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ADAMTS17 ADAM metallopeptidase with thrombospondin type 1 motif 17 [ Bos taurus (cattle) ]

Gene ID: 538131, updated on 5-Mar-2024

Summary

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Official Symbol
ADAMTS17provided by VGNC
Official Full Name
ADAM metallopeptidase with thrombospondin type 1 motif 17provided by VGNC
Primary source
VGNC:VGNC:25621
See related
BGD:BT18250; Ensembl:ENSBTAG00000019823
Gene type
protein coding
RefSeq status
MODEL
Organism
Bos taurus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 21
Exon count:
23
Annotation release Status Assembly Chr Location
RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 21 NC_037348.1 (6331736..6741921)

Chromosome 21 - NC_037348.1Genomic Context describing neighboring genes Neighboring gene ceramide synthase 3 Neighboring gene uncharacterized LOC132343324 Neighboring gene small ribosomal subunit protein uS3-like Neighboring gene uncharacterized LOC132343325 Neighboring gene LysM domain containing 4 Neighboring gene myocyte enhancer factor 2A

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_037348.1 Chromosome 21 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables metalloendopeptidase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in extracellular matrix organization IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in proteolysis IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in extracellular matrix IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
A disintegrin and metalloproteinase with thrombospondin motifs 17

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UCD2.0 Primary Assembly

Genomic

  1. NC_037348.1 Reference ARS-UCD2.0 Primary Assembly

    Range
    6331736..6741921
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_024982263.2 → XP_024838031.1  A disintegrin and metalloproteinase with thrombospondin motifs 17 isoform X3

    UniProtKB/TrEMBL
    E1B6Z9
    Conserved Domains (6) summary
    smart00209
    Location:528 → 580
    TSP1; Thrombospondin type 1 repeats
    cd04273
    Location:228 → 430
    ZnMc_ADAMTS_like; Zinc-dependent metalloprotease, ADAMTS_like subgroup. ADAMs (A Disintegrin And Metalloprotease) are glycoproteins, which play roles in cell signaling, cell fusion, and cell-cell interactions. This particular subfamily represents domain architectures that ...
    pfam00090
    Location:877 → 930
    TSP_1; Thrombospondin type 1 domain
    pfam01562
    Location:81 → 176
    Pep_M12B_propep; Reprolysin family propeptide
    pfam05986
    Location:682 → 792
    ADAM_spacer1; ADAM-TS Spacer 1
    pfam08686
    Location:1064 → 1090
    PLAC; PLAC (protease and lacunin) domain

  2. XM_024982261.2 → XP_024838029.1  A disintegrin and metalloproteinase with thrombospondin motifs 17 isoform X1

    UniProtKB/TrEMBL
    E1B6Z9
    Conserved Domains (6) summary
    smart00209
    Location:543 → 595
    TSP1; Thrombospondin type 1 repeats
    cd04273
    Location:228 → 445
    ZnMc_ADAMTS_like; Zinc-dependent metalloprotease, ADAMTS_like subgroup. ADAMs (A Disintegrin And Metalloprotease) are glycoproteins, which play roles in cell signaling, cell fusion, and cell-cell interactions. This particular subfamily represents domain architectures that ...
    pfam00090
    Location:892 → 945
    TSP_1; Thrombospondin type 1 domain
    pfam01562
    Location:81 → 176
    Pep_M12B_propep; Reprolysin family propeptide
    pfam05986
    Location:697 → 807
    ADAM_spacer1; ADAM-TS Spacer 1
    pfam08686
    Location:1079 → 1105
    PLAC; PLAC (protease and lacunin) domain

  3. XM_024982262.2 → XP_024838030.1  A disintegrin and metalloproteinase with thrombospondin motifs 17 isoform X2

    UniProtKB/TrEMBL
    E1B6Z9
    Related
    ENSBTAP00000073228.2, ENSBTAT00000079673.2
    Conserved Domains (6) summary
    smart00209
    Location:542 → 594
    TSP1; Thrombospondin type 1 repeats
    cd04273
    Location:228 → 445
    ZnMc_ADAMTS_like; Zinc-dependent metalloprotease, ADAMTS_like subgroup. ADAMs (A Disintegrin And Metalloprotease) are glycoproteins, which play roles in cell signaling, cell fusion, and cell-cell interactions. This particular subfamily represents domain architectures that ...
    pfam00090
    Location:891 → 944
    TSP_1; Thrombospondin type 1 domain
    pfam01562
    Location:81 → 176
    Pep_M12B_propep; Reprolysin family propeptide
    pfam05986
    Location:696 → 806
    ADAM_spacer1; ADAM-TS Spacer 1
    pfam08686
    Location:1078 → 1104
    PLAC; PLAC (protease and lacunin) domain
Nucleotide Protein Strain
Heading Accession and Version

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