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DPH6 diphthamine biosynthesis 6 [ Canis lupus familiaris (dog) ]

Gene ID: 487480, updated on 5-Mar-2024

Summary

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Official Symbol
DPH6provided by VGNC
Official Full Name
diphthamine biosynthesis 6provided by VGNC
Primary source
VGNC:VGNC:58300
See related
Ensembl:ENSCAFG00845024177
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Also known as
ATPBD4
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 30
Exon count:
20
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 30 NC_051834.1 (3066202..3261206, complement)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 30 NC_006612.4 (3000875..3196175, complement)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 30 NC_049251.1 (3228666..3423950, complement)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 30 NC_049290.1 (2999857..3195107, complement)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 30 NC_049771.1 (3099636..3295078, complement)

Chromosome 30 - NC_051834.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC111093376 Neighboring gene uncharacterized LOC119866858 Neighboring gene zinc finger protein 770 Neighboring gene uncharacterized LOC111093329 Neighboring gene cytochrome c oxidase subunit 5A, mitochondrial-like Neighboring gene uncharacterized LOC119866859 Neighboring gene microRNA mir-8792

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables diphthine-ammonia ligase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in protein histidyl modification to diphthamide IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
diphthine--ammonia ligase
Names
ATP binding domain 4
XP_038297825.1
XP_038297826.1
XP_038297828.1
XP_038297829.1
XP_038297830.1
XP_038317555.1
XP_038317556.1
XP_038317557.1
XP_038317558.1
XP_038317559.1
XP_038372307.1
XP_038372308.1
XP_038372309.1
XP_038372310.1
XP_038372311.1
XP_038435902.1
XP_038435903.1
XP_038435904.1
XP_038435905.1
XP_038435906.1
XP_038500164.1
XP_038500165.1
XP_038500167.1
XP_038500168.1
XP_038500169.1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051834.1 Reference ROS_Cfam_1.0

    Range
    3066202..3261206 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038441897.1 → XP_038297825.1  diphthine--ammonia ligase isoform X1

    UniProtKB/TrEMBL
    A0A8C0K028, A0A8I3PHH9, A0A8P0SDP1
    Conserved Domains (1) summary
    cd01994
    Location:2 → 215
    Alpha_ANH_like_IV; This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases superfamily includes N type ATP PPases and ATP sulphurylases. It forms a apha/beta/apha fold which binds to Adenosine group. This subfamily ...

  2. XM_038441900.1 → XP_038297828.1  diphthine--ammonia ligase isoform X3

    UniProtKB/TrEMBL
    A0A8C0K028, A0A8I3PHH9, A0A8P0SDP1
    Conserved Domains (1) summary
    cd01994
    Location:1 → 199
    Alpha_ANH_like_IV; This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases superfamily includes N type ATP PPases and ATP sulphurylases. It forms a apha/beta/apha fold which binds to Adenosine group. This subfamily ...

  3. XM_038441901.1 → XP_038297829.1  diphthine--ammonia ligase isoform X3

    UniProtKB/TrEMBL
    A0A8C0K028, A0A8I3PHH9, A0A8P0SDP1
    Conserved Domains (1) summary
    cd01994
    Location:1 → 199
    Alpha_ANH_like_IV; This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases superfamily includes N type ATP PPases and ATP sulphurylases. It forms a apha/beta/apha fold which binds to Adenosine group. This subfamily ...

  4. XM_038441898.1 → XP_038297826.1  diphthine--ammonia ligase isoform X2

    UniProtKB/TrEMBL
    A0A8C0K028, A0A8C0PTQ2, A0A8I3PHH9, A0A8I3PL89, A0A8P0SDP1
    Related
    ENSCAFP00845033627.1, ENSCAFT00845042902.1
    Conserved Domains (1) summary
    cd01994
    Location:2 → 215
    Alpha_ANH_like_IV; This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases superfamily includes N type ATP PPases and ATP sulphurylases. It forms a apha/beta/apha fold which binds to Adenosine group. This subfamily ...

  5. XM_038441902.1 → XP_038297830.1  diphthine--ammonia ligase isoform X4

    UniProtKB/TrEMBL
    A0A8C0PH74, A0A8I3PM71
    Related
    ENSCAFP00845033699.1, ENSCAFT00845042985.1
    Conserved Domains (1) summary
    cl00292
    Location:2 → 104
    AANH_like; Adenine nucleotide alpha hydrolases superfamily including N type ATP PPases, ATP sulphurylases Universal Stress Response protein and electron transfer flavoprotein (ETF). The domain forms a apha/beta/apha fold which binds to Adenosine nucleotide.

RNA

  1. XR_005304611.1 RNA Sequence

  2. XR_005304612.1 RNA Sequence

  3. XR_005304613.1 RNA Sequence

  4. XR_005304614.1 RNA Sequence

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049290.1 Alternate UMICH_Zoey_3.1

    Range
    2999857..3195107 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038516379.1 → XP_038372307.1  diphthine--ammonia ligase isoform X1

    Conserved Domains (1) summary
    cd01994
    Location:2 → 215
    Alpha_ANH_like_IV; This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases superfamily includes N type ATP PPases and ATP sulphurylases. It forms a apha/beta/apha fold which binds to Adenosine group. This subfamily ...

  2. XM_038516381.1 → XP_038372309.1  diphthine--ammonia ligase isoform X3

    Conserved Domains (1) summary
    cd01994
    Location:1 → 199
    Alpha_ANH_like_IV; This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases superfamily includes N type ATP PPases and ATP sulphurylases. It forms a apha/beta/apha fold which binds to Adenosine group. This subfamily ...

  3. XM_038516382.1 → XP_038372310.1  diphthine--ammonia ligase isoform X3

    Conserved Domains (1) summary
    cd01994
    Location:1 → 199
    Alpha_ANH_like_IV; This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases superfamily includes N type ATP PPases and ATP sulphurylases. It forms a apha/beta/apha fold which binds to Adenosine group. This subfamily ...

  4. XM_038516380.1 → XP_038372308.1  diphthine--ammonia ligase isoform X2

    Conserved Domains (1) summary
    cd01994
    Location:2 → 215
    Alpha_ANH_like_IV; This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases superfamily includes N type ATP PPases and ATP sulphurylases. It forms a apha/beta/apha fold which binds to Adenosine group. This subfamily ...

  5. XM_038516383.1 → XP_038372311.1  diphthine--ammonia ligase isoform X4

    Conserved Domains (1) summary
    cl00292
    Location:2 → 104
    AANH_like; Adenine nucleotide alpha hydrolases superfamily including N type ATP PPases, ATP sulphurylases Universal Stress Response protein and electron transfer flavoprotein (ETF). The domain forms a apha/beta/apha fold which binds to Adenosine nucleotide.

RNA

  1. XR_005347686.1 RNA Sequence

  2. XR_005347687.1 RNA Sequence

  3. XR_005347688.1 RNA Sequence

  4. XR_005347689.1 RNA Sequence

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049771.1 Alternate UNSW_CanFamBas_1.0

    Range
    3099636..3295078 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038644236.1 → XP_038500164.1  diphthine--ammonia ligase isoform X1

    Conserved Domains (1) summary
    cd01994
    Location:2 → 215
    Alpha_ANH_like_IV; This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases superfamily includes N type ATP PPases and ATP sulphurylases. It forms a apha/beta/apha fold which binds to Adenosine group. This subfamily ...

  2. XM_038644239.1 → XP_038500167.1  diphthine--ammonia ligase isoform X3

    Conserved Domains (1) summary
    cd01994
    Location:1 → 199
    Alpha_ANH_like_IV; This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases superfamily includes N type ATP PPases and ATP sulphurylases. It forms a apha/beta/apha fold which binds to Adenosine group. This subfamily ...

  3. XM_038644240.1 → XP_038500168.1  diphthine--ammonia ligase isoform X3

    Conserved Domains (1) summary
    cd01994
    Location:1 → 199
    Alpha_ANH_like_IV; This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases superfamily includes N type ATP PPases and ATP sulphurylases. It forms a apha/beta/apha fold which binds to Adenosine group. This subfamily ...

  4. XM_038644237.1 → XP_038500165.1  diphthine--ammonia ligase isoform X2

    Conserved Domains (1) summary
    cd01994
    Location:2 → 215
    Alpha_ANH_like_IV; This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases superfamily includes N type ATP PPases and ATP sulphurylases. It forms a apha/beta/apha fold which binds to Adenosine group. This subfamily ...

  5. XM_038644241.1 → XP_038500169.1  diphthine--ammonia ligase isoform X4

    Conserved Domains (1) summary
    cl00292
    Location:2 → 104
    AANH_like; Adenine nucleotide alpha hydrolases superfamily including N type ATP PPases, ATP sulphurylases Universal Stress Response protein and electron transfer flavoprotein (ETF). The domain forms a apha/beta/apha fold which binds to Adenosine nucleotide.

RNA

  1. XR_005415245.1 RNA Sequence

  2. XR_005415246.1 RNA Sequence

  3. XR_005415247.1 RNA Sequence

  4. XR_005415248.1 RNA Sequence

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049251.1 Alternate UU_Cfam_GSD_1.0

    Range
    3228666..3423950 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038579974.1 → XP_038435902.1  diphthine--ammonia ligase isoform X1

    UniProtKB/TrEMBL
    A0A8C0K028, A0A8I3PHH9, A0A8P0SDP1
    Conserved Domains (1) summary
    cd01994
    Location:2 → 215
    Alpha_ANH_like_IV; This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases superfamily includes N type ATP PPases and ATP sulphurylases. It forms a apha/beta/apha fold which binds to Adenosine group. This subfamily ...

  2. XM_038579976.1 → XP_038435904.1  diphthine--ammonia ligase isoform X3

    UniProtKB/TrEMBL
    A0A8C0K028, A0A8I3PHH9, A0A8P0SDP1
    Conserved Domains (1) summary
    cd01994
    Location:1 → 199
    Alpha_ANH_like_IV; This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases superfamily includes N type ATP PPases and ATP sulphurylases. It forms a apha/beta/apha fold which binds to Adenosine group. This subfamily ...

  3. XM_038579977.1 → XP_038435905.1  diphthine--ammonia ligase isoform X3

    UniProtKB/TrEMBL
    A0A8C0K028, A0A8I3PHH9, A0A8P0SDP1
    Conserved Domains (1) summary
    cd01994
    Location:1 → 199
    Alpha_ANH_like_IV; This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases superfamily includes N type ATP PPases and ATP sulphurylases. It forms a apha/beta/apha fold which binds to Adenosine group. This subfamily ...

  4. XM_038579975.1 → XP_038435903.1  diphthine--ammonia ligase isoform X2

    UniProtKB/TrEMBL
    A0A8C0K028, A0A8C0PTQ2, A0A8I3PHH9, A0A8I3PL89, A0A8P0SDP1
    Conserved Domains (1) summary
    cd01994
    Location:2 → 215
    Alpha_ANH_like_IV; This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases superfamily includes N type ATP PPases and ATP sulphurylases. It forms a apha/beta/apha fold which binds to Adenosine group. This subfamily ...

  5. XM_038579978.1 → XP_038435906.1  diphthine--ammonia ligase isoform X4

    UniProtKB/TrEMBL
    A0A8C0PH74, A0A8I3PM71
    Conserved Domains (1) summary
    cl00292
    Location:2 → 104
    AANH_like; Adenine nucleotide alpha hydrolases superfamily including N type ATP PPases, ATP sulphurylases Universal Stress Response protein and electron transfer flavoprotein (ETF). The domain forms a apha/beta/apha fold which binds to Adenosine nucleotide.

RNA

  1. XR_005381426.1 RNA Sequence

  2. XR_005381427.1 RNA Sequence

  3. XR_005381428.1 RNA Sequence

  4. XR_005381429.1 RNA Sequence

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006612.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    3000875..3196175 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038461627.1 → XP_038317555.1  diphthine--ammonia ligase isoform X1

    UniProtKB/TrEMBL
    A0A8C0K028, A0A8I3PHH9, A0A8P0SDP1
    Conserved Domains (1) summary
    cd01994
    Location:2 → 215
    Alpha_ANH_like_IV; This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases superfamily includes N type ATP PPases and ATP sulphurylases. It forms a apha/beta/apha fold which binds to Adenosine group. This subfamily ...

  2. XM_038461629.1 → XP_038317557.1  diphthine--ammonia ligase isoform X3

    UniProtKB/TrEMBL
    A0A8C0K028, A0A8I3PHH9, A0A8P0SDP1
    Conserved Domains (1) summary
    cd01994
    Location:1 → 199
    Alpha_ANH_like_IV; This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases superfamily includes N type ATP PPases and ATP sulphurylases. It forms a apha/beta/apha fold which binds to Adenosine group. This subfamily ...

  3. XM_038461630.1 → XP_038317558.1  diphthine--ammonia ligase isoform X3

    UniProtKB/TrEMBL
    A0A8C0K028, A0A8I3PHH9, A0A8P0SDP1
    Conserved Domains (1) summary
    cd01994
    Location:1 → 199
    Alpha_ANH_like_IV; This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases superfamily includes N type ATP PPases and ATP sulphurylases. It forms a apha/beta/apha fold which binds to Adenosine group. This subfamily ...

  4. XM_038461628.1 → XP_038317556.1  diphthine--ammonia ligase isoform X2

    UniProtKB/TrEMBL
    A0A8C0K028, A0A8C0PTQ2, A0A8I3PHH9, A0A8I3PL89, A0A8P0SDP1
    Conserved Domains (1) summary
    cd01994
    Location:2 → 215
    Alpha_ANH_like_IV; This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases superfamily includes N type ATP PPases and ATP sulphurylases. It forms a apha/beta/apha fold which binds to Adenosine group. This subfamily ...

  5. XM_038461631.1 → XP_038317559.1  diphthine--ammonia ligase isoform X4

    UniProtKB/TrEMBL
    A0A8C0PH74, A0A8I3PM71
    Conserved Domains (1) summary
    cl00292
    Location:2 → 104
    AANH_like; Adenine nucleotide alpha hydrolases superfamily including N type ATP PPases, ATP sulphurylases Universal Stress Response protein and electron transfer flavoprotein (ETF). The domain forms a apha/beta/apha fold which binds to Adenosine nucleotide.

RNA

  1. XR_005316533.1 RNA Sequence

  2. XR_005316534.1 RNA Sequence

  3. XR_005316535.1 RNA Sequence

  4. XR_005316536.1 RNA Sequence

Nucleotide Protein
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