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ACVR2A activin A receptor type 2A [ Canis lupus familiaris (dog) ]

Gene ID: 476140, updated on 5-Mar-2024

Summary

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Official Symbol
ACVR2Aprovided by VGNC
Official Full Name
activin A receptor type 2Aprovided by VGNC
Primary source
VGNC:VGNC:37564
See related
Ensembl:ENSCAFG00845006266
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 19
Exon count:
12
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 19 NC_051823.1 (51114507..51199229)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 19 NC_006601.4 (49765961..49850433)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 19 NC_049240.1 (51291788..51376557)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 19 NC_049279.1 (49760723..49845201)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 19 NC_049760.1 (49894649..49979187)

Chromosome 19 - NC_051823.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC111091197 Neighboring gene 60S ribosomal protein L26-like Neighboring gene phosphate carrier protein, mitochondrial-like Neighboring gene origin recognition complex subunit 4 Neighboring gene uncharacterized LOC119864497

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables activin binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables activin receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in activin receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cellular response to growth factor stimulus IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of activin receptor complex IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
activin receptor type-2A
XP_038282146.1
XP_038282147.1
XP_038310617.1
XP_038358340.1
XP_038358341.1
XP_038421063.1
XP_038421064.1
XP_038485161.1
XP_038485163.1
XP_857260.1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051823.1 Reference ROS_Cfam_1.0

    Range
    51114507..51199229
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038426218.1 → XP_038282146.1  activin receptor type-2A isoform X1

    UniProtKB/TrEMBL
    A0A8C0R225, A0A8C0Z3E6, A0A8I3MYH0
    Related
    ENSCAFP00845008741.1, ENSCAFT00845011205.1
    Conserved Domains (2) summary
    cd14141
    Location:196 → 485
    STKc_ACVR2a; Catalytic domain of the Serine/Threonine Kinase, Activin Type IIA Receptor
    pfam01064
    Location:59 → 111
    Activin_recp; Activin types I and II receptor domain

  2. XM_038426219.1 → XP_038282147.1  activin receptor type-2A isoform X2

    Conserved Domains (1) summary
    cd14141
    Location:88 → 377
    STKc_ACVR2a; Catalytic domain of the Serine/Threonine Kinase, Activin Type IIA Receptor

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049279.1 Alternate UMICH_Zoey_3.1

    Range
    49760723..49845201
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038502412.1 → XP_038358340.1  activin receptor type-2A isoform X1

    Conserved Domains (2) summary
    cd14141
    Location:196 → 485
    STKc_ACVR2a; Catalytic domain of the Serine/Threonine Kinase, Activin Type IIA Receptor
    pfam01064
    Location:59 → 111
    Activin_recp; Activin types I and II receptor domain

  2. XM_038502413.1 → XP_038358341.1  activin receptor type-2A isoform X2

    Conserved Domains (1) summary
    cd14141
    Location:88 → 377
    STKc_ACVR2a; Catalytic domain of the Serine/Threonine Kinase, Activin Type IIA Receptor

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049760.1 Alternate UNSW_CanFamBas_1.0

    Range
    49894649..49979187
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038629233.1 → XP_038485161.1  activin receptor type-2A isoform X1

    Conserved Domains (2) summary
    cd14141
    Location:196 → 485
    STKc_ACVR2a; Catalytic domain of the Serine/Threonine Kinase, Activin Type IIA Receptor
    pfam01064
    Location:59 → 111
    Activin_recp; Activin types I and II receptor domain

  2. XM_038629235.1 → XP_038485163.1  activin receptor type-2A isoform X2

    Conserved Domains (1) summary
    cd14141
    Location:88 → 377
    STKc_ACVR2a; Catalytic domain of the Serine/Threonine Kinase, Activin Type IIA Receptor

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049240.1 Alternate UU_Cfam_GSD_1.0

    Range
    51291788..51376557
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038565135.1 → XP_038421063.1  activin receptor type-2A isoform X1

    UniProtKB/TrEMBL
    A0A8C0R225, A0A8C0Z3E6, A0A8I3MYH0
    Conserved Domains (2) summary
    cd14141
    Location:196 → 485
    STKc_ACVR2a; Catalytic domain of the Serine/Threonine Kinase, Activin Type IIA Receptor
    pfam01064
    Location:59 → 111
    Activin_recp; Activin types I and II receptor domain

  2. XM_038565136.1 → XP_038421064.1  activin receptor type-2A isoform X2

    Conserved Domains (1) summary
    cd14141
    Location:88 → 377
    STKc_ACVR2a; Catalytic domain of the Serine/Threonine Kinase, Activin Type IIA Receptor

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006601.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    49765961..49850433
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_852167.6 → XP_857260.1  activin receptor type-2A isoform X1

    See identical proteins and their annotated locations for XP_857260.1

    UniProtKB/TrEMBL
    A0A8C0R225, A0A8C0Z3E6, A0A8I3MYH0
    Conserved Domains (2) summary
    cd14141
    Location:196 → 485
    STKc_ACVR2a; Catalytic domain of the Serine/Threonine Kinase, Activin Type IIA Receptor
    pfam01064
    Location:59 → 111
    Activin_recp; Activin types I and II receptor domain

  2. XM_038454689.1 → XP_038310617.1  activin receptor type-2A isoform X2

    Conserved Domains (1) summary
    cd14141
    Location:88 → 377
    STKc_ACVR2a; Catalytic domain of the Serine/Threonine Kinase, Activin Type IIA Receptor
Nucleotide Protein
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