AMH anti-Mullerian hormone [Canis lupus familiaris (dog)] - Gene

Summary

Gene symbol: AMH
Gene description: anti-Mullerian hormone
See related: Ensembl:ENSCAFG00845012417
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Canis lupus familiaris (sub-species: familiaris)
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Also known as: Mis
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 20

Exon count:: 5

Annotation release	Status	Assembly	Chr	Location
106	current	ROS_Cfam_1.0 (GCF_014441545.1)	20	NC_051824.1 (57518896..57521686, complement)
106	current	Dog10K_Boxer_Tasha (GCF_000002285.5)	20	NC_006602.4 (56581099..56583889, complement)
106	current	UU_Cfam_GSD_1.0 (GCF_011100685.1)	20	NC_049241.1 (57256543..57259332, complement)
106	current	UMICH_Zoey_3.1 (GCF_005444595.1)	20	NC_049280.1 (56570917..56573707, complement)
106	current	UNSW_CanFamBas_1.0 (GCF_013276365.1)	20	NC_049761.1 (57056052..57058835, complement)

Chromosome 20 - NC_051824.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Anti-Mullerian hormone, testosterone, and insulin-like peptide 3 as biomarkers of Sertoli and Leydig cell function during deslorelin-induced testicular downregulation in the dog.
Title: Anti-Müllerian hormone, testosterone, and insulin-like peptide 3 as biomarkers of Sertoli and Leydig cell function during deslorelin-induced testicular downregulation in the dog.
sertoli cells (SC) from fetuses and puppies up to 45 days old expressed AMH, while SC from older puppies and adults were negative. All SC tumors expressed AMH, suggesting that AMH expression is a useful marker of immature and neoplastic canine SCs.
Title: Immunohistochemical evaluation of the expression of anti-Müllerian hormone in mature, immature and neoplastic canine Sertoli cells.

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General gene information

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Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables growth factor activity	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in Mullerian duct regression	IEA Inferred from Electronic Annotation more info	PubMed
involved_in gonad development	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in extracellular space	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: muellerian-inhibiting factor

Names: Mullerian inhibiting substance

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001314127.1 → NP_001301056.1 muellerian-inhibiting factor precursor

Status: PROVISIONAL

Source sequence(s)

KP223256

UniProtKB/TrEMBL

A0A0E3N0I3, A0A2H4UKA0, A0A8C0N2S3

Related

ENSCAFP00845017365.1, ENSCAFT00845022085.1

Conserved Domains (2) summary

cd13757
Location:473 → 572

TGF_beta_AMH; transforming growth factor beta (TGF-beta) like domain found in anti-Muellerian hormone (AMH) and similar proteins

pfam04709
Location:87 → 454

AMH_N; Anti-Mullerian hormone, N terminal region