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AMD1 adenosylmethionine decarboxylase 1 [ Canis lupus familiaris (dog) ]

Gene ID: 481960, updated on 5-Mar-2024

Summary

Official Symbol
AMD1provided by VGNC
Official Full Name
adenosylmethionine decarboxylase 1provided by VGNC
Primary source
VGNC:VGNC:37827
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
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Genomic context

Location:
chromosome: 12
Exon count:
11
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 12 NC_051816.1 (68311059..68331965)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 12 NC_006594.4 (67251123..67272026)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 12 NC_049233.1 (67786118..67807019)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 12 NC_049272.1 (67662003..67682902)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 12 NC_049753.1 (67507932..67528835)

Chromosome 12 - NC_051816.1Genomic Context describing neighboring genes Neighboring gene cyclin dependent kinase 19 Neighboring gene U6 spliceosomal RNA Neighboring gene uncharacterized LOC102153185 Neighboring gene U6 spliceosomal RNA Neighboring gene U4 spliceosomal RNA Neighboring gene uncharacterized LOC119874232 Neighboring gene general transcription factor IIIC subunit 6

Genomic regions, transcripts, and products

General gene information

Markers

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables adenosylmethionine decarboxylase activity IEA
Inferred from Electronic Annotation
more info
PubMed 
enables putrescine binding IEA
Inferred from Electronic Annotation
more info
PubMed 
Process Evidence Code Pubs
involved_in spermidine biosynthetic process IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in spermine biosynthetic process IEA
Inferred from Electronic Annotation
more info
PubMed 
Component Evidence Code Pubs
located_in cytosol IEA
Inferred from Electronic Annotation
more info
PubMed 

General protein information

Preferred Names
S-adenosylmethionine decarboxylase proenzyme
XP_005627768.2
XP_005627769.1
XP_022282159.1
XP_038348562.1
XP_038348563.1
XP_038348564.1
XP_038410879.1
XP_038410880.1
XP_038410882.1
XP_038474750.1
XP_038474751.1
XP_038474752.1
XP_038540301.1
XP_038540302.1
XP_038540303.1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051816.1 Reference ROS_Cfam_1.0

    Range
    68311059..68331965
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038684373.1XP_038540301.1  S-adenosylmethionine decarboxylase proenzyme isoform X1

    UniProtKB/TrEMBL
    A0A8C0L2E5, A0A8C0ME21
    Conserved Domains (1) summary
    pfam01536
    Location:4325
    SAM_decarbox; Adenosylmethionine decarboxylase
  2. XM_038684375.1XP_038540303.1  S-adenosylmethionine decarboxylase proenzyme isoform X2

    Conserved Domains (1) summary
    pfam01536
    Location:1256
    SAM_decarbox; Adenosylmethionine decarboxylase
  3. XM_038684374.1XP_038540302.1  S-adenosylmethionine decarboxylase proenzyme isoform X2

    Conserved Domains (1) summary
    pfam01536
    Location:1256
    SAM_decarbox; Adenosylmethionine decarboxylase

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049272.1 Alternate UMICH_Zoey_3.1

    Range
    67662003..67682902
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038492634.1XP_038348562.1  S-adenosylmethionine decarboxylase proenzyme isoform X1

    Conserved Domains (1) summary
    pfam01536
    Location:4325
    SAM_decarbox; Adenosylmethionine decarboxylase
  2. XM_038492636.1XP_038348564.1  S-adenosylmethionine decarboxylase proenzyme isoform X2

    Conserved Domains (1) summary
    pfam01536
    Location:1256
    SAM_decarbox; Adenosylmethionine decarboxylase
  3. XM_038492635.1XP_038348563.1  S-adenosylmethionine decarboxylase proenzyme isoform X2

    Conserved Domains (1) summary
    pfam01536
    Location:1256
    SAM_decarbox; Adenosylmethionine decarboxylase

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049753.1 Alternate UNSW_CanFamBas_1.0

    Range
    67507932..67528835
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038618822.1XP_038474750.1  S-adenosylmethionine decarboxylase proenzyme isoform X1

    Conserved Domains (1) summary
    pfam01536
    Location:4325
    SAM_decarbox; Adenosylmethionine decarboxylase
  2. XM_038618824.1XP_038474752.1  S-adenosylmethionine decarboxylase proenzyme isoform X2

    Conserved Domains (1) summary
    pfam01536
    Location:1256
    SAM_decarbox; Adenosylmethionine decarboxylase
  3. XM_038618823.1XP_038474751.1  S-adenosylmethionine decarboxylase proenzyme isoform X2

    Conserved Domains (1) summary
    pfam01536
    Location:1256
    SAM_decarbox; Adenosylmethionine decarboxylase

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049233.1 Alternate UU_Cfam_GSD_1.0

    Range
    67786118..67807019
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038554951.1XP_038410879.1  S-adenosylmethionine decarboxylase proenzyme isoform X1

    UniProtKB/TrEMBL
    A0A8C0L2E5, A0A8C0ME21
    Conserved Domains (1) summary
    pfam01536
    Location:4325
    SAM_decarbox; Adenosylmethionine decarboxylase
  2. XM_038554954.1XP_038410882.1  S-adenosylmethionine decarboxylase proenzyme isoform X2

    Conserved Domains (1) summary
    pfam01536
    Location:1256
    SAM_decarbox; Adenosylmethionine decarboxylase
  3. XM_038554952.1XP_038410880.1  S-adenosylmethionine decarboxylase proenzyme isoform X2

    Conserved Domains (1) summary
    pfam01536
    Location:1256
    SAM_decarbox; Adenosylmethionine decarboxylase

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006594.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    67251123..67272026
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005627711.4XP_005627768.2  S-adenosylmethionine decarboxylase proenzyme isoform X1

    UniProtKB/TrEMBL
    A0A8C0L2E5, A0A8C0ME21
    Conserved Domains (1) summary
    pfam01536
    Location:4325
    SAM_decarbox; Adenosylmethionine decarboxylase
  2. XM_022426451.2XP_022282159.1  S-adenosylmethionine decarboxylase proenzyme isoform X2

    Conserved Domains (1) summary
    pfam01536
    Location:1256
    SAM_decarbox; Adenosylmethionine decarboxylase
  3. XM_005627712.4XP_005627769.1  S-adenosylmethionine decarboxylase proenzyme isoform X2

    See identical proteins and their annotated locations for XP_005627769.1

    Conserved Domains (1) summary
    pfam01536
    Location:1256
    SAM_decarbox; Adenosylmethionine decarboxylase