 → 1377
    HMG-box; High Mobility Group (HMG)-box is found in a variety of eukaryotic chromosomal proteins and transcription factors. HMGs bind to the minor groove of DNA and have been classified by DNA binding preferences. Two phylogenically distinct groups of Class I ...
    cd04717
    Location:1130 → 1248
    BAH_polybromo; BAH, or Bromo Adjacent Homology domain, as present in polybromo and yeast RSC1/2. The human polybromo protein (BAF180) is a component of the SWI/SNF chromatin-remodeling complex PBAF. It is thought that polybromo participates in transcriptional ...
    cl02608
    Location:957 → 1049
    BAH; BAH, or Bromo Adjacent Homology domain (also called ELM1 and BAM for Bromo Adjacent Motif). BAH domains have first been described as domains found in the polybromo protein and Yeast Rsc1/Rsc2 (Remodeling of the Structure of Chromatin). They also occur in ...

  136. NM_181042.5 → NP_851385.1  protein polybromo-1 isoform 4

    Status: REVIEWED

    Description
    Transcript Variant: This variant (4) This variant (2) differs in the 5' UTR and contains multiple differences in the coding region, compared to variant 5. It encodes isoform 4, which is shorter than isoform 5. Variants 2 and 4 encode isoforms that are the same length, but have distinct protein sequences.
    Source sequence(s)
    AC104446, AC112215
    Consensus CDS
    CCDS2860.1
    UniProtKB/TrEMBL
    E7EVG2
    Conserved Domains (8) summary
    cd05515
    Location:658 → 762
    Bromo_polybromo_V; Bromodomain, polybromo repeat V. Polybromo is a nuclear protein of unknown function, which contains 6 bromodomains. The human ortholog BAF180 is part of a SWI/SNF chromatin-remodeling complex, and it may carry out the functions of Yeast Rsc-1 and Rsc-2. ...
    cd05517
    Location:182 → 284
    Bromo_polybromo_II; Bromodomain, polybromo repeat II. Polybromo is a nuclear protein of unknown function, which contains 6 bromodomains. The human ortholog BAF180 is part of a SWI/SNF chromatin-remodeling complex, and it may carry out the functions of Yeast Rsc-1 and Rsc-2. ...
    cd05518
    Location:519 → 622
    Bromo_polybromo_IV; Bromodomain, polybromo repeat IV. Polybromo is a nuclear protein of unknown function, which contains 6 bromodomains. The human ortholog BAF180 is part of a SWI/SNF chromatin-remodeling complex, and it may carry out the functions of Yeast Rsc-1 and Rsc-2. ...
    cd05520
    Location:383 → 484
    Bromo_polybromo_III; Bromodomain, polybromo repeat III. Polybromo is a nuclear protein of unknown function, which contains 6 bromodomains. The human ortholog BAF180 is part of a SWI/SNF chromatin-remodeling complex, and it may carry out the functions of Yeast Rsc-1 and Rsc-2. ...
    cd05524
    Location:44 → 156
    Bromo_polybromo_I; Bromodomain, polybromo repeat I. Polybromo is a nuclear protein of unknown function, which contains 6 bromodomains. The human ortholog BAF180 is part of a SWI/SNF chromatin-remodeling complex, and it may carry out the functions of Yeast Rsc-1 and Rsc-2. ...
    cd05526
    Location:775 → 882
    Bromo_polybromo_VI; Bromodomain, polybromo repeat VI. Polybromo is a nuclear protein of unknown function, which contains 6 bromodomains. The human ortholog BAF180 is part of a SWI/SNF chromatin-remodeling complex, and it may carry out the functions of Yeast Rsc-1 and Rsc-2. ...
    cd00084
    Location:1380 → 1429
    HMG-box; High Mobility Group (HMG)-box is found in a variety of eukaryotic chromosomal proteins and transcription factors. HMGs bind to the minor groove of DNA and have been classified by DNA binding preferences. Two phylogenically distinct groups of Class I ...
    cd04717
    Location:957 → 1074
    BAH_polybromo; BAH, or Bromo Adjacent Homology domain, as present in polybromo and yeast RSC1/2. The human polybromo protein (BAF180) is a component of the SWI/SNF chromatin-remodeling complex PBAF. It is thought that polybromo participates in transcriptional ...

RNA

  1. NR_174502.1 RNA Sequence

    Status: REVIEWED

    Source sequence(s)
    AC104446, AC112215

  2. NR_175959.1 RNA Sequence

    Status: REVIEWED

    Source sequence(s)
    AC104446, AC112215

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000003.12 Reference GRCh38.p14 Primary Assembly

    Range
    52545367..52685913 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_047448460.1 → XP_047304416.1  protein polybromo-1 isoform X19

  2. XM_047448462.1 → XP_047304418.1  protein polybromo-1 isoform X20

  3. XM_047448449.1 → XP_047304405.1  protein polybromo-1 isoform X9

  4. XM_017006734.3 → XP_016862223.1  protein polybromo-1 isoform X8

    UniProtKB/TrEMBL
    E7EVG2

  5. XM_047448445.1 → XP_047304401.1  protein polybromo-1 isoform X4

  6. XM_017006744.2 → XP_016862233.1  protein polybromo-1 isoform X13

    UniProtKB/TrEMBL
    E7EVG2

  7. XM_024453619.2 → XP_024309387.1  protein polybromo-1 isoform X7

    UniProtKB/TrEMBL
    E7EVG2
    Conserved Domains (8) summary
    cd05515
    Location:691 → 795
    Bromo_polybromo_V; Bromodomain, polybromo repeat V. Polybromo is a nuclear protein of unknown function, which contains 6 bromodomains. The human ortholog BAF180 is part of a SWI/SNF chromatin-remodeling complex, and it may carry out the functions of Yeast Rsc-1 and Rsc-2. ...
    cd05517
    Location:200 → 302
    Bromo_polybromo_II; Bromodomain, polybromo repeat II. Polybromo is a nuclear protein of unknown function, which contains 6 bromodomains. The human ortholog BAF180 is part of a SWI/SNF chromatin-remodeling complex, and it may carry out the functions of Yeast Rsc-1 and Rsc-2. ...
    cd05518
    Location:552 → 655
    Bromo_polybromo_IV; Bromodomain, polybromo repeat IV. Polybromo is a nuclear protein of unknown function, which contains 6 bromodomains. The human ortholog BAF180 is part of a SWI/SNF chromatin-remodeling complex, and it may carry out the functions of Yeast Rsc-1 and Rsc-2. ...
    cd05520
    Location:401 → 502
    Bromo_polybromo_III; Bromodomain, polybromo repeat III. Polybromo is a nuclear protein of unknown function, which contains 6 bromodomains. The human ortholog BAF180 is part of a SWI/SNF chromatin-remodeling complex, and it may carry out the functions of Yeast Rsc-1 and Rsc-2. ...
    cd05524
    Location:62 → 174
    Bromo_polybromo_I; Bromodomain, polybromo repeat I. Polybromo is a nuclear protein of unknown function, which contains 6 bromodomains. The human ortholog BAF180 is part of a SWI/SNF chromatin-remodeling complex, and it may carry out the functions of Yeast Rsc-1 and Rsc-2. ...
    cd05526
    Location:808 → 915
    Bromo_polybromo_VI; Bromodomain, polybromo repeat VI. Polybromo is a nuclear protein of unknown function, which contains 6 bromodomains. The human ortholog BAF180 is part of a SWI/SNF chromatin-remodeling complex, and it may carry out the functions of Yeast Rsc-1 and Rsc-2. ...
    cd00084
    Location:1413 → 1477
    HMG-box; High Mobility Group (HMG)-box is found in a variety of eukaryotic chromosomal proteins and transcription factors. HMGs bind to the minor groove of DNA and have been classified by DNA binding preferences. Two phylogenically distinct groups of Class I ...
    cd04717
    Location:990 → 1107
    BAH_polybromo; BAH, or Bromo Adjacent Homology domain, as present in polybromo and yeast RSC1/2. The human polybromo protein (BAF180) is a component of the SWI/SNF chromatin-remodeling complex PBAF. It is thought that polybromo participates in transcriptional ...

  8. XM_047448457.1 → XP_047304413.1  protein polybromo-1 isoform X17

  9. XM_017006741.3 → XP_016862230.1  protein polybromo-1 isoform X10

    UniProtKB/TrEMBL
    E7EVG2
    Conserved Domains (8) summary
    cd05515
    Location:679 → 783
    Bromo_polybromo_V; Bromodomain, polybromo repeat V. Polybromo is a nuclear protein of unknown function, which contains 6 bromodomains. The human ortholog BAF180 is part of a SWI/SNF chromatin-remodeling complex, and it may carry out the functions of Yeast Rsc-1 and Rsc-2. ...
    cd05517
    Location:203 → 305
    Bromo_polybromo_II; Bromodomain, polybromo repeat II. Polybromo is a nuclear protein of unknown function, which contains 6 bromodomains. The human ortholog BAF180 is part of a SWI/SNF chromatin-remodeling complex, and it may carry out the functions of Yeast Rsc-1 and Rsc-2. ...
    cd05518
    Location:540 → 643
    Bromo_polybromo_IV; Bromodomain, polybromo repeat IV. Polybromo is a nuclear protein of unknown function, which contains 6 bromodomains. The human ortholog BAF180 is part of a SWI/SNF chromatin-remodeling complex, and it may carry out the functions of Yeast Rsc-1 and Rsc-2. ...
    cd05520
    Location:404 → 505
    Bromo_polybromo_III; Bromodomain, polybromo repeat III. Polybromo is a nuclear protein of unknown function, which contains 6 bromodomains. The human ortholog BAF180 is part of a SWI/SNF chromatin-remodeling complex, and it may carry out the functions of Yeast Rsc-1 and Rsc-2. ...
    cd05524
    Location:65 → 177
    Bromo_polybromo_I; Bromodomain, polybromo repeat I. Polybromo is a nuclear protein of unknown function, which contains 6 bromodomains. The human ortholog BAF180 is part of a SWI/SNF chromatin-remodeling complex, and it may carry out the functions of Yeast Rsc-1 and Rsc-2. ...
    cd05526
    Location:796 → 903
    Bromo_polybromo_VI; Bromodomain, polybromo repeat VI. Polybromo is a nuclear protein of unknown function, which contains 6 bromodomains. The human ortholog BAF180 is part of a SWI/SNF chromatin-remodeling complex, and it may carry out the functions of Yeast Rsc-1 and Rsc-2. ...
    cd00084
    Location:1401 → 1465
    HMG-box; High Mobility Group (HMG)-box is found in a variety of eukaryotic chromosomal proteins and transcription factors. HMGs bind to the minor groove of DNA and have been classified by DNA binding preferences. Two phylogenically distinct groups of Class I ...
    cd04717
    Location:978 → 1095
    BAH_polybromo; BAH, or Bromo Adjacent Homology domain, as present in polybromo and yeast RSC1/2. The human polybromo protein (BAF180) is a component of the SWI/SNF chromatin-remodeling complex PBAF. It is thought that polybromo participates in transcriptional ...

  10. XM_011533902.4 → XP_011532204.1  protein polybromo-1 isoform X5

    See identical proteins and their annotated locations for XP_011532204.1

    UniProtKB/TrEMBL
    E7EVG2
    Conserved Domains (8) summary
    cd05515
    Location:694 → 798
    Bromo_polybromo_V; Bromodomain, polybromo repeat V. Polybromo is a nuclear protein of unknown function, which contains 6 bromodomains. The human ortholog BAF180 is part of a SWI/SNF chromatin-remodeling complex, and it may carry out the functions of Yeast Rsc-1 and Rsc-2. ...
    cd05517
    Location:203 → 305
    Bromo_polybromo_II; Bromodomain, polybromo repeat II. Polybromo is a nuclear protein of unknown function, which contains 6 bromodomains. The human ortholog BAF180 is part of a SWI/SNF chromatin-remodeling complex, and it may carry out the functions of Yeast Rsc-1 and Rsc-2. ...
    cd05518
    Location:555 → 658
    Bromo_polybromo_IV; Bromodomain, polybromo repeat IV. Polybromo is a nuclear protein of unknown function, which contains 6 bromodomains. The human ortholog BAF180 is part of a SWI/SNF chromatin-remodeling complex, and it may carry out the functions of Yeast Rsc-1 and Rsc-2. ...
    cd05520
    Location:404 → 505
    Bromo_polybromo_III; Bromodomain, polybromo repeat III. Polybromo is a nuclear protein of unknown function, which contains 6 bromodomains. The human ortholog BAF180 is part of a SWI/SNF chromatin-remodeling complex, and it may carry out the functions of Yeast Rsc-1 and Rsc-2. ...
    cd05524
    Location:65 → 177
    Bromo_polybromo_I; Bromodomain, polybromo repeat I. Polybromo is a nuclear protein of unknown function, which contains 6 bromodomains. The human ortholog BAF180 is part of a SWI/SNF chromatin-remodeling complex, and it may carry out the functions of Yeast Rsc-1 and Rsc-2. ...
    cd05526
    Location:811 → 918
    Bromo_polybromo_VI; Bromodomain, polybromo repeat VI. Polybromo is a nuclear protein of unknown function, which contains 6 bromodomains. The human ortholog BAF180 is part of a SWI/SNF chromatin-remodeling complex, and it may carry out the functions of Yeast Rsc-1 and Rsc-2. ...
    cd00084
    Location:1416 → 1480
    HMG-box; High Mobility Group (HMG)-box is found in a variety of eukaryotic chromosomal proteins and transcription factors. HMGs bind to the minor groove of DNA and have been classified by DNA binding preferences. Two phylogenically distinct groups of Class I ...
    cd04717
    Location:993 → 1110
    BAH_polybromo; BAH, or Bromo Adjacent Homology domain, as present in polybromo and yeast RSC1/2. The human polybromo protein (BAF180) is a component of the SWI/SNF chromatin-remodeling complex PBAF. It is thought that polybromo participates in transcriptional ...

  11. XM_017006725.2 → XP_016862214.1  protein polybromo-1 isoform X1

    UniProtKB/TrEMBL
    E7EVG2

  12. XM_047448455.1 → XP_047304411.1  protein polybromo-1 isoform X15

  13. XM_017006730.2 → XP_016862219.1  protein polybromo-1 isoform X3

    UniProtKB/TrEMBL
    E7EVG2

  14. XM_047448447.1 → XP_047304403.1  protein polybromo-1 isoform X5

  15. XM_017006727.2 → XP_016862216.1  protein polybromo-1 isoform X1

    UniProtKB/TrEMBL
    E7EVG2

  16. XM_047448444.1 → XP_047304400.1  protein polybromo-1 isoform X4

  17. XM_047448448.1 → XP_047304404.1  protein polybromo-1 isoform X6

  18. XM_047448456.1 → XP_047304412.1  protein polybromo-1 isoform X16

  19. XM_047448446.1 → XP_047304402.1  protein polybromo-1 isoform X5

  20. XM_047448451.1 → XP_047304407.1  protein polybromo-1 isoform X12

  21. XM_047448443.1 → XP_047304399.1  protein polybromo-1 isoform X2

  22. XM_047448450.1 → XP_047304406.1  protein polybromo-1 isoform X11

  23. XM_047448442.1 → XP_047304398.1  protein polybromo-1 isoform X1

  24. XM_047448459.1 → XP_047304415.1  protein polybromo-1 isoform X18

  25. XM_047448453.1 → XP_047304409.1  protein polybromo-1 isoform X14

  26. XM_047448452.1 → XP_047304408.1  protein polybromo-1 isoform X13

  27. XM_017006731.2 → XP_016862220.1  protein polybromo-1 isoform X3

    UniProtKB/TrEMBL
    E7EVG2

  28. XM_017006742.2 → XP_016862231.1  protein polybromo-1 isoform X10

    UniProtKB/TrEMBL
    E7EVG2
    Conserved Domains (8) summary
    cd05515
    Location:679 → 783
    Bromo_polybromo_V; Bromodomain, polybromo repeat V. Polybromo is a nuclear protein of unknown function, which contains 6 bromodomains. The human ortholog BAF180 is part of a SWI/SNF chromatin-remodeling complex, and it may carry out the functions of Yeast Rsc-1 and Rsc-2. ...
    cd05517
    Location:203 → 305
    Bromo_polybromo_II; Bromodomain, polybromo repeat II. Polybromo is a nuclear protein of unknown function, which contains 6 bromodomains. The human ortholog BAF180 is part of a SWI/SNF chromatin-remodeling complex, and it may carry out the functions of Yeast Rsc-1 and Rsc-2. ...
    cd05518
    Location:540 → 643
    Bromo_polybromo_IV; Bromodomain, polybromo repeat IV. Polybromo is a nuclear protein of unknown function, which contains 6 bromodomains. The human ortholog BAF180 is part of a SWI/SNF chromatin-remodeling complex, and it may carry out the functions of Yeast Rsc-1 and Rsc-2. ...
    cd05520
    Location:404 → 505
    Bromo_polybromo_III; Bromodomain, polybromo repeat III. Polybromo is a nuclear protein of unknown function, which contains 6 bromodomains. The human ortholog BAF180 is part of a SWI/SNF chromatin-remodeling complex, and it may carry out the functions of Yeast Rsc-1 and Rsc-2. ...
    cd05524
    Location:65 → 177
    Bromo_polybromo_I; Bromodomain, polybromo repeat I. Polybromo is a nuclear protein of unknown function, which contains 6 bromodomains. The human ortholog BAF180 is part of a SWI/SNF chromatin-remodeling complex, and it may carry out the functions of Yeast Rsc-1 and Rsc-2. ...
    cd05526
    Location:796 → 903
    Bromo_polybromo_VI; Bromodomain, polybromo repeat VI. Polybromo is a nuclear protein of unknown function, which contains 6 bromodomains. The human ortholog BAF180 is part of a SWI/SNF chromatin-remodeling complex, and it may carry out the functions of Yeast Rsc-1 and Rsc-2. ...
    cd00084
    Location:1401 → 1465
    HMG-box; High Mobility Group (HMG)-box is found in a variety of eukaryotic chromosomal proteins and transcription factors. HMGs bind to the minor groove of DNA and have been classified by DNA binding preferences. Two phylogenically distinct groups of Class I ...
    cd04717
    Location:978 → 1095
    BAH_polybromo; BAH, or Bromo Adjacent Homology domain, as present in polybromo and yeast RSC1/2. The human polybromo protein (BAF180) is a component of the SWI/SNF chromatin-remodeling complex PBAF. It is thought that polybromo participates in transcriptional ...

  29. XM_011533903.4 → XP_011532205.1  protein polybromo-1 isoform X5

    See identical proteins and their annotated locations for XP_011532205.1

    UniProtKB/TrEMBL
    E7EVG2
    Conserved Domains (8) summary
    cd05515
    Location:694 → 798
    Bromo_polybromo_V; Bromodomain, polybromo repeat V. Polybromo is a nuclear protein of unknown function, which contains 6 bromodomains. The human ortholog BAF180 is part of a SWI/SNF chromatin-remodeling complex, and it may carry out the functions of Yeast Rsc-1 and Rsc-2. ...
    cd05517
    Location:203 → 305
    Bromo_polybromo_II; Bromodomain, polybromo repeat II. Polybromo is a nuclear protein of unknown function, which contains 6 bromodomains. The human ortholog BAF180 is part of a SWI/SNF chromatin-remodeling complex, and it may carry out the functions of Yeast Rsc-1 and Rsc-2. ...
    cd05518
    Location:555 → 658
    Bromo_polybromo_IV; Bromodomain, polybromo repeat IV. Polybromo is a nuclear protein of unknown function, which contains 6 bromodomains. The human ortholog BAF180 is part of a SWI/SNF chromatin-remodeling complex, and it may carry out the functions of Yeast Rsc-1 and Rsc-2. ...
    cd05520
    Location:404 → 505
    Bromo_polybromo_III; Bromodomain, polybromo repeat III. Polybromo is a nuclear protein of unknown function, which contains 6 bromodomains. The human ortholog BAF180 is part of a SWI/SNF chromatin-remodeling complex, and it may carry out the functions of Yeast Rsc-1 and Rsc-2. ...
    cd05524
    Location:65 → 177
    Bromo_polybromo_I; Bromodomain, polybromo repeat I. Polybromo is a nuclear protein of unknown function, which contains 6 bromodomains. The human ortholog BAF180 is part of a SWI/SNF chromatin-remodeling complex, and it may carry out the functions of Yeast Rsc-1 and Rsc-2. ...
    cd05526
    Location:811 → 918
    Bromo_polybromo_VI; Bromodomain, polybromo repeat VI. Polybromo is a nuclear protein of unknown function, which contains 6 bromodomains. The human ortholog BAF180 is part of a SWI/SNF chromatin-remodeling complex, and it may carry out the functions of Yeast Rsc-1 and Rsc-2. ...
    cd00084
    Location:1416 → 1480
    HMG-box; High Mobility Group (HMG)-box is found in a variety of eukaryotic chromosomal proteins and transcription factors. HMGs bind to the minor groove of DNA and have been classified by DNA binding preferences. Two phylogenically distinct groups of Class I ...
    cd04717
    Location:993 → 1110
    BAH_polybromo; BAH, or Bromo Adjacent Homology domain, as present in polybromo and yeast RSC1/2. The human polybromo protein (BAF180) is a component of the SWI/SNF chromatin-remodeling complex PBAF. It is thought that polybromo participates in transcriptional ...

  30. XM_017006728.2 → XP_016862217.1  protein polybromo-1 isoform X1

    UniProtKB/TrEMBL
    E7EVG2

  31. XM_047448454.1 → XP_047304410.1  protein polybromo-1 isoform X15

  32. XM_011533900.4 → XP_011532202.1  protein polybromo-1 isoform X5

    See identical proteins and their annotated locations for XP_011532202.1

    UniProtKB/TrEMBL
    E7EVG2
    Conserved Domains (8) summary
    cd05515
    Location:694 → 798
    Bromo_polybromo_V; Bromodomain, polybromo repeat V. Polybromo is a nuclear protein of unknown function, which contains 6 bromodomains. The human ortholog BAF180 is part of a SWI/SNF chromatin-remodeling complex, and it may carry out the functions of Yeast Rsc-1 and Rsc-2. ...
    cd05517
    Location:203 → 305
    Bromo_polybromo_II; Bromodomain, polybromo repeat II. Polybromo is a nuclear protein of unknown function, which contains 6 bromodomains. The human ortholog BAF180 is part of a SWI/SNF chromatin-remodeling complex, and it may carry out the functions of Yeast Rsc-1 and Rsc-2. ...
    cd05518
    Location:555 → 658
    Bromo_polybromo_IV; Bromodomain, polybromo repeat IV. Polybromo is a nuclear protein of unknown function, which contains 6 bromodomains. The human ortholog BAF180 is part of a SWI/SNF chromatin-remodeling complex, and it may carry out the functions of Yeast Rsc-1 and Rsc-2. ...
    cd05520
    Location:404 → 505
    Bromo_polybromo_III; Bromodomain, polybromo repeat III. Polybromo is a nuclear protein of unknown function, which contains 6 bromodomains. The human ortholog BAF180 is part of a SWI/SNF chromatin-remodeling complex, and it may carry out the functions of Yeast Rsc-1 and Rsc-2. ...
    cd05524
    Location:65 → 177
    Bromo_polybromo_I; Bromodomain, polybromo repeat I. Polybromo is a nuclear protein of unknown function, which contains 6 bromodomains. The human ortholog BAF180 is part of a SWI/SNF chromatin-remodeling complex, and it may carry out the functions of Yeast Rsc-1 and Rsc-2. ...
    cd05526
    Location:811 → 918
    Bromo_polybromo_VI; Bromodomain, polybromo repeat VI. Polybromo is a nuclear protein of unknown function, which contains 6 bromodomains. The human ortholog BAF180 is part of a SWI/SNF chromatin-remodeling complex, and it may carry out the functions of Yeast Rsc-1 and Rsc-2. ...
    cd00084
    Location:1416 → 1480
    HMG-box; High Mobility Group (HMG)-box is found in a variety of eukaryotic chromosomal proteins and transcription factors. HMGs bind to the minor groove of DNA and have been classified by DNA binding preferences. Two phylogenically distinct groups of Class I ...
    cd04717
    Location:993 → 1110
    BAH_polybromo; BAH, or Bromo Adjacent Homology domain, as present in polybromo and yeast RSC1/2. The human polybromo protein (BAF180) is a component of the SWI/SNF chromatin-remodeling complex PBAF. It is thought that polybromo participates in transcriptional ...

  33. XM_017006726.2 → XP_016862215.1  protein polybromo-1 isoform X1

    UniProtKB/TrEMBL
    E7EVG2

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060927.1 Alternate T2T-CHM13v2.0

    Range
    52578272..52718824 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_054347105.1 → XP_054203080.1  protein polybromo-1 isoform X19

  2. XM_054347106.1 → XP_054203081.1  protein polybromo-1 isoform X20

  3. XM_054347092.1 → XP_054203067.1  protein polybromo-1 isoform X9

  4. XM_054347091.1 → XP_054203066.1  protein polybromo-1 isoform X8

  5. XM_054347083.1 → XP_054203058.1  protein polybromo-1 isoform X4

  6. XM_054347097.1 → XP_054203072.1  protein polybromo-1 isoform X13

  7. XM_054347090.1 → XP_054203065.1  protein polybromo-1 isoform X7

  8. XM_054347103.1 → XP_054203078.1  protein polybromo-1 isoform X17

  9. XM_054347093.1 → XP_054203068.1  protein polybromo-1 isoform X10

  10. XM_054347086.1 → XP_054203061.1  protein polybromo-1 isoform X5

  11. XM_054347075.1 → XP_054203050.1  protein polybromo-1 isoform X1

  12. XM_054347101.1 → XP_054203076.1  protein polybromo-1 isoform X15

  13. XM_054347081.1 → XP_054203056.1  protein polybromo-1 isoform X3

  14. XM_054347088.1 → XP_054203063.1  protein polybromo-1 isoform X5

  15. XM_054347078.1 → XP_054203053.1  protein polybromo-1 isoform X1

  16. XM_054347082.1 → XP_054203057.1  protein polybromo-1 isoform X4

  17. XM_054347089.1 → XP_054203064.1  protein polybromo-1 isoform X6

  18. XM_054347102.1 → XP_054203077.1  protein polybromo-1 isoform X16

  19. XM_054347084.1 → XP_054203059.1  protein polybromo-1 isoform X5

  20. XM_054347096.1 → XP_054203071.1  protein polybromo-1 isoform X12

  21. XM_054347079.1 → XP_054203054.1  protein polybromo-1 isoform X2

  22. XM_054347095.1 → XP_054203070.1  protein polybromo-1 isoform X11

  23. XM_054347074.1 → XP_054203049.1  protein polybromo-1 isoform X1

  24. XM_054347104.1 → XP_054203079.1  protein polybromo-1 isoform X18

  25. XM_054347099.1 → XP_054203074.1  protein polybromo-1 isoform X14

  26. XM_054347098.1 → XP_054203073.1  protein polybromo-1 isoform X13

  27. XM_054347080.1 → XP_054203055.1  protein polybromo-1 isoform X3

  28. XM_054347094.1 → XP_054203069.1  protein polybromo-1 isoform X10

  29. XM_054347085.1 → XP_054203060.1  protein polybromo-1 isoform X5

  30. XM_054347076.1 → XP_054203051.1  protein polybromo-1 isoform X1

  31. XM_054347100.1 → XP_054203075.1  protein polybromo-1 isoform X15

  32. XM_054347087.1 → XP_054203062.1  protein polybromo-1 isoform X5

  33. XM_054347077.1 → XP_054203052.1  protein polybromo-1 isoform X1

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_181041.1: Suppressed sequence

    Description
    NM_181041.1: This RefSeq was permanently suppressed because it is a nonsense-mediated mRNA decay (NMD) candidate.
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q86U86.1 GenPept UniProtKB/Swiss-Prot:Q86U86

Gene LinkOut

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