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pih1d2 PIH1 domain containing 2 [ Danio rerio (zebrafish) ]

Gene ID: 494086, updated on 27-Mar-2024

Summary

Official Symbol
pih1d2provided by ZNC
Official Full Name
PIH1 domain containing 2provided by ZNC
Primary source
ZFIN:ZDB-GENE-041212-54
See related
Ensembl:ENSDARG00000014849 AllianceGenome:ZFIN:ZDB-GENE-041212-54
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
zgc:101725
Summary
Acts upstream of or within axonemal dynein complex assembly. Predicted to be part of R2TP complex and ribonucleoprotein complex. Predicted to be active in cytoplasm. Is expressed in Kupffer's vesicle; floor plate; otic placode; and pronephric duct. Orthologous to human PIH1D2 (PIH1 domain containing 2). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
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Genomic context

See pih1d2 in Genome Data Viewer
Location:
chromosome: 15
Exon count:
7
Annotation release Status Assembly Chr Location
106 current GRCz11 (GCF_000002035.6) 15 NC_007126.7 (18138518..18162650, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 15 NC_007126.6 (18202496..18226628, complement)

Chromosome 15 - NC_007126.7Genomic Context describing neighboring genes Neighboring gene archain 1b Neighboring gene crystallin, alpha B, a Neighboring gene DIX domain containing 1a Neighboring gene transmembrane serine protease 5 Neighboring gene bloodthirsty-related gene family, member 14

Genomic regions, transcripts, and products

Expression

  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

General gene information

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
 
Process Evidence Code Pubs
acts_upstream_of_or_within axonemal dynein complex assembly IGI
Inferred from Genetic Interaction
more info
PubMed 
acts_upstream_of_or_within axonemal dynein complex assembly IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in box C/D snoRNP assembly IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in rRNA processing IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
part_of R2TP complex IBA
Inferred from Biological aspect of Ancestor
more info
 
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
 
part_of ribonucleoprotein complex IBA
Inferred from Biological aspect of Ancestor
more info
 

General protein information

Preferred Names
PIH1 domain-containing protein 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001008629.1NP_001008629.1  PIH1 domain-containing protein 2

    See identical proteins and their annotated locations for NP_001008629.1

    Status: PROVISIONAL

    Source sequence(s)
    BC086728
    UniProtKB/Swiss-Prot
    Q5PRB3
    Related
    ENSDARP00000017232.6, ENSDART00000012064.7
    Conserved Domains (1) summary
    cl00175
    Location:51321
    alpha-crystallin-Hsps_p23-like; alpha-crystallin domain (ACD) found in alpha-crystallin-type small heat shock proteins, and a similar domain found in p23 (a cochaperone for Hsp90) and in other p23-like proteins.

RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007126.7 Reference GRCz11 Primary Assembly

    Range
    18138518..18162650 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_009291562.1XP_009289837.1  PIH1 domain-containing protein 2 isoform X1

    UniProtKB/TrEMBL
    A0A8M3B0W4
    Conserved Domains (1) summary
    cl00175
    Location:51318
    alpha-crystallin-Hsps_p23-like; alpha-crystallin domain (ACD) found in alpha-crystallin-type small heat shock proteins, and a similar domain found in p23 (a cochaperone for Hsp90) and in other p23-like proteins.
  2. XM_021481402.1XP_021337077.1  PIH1 domain-containing protein 2 isoform X3

    UniProtKB/TrEMBL
    A0A8M9Q0C7
    Conserved Domains (1) summary
    cl00175
    Location:51220
    alpha-crystallin-Hsps_p23-like; alpha-crystallin domain (ACD) found in alpha-crystallin-type small heat shock proteins, and a similar domain found in p23 (a cochaperone for Hsp90) and in other p23-like proteins.
  3. XM_021481399.1XP_021337074.1  PIH1 domain-containing protein 2 isoform X2

    UniProtKB/TrEMBL
    A0A8M9QH82
    Conserved Domains (1) summary
    cl00175
    Location:51279
    alpha-crystallin-Hsps_p23-like; alpha-crystallin domain (ACD) found in alpha-crystallin-type small heat shock proteins, and a similar domain found in p23 (a cochaperone for Hsp90) and in other p23-like proteins.
  4. XM_021481403.1XP_021337078.1  PIH1 domain-containing protein 2 isoform X4

    UniProtKB/TrEMBL
    A0A8M9QBZ8
    Conserved Domains (1) summary
    cl00175
    Location:13223
    alpha-crystallin-Hsps_p23-like; alpha-crystallin domain (ACD) found in alpha-crystallin-type small heat shock proteins, and a similar domain found in p23 (a cochaperone for Hsp90) and in other p23-like proteins.
  5. XM_021481401.1XP_021337076.1  PIH1 domain-containing protein 2 isoform X3

    UniProtKB/TrEMBL
    A0A8M9Q0C7
    Conserved Domains (1) summary
    cl00175
    Location:51220
    alpha-crystallin-Hsps_p23-like; alpha-crystallin domain (ACD) found in alpha-crystallin-type small heat shock proteins, and a similar domain found in p23 (a cochaperone for Hsp90) and in other p23-like proteins.