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AFF4 ALF transcription elongation factor 4 [ Canis lupus familiaris (dog) ]

Gene ID: 474678, updated on 5-Mar-2024

Summary

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Official Symbol
AFF4provided by VGNC
Official Full Name
ALF transcription elongation factor 4provided by VGNC
Primary source
VGNC:VGNC:37688
See related
Ensembl:ENSCAFG00845011722
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 11
Exon count:
22
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 11 NC_051815.1 (21945075..22033184, complement)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 11 NC_006593.4 (19960642..20053417, complement)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 11 NC_049232.1 (21153663..21241674, complement)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 11 NC_049271.1 (20663430..20751443, complement)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 11 NC_049752.1 (20511144..20599256, complement)

Chromosome 11 - NC_051815.1Genomic Context describing neighboring genes Neighboring gene ubiquinol-cytochrome c reductase complex III subunit VII Neighboring gene liver enriched antimicrobial peptide 2 Neighboring gene uncharacterized LOC111098022 Neighboring gene zinc finger CCHC-type containing 10 Neighboring gene U4 spliceosomal RNA Neighboring gene heat shock protein family A (Hsp70) member 4

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Process Evidence Code Pubs
involved_in regulation of gene expression IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of super elongation complex IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
AF4/FMR2 family member 4

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051815.1 Reference ROS_Cfam_1.0

    Range
    21945075..22033184 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038681504.1 → XP_038537432.1  AF4/FMR2 family member 4 isoform X2

    UniProtKB/TrEMBL
    A0A8C0JJ70, A0A8C0RZP2
    Conserved Domains (2) summary
    pfam05110
    Location:2 → 450
    AF-4; AF-4 proto-oncoprotein
    pfam18876
    Location:870 → 1133
    AF-4_C; AF-4 proto-oncoprotein C-terminal region

  2. XM_038681503.1 → XP_038537431.1  AF4/FMR2 family member 4 isoform X1

    UniProtKB/TrEMBL
    A0A8C0JJ70, A0A8C0QAS7, A0A8I3NGB0
    Related
    ENSCAFP00845016341.1, ENSCAFT00845020819.1
    Conserved Domains (2) summary
    pfam05110
    Location:2 → 479
    AF-4; AF-4 proto-oncoprotein
    pfam18876
    Location:899 → 1162
    AF-4_C; AF-4 proto-oncoprotein C-terminal region

  3. XM_038681502.1 → XP_038537430.1  AF4/FMR2 family member 4 isoform X1

    UniProtKB/TrEMBL
    A0A8C0JJ70, A0A8C0QAS7, A0A8I3NGB0
    Conserved Domains (2) summary
    pfam05110
    Location:2 → 479
    AF-4; AF-4 proto-oncoprotein
    pfam18876
    Location:899 → 1162
    AF-4_C; AF-4 proto-oncoprotein C-terminal region

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049271.1 Alternate UMICH_Zoey_3.1

    Range
    20663430..20751443 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038490068.1 → XP_038345996.1  AF4/FMR2 family member 4 isoform X2

    Conserved Domains (2) summary
    pfam05110
    Location:2 → 450
    AF-4; AF-4 proto-oncoprotein
    pfam18876
    Location:870 → 1133
    AF-4_C; AF-4 proto-oncoprotein C-terminal region

  2. XM_038490067.1 → XP_038345995.1  AF4/FMR2 family member 4 isoform X1

    Conserved Domains (2) summary
    pfam05110
    Location:2 → 479
    AF-4; AF-4 proto-oncoprotein
    pfam18876
    Location:899 → 1162
    AF-4_C; AF-4 proto-oncoprotein C-terminal region

  3. XM_038490066.1 → XP_038345994.1  AF4/FMR2 family member 4 isoform X1

    Conserved Domains (2) summary
    pfam05110
    Location:2 → 479
    AF-4; AF-4 proto-oncoprotein
    pfam18876
    Location:899 → 1162
    AF-4_C; AF-4 proto-oncoprotein C-terminal region

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049752.1 Alternate UNSW_CanFamBas_1.0

    Range
    20511144..20599256 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038616009.1 → XP_038471937.1  AF4/FMR2 family member 4 isoform X2

    Conserved Domains (2) summary
    pfam05110
    Location:2 → 450
    AF-4; AF-4 proto-oncoprotein
    pfam18876
    Location:870 → 1133
    AF-4_C; AF-4 proto-oncoprotein C-terminal region

  2. XM_038616008.1 → XP_038471936.1  AF4/FMR2 family member 4 isoform X1

    Conserved Domains (2) summary
    pfam05110
    Location:2 → 479
    AF-4; AF-4 proto-oncoprotein
    pfam18876
    Location:899 → 1162
    AF-4_C; AF-4 proto-oncoprotein C-terminal region

  3. XM_038616007.1 → XP_038471935.1  AF4/FMR2 family member 4 isoform X1

    Conserved Domains (2) summary
    pfam05110
    Location:2 → 479
    AF-4; AF-4 proto-oncoprotein
    pfam18876
    Location:899 → 1162
    AF-4_C; AF-4 proto-oncoprotein C-terminal region

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049232.1 Alternate UU_Cfam_GSD_1.0

    Range
    21153663..21241674 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038552148.1 → XP_038408076.1  AF4/FMR2 family member 4 isoform X2

    UniProtKB/TrEMBL
    A0A8C0JJ70, A0A8C0RZP2
    Conserved Domains (2) summary
    pfam05110
    Location:2 → 450
    AF-4; AF-4 proto-oncoprotein
    pfam18876
    Location:870 → 1133
    AF-4_C; AF-4 proto-oncoprotein C-terminal region

  2. XM_038552147.1 → XP_038408075.1  AF4/FMR2 family member 4 isoform X1

    UniProtKB/TrEMBL
    A0A8C0JJ70, A0A8C0QAS7, A0A8I3NGB0
    Conserved Domains (2) summary
    pfam05110
    Location:2 → 479
    AF-4; AF-4 proto-oncoprotein
    pfam18876
    Location:899 → 1162
    AF-4_C; AF-4 proto-oncoprotein C-terminal region

  3. XM_038552146.1 → XP_038408074.1  AF4/FMR2 family member 4 isoform X1

    UniProtKB/TrEMBL
    A0A8C0JJ70, A0A8C0QAS7, A0A8I3NGB0
    Conserved Domains (2) summary
    pfam05110
    Location:2 → 479
    AF-4; AF-4 proto-oncoprotein
    pfam18876
    Location:899 → 1162
    AF-4_C; AF-4 proto-oncoprotein C-terminal region

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006593.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    19960642..20053417 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038669281.1 → XP_038525209.1  AF4/FMR2 family member 4 isoform X2

    UniProtKB/TrEMBL
    A0A8C0JJ70, A0A8C0RZP2
    Conserved Domains (2) summary
    pfam05110
    Location:2 → 450
    AF-4; AF-4 proto-oncoprotein
    pfam18876
    Location:870 → 1133
    AF-4_C; AF-4 proto-oncoprotein C-terminal region

  2. XM_038669272.1 → XP_038525200.1  AF4/FMR2 family member 4 isoform X1

    UniProtKB/TrEMBL
    A0A8C0JJ70, A0A8C0QAS7, A0A8I3NGB0
    Conserved Domains (2) summary
    pfam05110
    Location:2 → 479
    AF-4; AF-4 proto-oncoprotein
    pfam18876
    Location:899 → 1162
    AF-4_C; AF-4 proto-oncoprotein C-terminal region

  3. XM_038669263.1 → XP_038525191.1  AF4/FMR2 family member 4 isoform X1

    UniProtKB/TrEMBL
    A0A8C0JJ70, A0A8C0QAS7, A0A8I3NGB0
    Conserved Domains (2) summary
    pfam05110
    Location:2 → 479
    AF-4; AF-4 proto-oncoprotein
    pfam18876
    Location:899 → 1162
    AF-4_C; AF-4 proto-oncoprotein C-terminal region
Nucleotide Protein
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