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cldn8.2 claudin 8.2 [ Danio rerio (zebrafish) ]

Gene ID: 550497, updated on 27-Mar-2024

Summary

Official Symbol
cldn8.2provided by ZNC
Official Full Name
claudin 8.2provided by ZNC
Primary source
ZFIN:ZDB-GENE-050417-331
See related
Ensembl:ENSDARG00000040628 AllianceGenome:ZFIN:ZDB-GENE-050417-331
Gene type
protein coding
RefSeq status
PREDICTED
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
cldn8d; sb:cb574; zgc:110333
Summary
Predicted to enable structural molecule activity. Predicted to be involved in bicellular tight junction assembly and cell adhesion. Predicted to be located in cell junction and membrane. Predicted to be integral component of membrane. Predicted to be active in bicellular tight junction and plasma membrane. Is expressed in several structures, including EVL; epidermis; gill; periderm; and spleen. Orthologous to human CLDN17 (claudin 17). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
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Genomic context

Location:
chromosome: 15
Exon count:
4
Annotation release Status Assembly Chr Location
106 current GRCz11 (GCF_000002035.6) 15 NC_007126.7 (42560354..42575210)
105 previous assembly GRCz10 (GCF_000002035.5) 15 NC_007126.6 (42604012..42618868)

Chromosome 15 - NC_007126.7Genomic Context describing neighboring genes Neighboring gene SR-related CTD-associated factor 4b Neighboring gene TIAM Rac1 associated GEF 1b Neighboring gene claudin 8.3 Neighboring gene uncharacterized LOC103908871 Neighboring gene claudin 8.1

Genomic regions, transcripts, and products

Expression

  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

General gene information

Markers

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables structural molecule activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in bicellular tight junction assembly IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in cell adhesion IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
located_in anchoring junction IEA
Inferred from Electronic Annotation
more info
 
is_active_in bicellular tight junction IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in bicellular tight junction IEA
Inferred from Electronic Annotation
more info
 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
 

General protein information

Preferred Names
uncharacterized protein LOC550497
Names
claudin 8-like

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001017799.2NP_001017799.1  uncharacterized protein LOC550497

    See identical proteins and their annotated locations for NP_001017799.1

    Status: PREDICTED

    Source sequence(s)
    BC129277
    UniProtKB/TrEMBL
    A1L1Z4, F6P0L2, Q568F1
    Related
    ENSDARP00000059483.5, ENSDART00000059484.7
    Conserved Domains (1) summary
    cl21598
    Location:62236
    PMP22_Claudin; PMP-22/EMP/MP20/Claudin family

RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007126.7 Reference GRCz11 Primary Assembly

    Range
    42560354..42575210
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)