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AIFM2 apoptosis inducing factor mitochondria associated 2 [ Canis lupus familiaris (dog) ]

Gene ID: 479236, updated on 5-Mar-2024

Summary

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Official Symbol
AIFM2provided by VGNC
Official Full Name
apoptosis inducing factor mitochondria associated 2provided by VGNC
Primary source
VGNC:VGNC:37738
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 4
Exon count:
12
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 4 NC_051808.1 (21362486..21379970, complement)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 4 NC_006586.4 (21219576..21236813, complement)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 4 NC_049225.1 (21816121..21833576, complement)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 4 NC_049264.1 (21260186..21277608, complement)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 4 NC_049745.1 (21465343..21482591, complement)

Chromosome 4 - NC_051808.1Genomic Context describing neighboring genes Neighboring gene collagen type XIII alpha 1 chain Neighboring gene uncharacterized LOC102157087 Neighboring gene uncharacterized LOC119873933 Neighboring gene macroH2A.2 histone Neighboring gene trypsin like peroxisomal matrix peptidase 1 Neighboring gene secretion associated Ras related GTPase 1A

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables electron-transferring-flavoprotein dehydrogenase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables flavin adenine dinucleotide binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in apoptotic mitochondrial changes IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of apoptotic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
apoptosis-inducing factor 2; ferroptosis suppressor protein 1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051808.1 Reference ROS_Cfam_1.0

    Range
    21362486..21379970 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038662813.1 → XP_038518741.1  ferroptosis suppressor protein 1 isoform X2

    Conserved Domains (1) summary
    cl39093
    Location:39 → 323
    Pyr_redox_2; Pyridine nucleotide-disulphide oxidoreductase

  2. XM_038662812.1 → XP_038518740.1  ferroptosis suppressor protein 1 isoform X1

    Conserved Domains (1) summary
    cl39093
    Location:39 → 356
    Pyr_redox_2; Pyridine nucleotide-disulphide oxidoreductase

  3. XM_038662808.1 → XP_038518736.1  ferroptosis suppressor protein 1 isoform X3

    Conserved Domains (1) summary
    cl39093
    Location:39 → 323
    Pyr_redox_2; Pyridine nucleotide-disulphide oxidoreductase

  4. XM_038662807.1 → XP_038518735.1  ferroptosis suppressor protein 1 isoform X3

    Conserved Domains (1) summary
    cl39093
    Location:39 → 323
    Pyr_redox_2; Pyridine nucleotide-disulphide oxidoreductase

  5. XM_038662809.1 → XP_038518737.1  ferroptosis suppressor protein 1 isoform X3

    Conserved Domains (1) summary
    cl39093
    Location:39 → 323
    Pyr_redox_2; Pyridine nucleotide-disulphide oxidoreductase

  6. XM_038662810.1 → XP_038518738.1  ferroptosis suppressor protein 1 isoform X3

    Conserved Domains (1) summary
    cl39093
    Location:39 → 323
    Pyr_redox_2; Pyridine nucleotide-disulphide oxidoreductase

  7. XM_038662811.1 → XP_038518739.1  ferroptosis suppressor protein 1 isoform X1

    Conserved Domains (1) summary
    cl39093
    Location:39 → 356
    Pyr_redox_2; Pyridine nucleotide-disulphide oxidoreductase

RNA

  1. XR_005425535.1 RNA Sequence

  2. XR_005425533.1 RNA Sequence

  3. XR_005425534.1 RNA Sequence

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049264.1 Alternate UMICH_Zoey_3.1

    Range
    21260186..21277608 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038473141.1 → XP_038329069.1  ferroptosis suppressor protein 1 isoform X2

    Conserved Domains (1) summary
    cl39093
    Location:39 → 323
    Pyr_redox_2; Pyridine nucleotide-disulphide oxidoreductase

  2. XM_038473140.1 → XP_038329068.1  ferroptosis suppressor protein 1 isoform X1

    Conserved Domains (1) summary
    cl39093
    Location:39 → 356
    Pyr_redox_2; Pyridine nucleotide-disulphide oxidoreductase

  3. XM_038473143.1 → XP_038329071.1  ferroptosis suppressor protein 1 isoform X3

    Conserved Domains (1) summary
    cl39093
    Location:39 → 323
    Pyr_redox_2; Pyridine nucleotide-disulphide oxidoreductase

  4. XM_038473142.1 → XP_038329070.1  ferroptosis suppressor protein 1 isoform X3

    Conserved Domains (1) summary
    cl39093
    Location:39 → 323
    Pyr_redox_2; Pyridine nucleotide-disulphide oxidoreductase

  5. XM_038473144.1 → XP_038329072.1  ferroptosis suppressor protein 1 isoform X3

    Conserved Domains (1) summary
    cl39093
    Location:39 → 323
    Pyr_redox_2; Pyridine nucleotide-disulphide oxidoreductase

  6. XM_038473145.1 → XP_038329073.1  ferroptosis suppressor protein 1 isoform X3

    Conserved Domains (1) summary
    cl39093
    Location:39 → 323
    Pyr_redox_2; Pyridine nucleotide-disulphide oxidoreductase

  7. XM_038473139.1 → XP_038329067.1  ferroptosis suppressor protein 1 isoform X1

    Conserved Domains (1) summary
    cl39093
    Location:39 → 356
    Pyr_redox_2; Pyridine nucleotide-disulphide oxidoreductase

RNA

  1. XR_005324119.1 RNA Sequence

  2. XR_005324117.1 RNA Sequence

  3. XR_005324118.1 RNA Sequence

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049745.1 Alternate UNSW_CanFamBas_1.0

    Range
    21465343..21482591 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038598505.1 → XP_038454433.1  ferroptosis suppressor protein 1 isoform X2

  2. XM_038598504.1 → XP_038454432.1  ferroptosis suppressor protein 1 isoform X1

  3. XM_038598503.1 → XP_038454431.1  ferroptosis suppressor protein 1 isoform X1

  4. XM_038598507.1 → XP_038454435.1  ferroptosis suppressor protein 1 isoform X3

  5. XM_038598506.1 → XP_038454434.1  ferroptosis suppressor protein 1 isoform X3

  6. XM_038598508.1 → XP_038454436.1  ferroptosis suppressor protein 1 isoform X3

  7. XM_038598509.1 → XP_038454437.1  ferroptosis suppressor protein 1 isoform X3

RNA

  1. XR_005392438.1 RNA Sequence

  2. XR_005392436.1 RNA Sequence

  3. XR_005392437.1 RNA Sequence

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049225.1 Alternate UU_Cfam_GSD_1.0

    Range
    21816121..21833576 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038534191.1 → XP_038390119.1  ferroptosis suppressor protein 1 isoform X2

    Conserved Domains (1) summary
    cl39093
    Location:39 → 323
    Pyr_redox_2; Pyridine nucleotide-disulphide oxidoreductase

  2. XM_038534190.1 → XP_038390118.1  ferroptosis suppressor protein 1 isoform X1

    Conserved Domains (1) summary
    cl39093
    Location:39 → 356
    Pyr_redox_2; Pyridine nucleotide-disulphide oxidoreductase

  3. XM_038534189.1 → XP_038390117.1  ferroptosis suppressor protein 1 isoform X1

    Conserved Domains (1) summary
    cl39093
    Location:39 → 356
    Pyr_redox_2; Pyridine nucleotide-disulphide oxidoreductase

  4. XM_038534193.1 → XP_038390121.1  ferroptosis suppressor protein 1 isoform X3

    Conserved Domains (1) summary
    cl39093
    Location:39 → 323
    Pyr_redox_2; Pyridine nucleotide-disulphide oxidoreductase

  5. XM_038534192.1 → XP_038390120.1  ferroptosis suppressor protein 1 isoform X3

    Conserved Domains (1) summary
    cl39093
    Location:39 → 323
    Pyr_redox_2; Pyridine nucleotide-disulphide oxidoreductase

  6. XM_038534194.1 → XP_038390122.1  ferroptosis suppressor protein 1 isoform X3

    Conserved Domains (1) summary
    cl39093
    Location:39 → 323
    Pyr_redox_2; Pyridine nucleotide-disulphide oxidoreductase

  7. XM_038534195.1 → XP_038390123.1  ferroptosis suppressor protein 1 isoform X3

    Conserved Domains (1) summary
    cl39093
    Location:39 → 323
    Pyr_redox_2; Pyridine nucleotide-disulphide oxidoreductase

RNA

  1. XR_005357926.1 RNA Sequence

  2. XR_005357924.1 RNA Sequence

  3. XR_005357925.1 RNA Sequence

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006586.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    21219576..21236813 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_022417525.1 → XP_022273233.1  ferroptosis suppressor protein 1 isoform X2

    Conserved Domains (1) summary
    cl26176
    Location:39 → 323
    NirB; NAD(P)H-nitrite reductase, large subunit [Energy production and conversion]

  2. XM_022417524.1 → XP_022273232.1  ferroptosis suppressor protein 1 isoform X1

    UniProtKB/TrEMBL
    A0A8C0LPQ2, A0A8P0SIE7
    Conserved Domains (1) summary
    cl26176
    Location:39 → 356
    NirB; NAD(P)H-nitrite reductase, large subunit [Energy production and conversion]

  3. XM_005618972.3 → XP_005619029.1  ferroptosis suppressor protein 1 isoform X3

    See identical proteins and their annotated locations for XP_005619029.1

    Conserved Domains (1) summary
    cl39093
    Location:39 → 323
    Pyr_redox_2; Pyridine nucleotide-disulphide oxidoreductase

  4. XM_005618971.4 → XP_005619028.1  ferroptosis suppressor protein 1 isoform X3

    See identical proteins and their annotated locations for XP_005619028.1

    Conserved Domains (1) summary
    cl39093
    Location:39 → 323
    Pyr_redox_2; Pyridine nucleotide-disulphide oxidoreductase

  5. XM_005618973.4 → XP_005619030.1  ferroptosis suppressor protein 1 isoform X3

    See identical proteins and their annotated locations for XP_005619030.1

    Conserved Domains (1) summary
    cl39093
    Location:39 → 323
    Pyr_redox_2; Pyridine nucleotide-disulphide oxidoreductase

  6. XM_005618976.4 → XP_005619033.1  ferroptosis suppressor protein 1 isoform X3

    See identical proteins and their annotated locations for XP_005619033.1

    Conserved Domains (1) summary
    cl39093
    Location:39 → 323
    Pyr_redox_2; Pyridine nucleotide-disulphide oxidoreductase

  7. XM_022417523.2 → XP_022273231.1  ferroptosis suppressor protein 1 isoform X1

    UniProtKB/TrEMBL
    A0A8C0LPQ2, A0A8P0SIE7
    Conserved Domains (1) summary
    cl26176
    Location:39 → 356
    NirB; NAD(P)H-nitrite reductase, large subunit [Energy production and conversion]

RNA

  1. XR_002625677.1 RNA Sequence

  2. XR_002625675.1 RNA Sequence

  3. XR_002625676.2 RNA Sequence

Nucleotide Protein
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