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fut10 fucosyltransferase 10 [ Danio rerio (zebrafish) ]

Gene ID: 497615, updated on 27-Mar-2024

Summary

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Official Symbol
fut10provided by ZNC
Official Full Name
fucosyltransferase 10provided by ZNC
Primary source
ZFIN:ZDB-GENE-081022-183
See related
Ensembl:ENSDARG00000100322 AllianceGenome:ZFIN:ZDB-GENE-081022-183
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
zgc:195147
Summary
Predicted to enable alpha-(1->3)-fucosyltransferase activity. Predicted to be involved in fucosylation. Predicted to be located in Golgi cisterna membrane and Golgi membrane. Predicted to be integral component of membrane. Orthologous to human FUT10 (fucosyltransferase 10). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 10
Exon count:
5
Annotation release Status Assembly Chr Location
106 current GRCz11 (GCF_000002035.6) 10 NC_007121.7 (7255533..7264913)
105 previous assembly GRCz10 (GCF_000002035.5) 10 NC_007121.6 (7296770..7306267)

Chromosome 10 - NC_007121.7Genomic Context describing neighboring genes Neighboring gene SH2 domain containing 4A Neighboring gene pleckstrin and Sec7 domain containing 3, like Neighboring gene neuregulin 1 Neighboring gene WRN RecQ like helicase

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. The rapid generation of chimerical genes expanding protein diversity in zebrafish. Fu B, et al. BMC Genomics, 2010 Nov 24. PMID 21106061, Free PMC Article
  2. Metabolic labeling of fucosylated glycans in developing zebrafish. Dehnert KW, et al. ACS Chem Biol, 2011 Jun 17. PMID 21425872, Free PMC Article
  3. Activity, splice variants, conserved peptide motifs, and phylogeny of two new alpha1,3-fucosyltransferase families (FUT10 and FUT11). Mollicone R, et al. J Biol Chem, 2009 Feb 13. PMID 19088067
  4. Neuroepithelial cells require fucosylated glycans to guide the migration of vagus motor neuron progenitors in the developing zebrafish hindbrain. Ohata S, et al. Development, 2009 May. PMID 19369395
  5. Mapping the expressed glycome and glycosyltransferases of zebrafish liver cells as a relevant model system for glycosylation studies. Vanbeselaere J, et al. J Proteome Res, 2012 Apr 6. PMID 22352757

See all (8) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables alpha-(1->3)-fucosyltransferase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables alpha-(1->3)-fucosyltransferase activity IEA
Inferred from Electronic Annotation
more info
  
enables fucosyltransferase activity IEA
Inferred from Electronic Annotation
more info
  
enables glycosyltransferase activity IEA
Inferred from Electronic Annotation
more info
  
enables hexosyltransferase activity IEA
Inferred from Electronic Annotation
more info
  
enables transferase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in fucosylation IBA
Inferred from Biological aspect of Ancestor
more info
  
acts_upstream_of_or_within protein glycosylation IEA
Inferred from Electronic Annotation
more info
  
involved_in protein glycosylation IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in Golgi apparatus IEA
Inferred from Electronic Annotation
more info
  
located_in Golgi cisterna membrane IEA
Inferred from Electronic Annotation
more info
  
located_in Golgi membrane IEA
Inferred from Electronic Annotation
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
alpha-(1,3)-fucosyltransferase 10
Names
alpha3-fucosyltransferase
fuc-TX
fucT-X
fucosyltransferase X
galactoside 3-L-fucosyltransferase 10
NP_001012374.1
XP_005155519.1
XP_009295708.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001012374.1 → NP_001012374.1  alpha-(1,3)-fucosyltransferase 10

    See identical proteins and their annotated locations for NP_001012374.1

    Status: PROVISIONAL

    Source sequence(s)
    AJ879586
    UniProtKB/Swiss-Prot
    B3DIM2, Q5F2N3
    UniProtKB/TrEMBL
    A0A2R8QLF1
    Related
    ENSDARP00000155202.1, ENSDART00000181304.1
    Conserved Domains (2) summary
    pfam00852
    Location:198 → 339
    Glyco_transf_10; Glycosyltransferase family 10 (fucosyltransferase) C-term
    pfam17039
    Location:67 → 162
    Glyco_tran_10_N; Fucosyltransferase, N-terminal

RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007121.7 Reference GRCz11 Primary Assembly

    Range
    7255533..7264913
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005155462.4 → XP_005155519.1  alpha-(1,3)-fucosyltransferase 10 isoform X1

    UniProtKB/Swiss-Prot
    B3DIM2, Q5F2N3
    UniProtKB/TrEMBL
    A0A8M2B1Y6
    Related
    ENSDARP00000135630.2, ENSDART00000161506.3
    Conserved Domains (2) summary
    pfam00852
    Location:201 → 342
    Glyco_transf_10; Glycosyltransferase family 10 (fucosyltransferase) C-term
    pfam17039
    Location:70 → 165
    Glyco_tran_10_N; Fucosyltransferase, N-terminal

  2. XM_009297433.3 → XP_009295708.1  alpha-(1,3)-fucosyltransferase 10 isoform X2

    UniProtKB/TrEMBL
    A0A8M3AP91
    Conserved Domains (1) summary
    pfam00852
    Location:1 → 120
    Glyco_transf_10; Glycosyltransferase family 10 (fucosyltransferase) C-term
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q5F2N3.3 GenPept UniProtKB/Swiss-Prot:Q5F2N3

Gene LinkOut

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