katnal1 katanin p60 subunit A-like 1 [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: katnal1provided by ZNC
Official Full Name: katanin p60 subunit A-like 1provided by ZNC
Primary source: ZFIN:ZDB-GENE-041114-141
See related: Ensembl:ENSDARG00000099156 AllianceGenome:ZFIN:ZDB-GENE-041114-141
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: zgc:101696
Summary: Predicted to enable several functions, including ATP binding activity; microtubule binding activity; and microtubule-severing ATPase activity. Predicted to be involved in microtubule severing. Predicted to act upstream of or within cell division. Predicted to be located in cytoplasm; microtubule; and spindle pole. Predicted to be active in microtubule cytoskeleton. Is expressed in nervous system and yolk syncytial layer. Orthologous to human KATNAL1 (katanin catalytic subunit A1 like 1). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs: all
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Genomic context

Location:: chromosome: 10

Exon count:: 11

Annotation release	Status	Assembly	Chr	Location
106	current	GRCz11 (GCF_000002035.6)	10	NC_007121.7 (36037977..36063415)
105	previous assembly	GRCz10 (GCF_000002035.5)	10	NC_007121.6 (36094219..36119657)

Chromosome 10 - NC_007121.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables ATP binding	IEA Inferred from Electronic Annotation more info
enables ATP hydrolysis activity	IBA Inferred from Biological aspect of Ancestor more info
enables ATP hydrolysis activity	IEA Inferred from Electronic Annotation more info
enables isomerase activity	IEA Inferred from Electronic Annotation more info
enables microtubule binding	IEA Inferred from Electronic Annotation more info
enables microtubule severing ATPase activity	IEA Inferred from Electronic Annotation more info
enables nucleotide binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in microtubule severing	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within microtubule severing	IEA Inferred from Electronic Annotation more info
involved_in spermatogenesis	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in centrosome	IEA Inferred from Electronic Annotation more info
located_in cytoplasm	IEA Inferred from Electronic Annotation more info
located_in cytoplasm	ISS Inferred from Sequence or Structural Similarity more info
located_in cytoskeleton	IEA Inferred from Electronic Annotation more info
located_in microtubule	IEA Inferred from Electronic Annotation more info
located_in microtubule	ISS Inferred from Sequence or Structural Similarity more info
is_active_in microtubule cytoskeleton	IBA Inferred from Biological aspect of Ancestor more info
located_in spindle pole	ISS Inferred from Sequence or Structural Similarity more info

General protein information

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Preferred Names: katanin p60 ATPase-containing subunit A-like 1

NP_001007432.1

EC 5.6.1.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001007431.1 → NP_001007432.1 katanin p60 ATPase-containing subunit A-like 1

See identical proteins and their annotated locations for NP_001007432.1

Status: PROVISIONAL

Source sequence(s)

BC085416

UniProtKB/Swiss-Prot

Q5U3S1

Related

ENSDARP00000131532.1, ENSDART00000164678.2

Conserved Domains (3) summary

smart00382
Location:238 → 380

AAA; ATPases associated with a variety of cellular activities

pfam00004
Location:242 → 378

AAA; ATPase family associated with various cellular activities (AAA)

pfam09336
Location:448 → 486

Vps4_C; Vps4 C terminal oligomerization domain