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capza1b capping actin protein of muscle Z-line subunit alpha 1b [ Danio rerio (zebrafish) ]

Gene ID: 474327, updated on 11-Apr-2024

Summary

Official Symbol
capza1bprovided by ZNC
Official Full Name
capping actin protein of muscle Z-line subunit alpha 1bprovided by ZNC
Primary source
ZFIN:ZDB-GENE-031002-24
See related
Ensembl:ENSDARG00000056090 AllianceGenome:ZFIN:ZDB-GENE-031002-24
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
sb:cb852; zK16K6.1; wu:fb36c09; wu:fc85a01; wu:fj45f05; zgc:101755; si:dkey-16k6.1
Summary
Predicted to enable actin filament binding activity. Predicted to be involved in actin cytoskeleton organization and barbed-end actin filament capping. Predicted to act upstream of or within actin filament capping. Predicted to be part of F-actin capping protein complex. Is expressed in adaxial cell; myotome; and somite. Orthologous to human CAPZA1 (capping actin protein of muscle Z-line subunit alpha 1). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
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Genomic context

See capza1b in Genome Data Viewer
Location:
chromosome: 8
Exon count:
10
Annotation release Status Assembly Chr Location
106 current GRCz11 (GCF_000002035.6) 8 NC_007119.7 (27807974..27817489)
105 previous assembly GRCz10 (GCF_000002035.5) 8 NC_007119.6 (27788835..27798350)

Chromosome 8 - NC_007119.7Genomic Context describing neighboring genes Neighboring gene Mov10 RNA helicase b, tandem duplicate 1 Neighboring gene wingless-type MMTV integration site family, member 2Bb Neighboring gene CTTNBP2 N-terminal like b Neighboring gene potassium voltage-gated channel, Shal-related subfamily, member 3

Genomic regions, transcripts, and products

Expression

  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

General gene information

Markers

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables actin binding IEA
Inferred from Electronic Annotation
more info
 
enables actin filament binding IBA
Inferred from Biological aspect of Ancestor
more info
 
Process Evidence Code Pubs
involved_in actin cytoskeleton organization IBA
Inferred from Biological aspect of Ancestor
more info
 
acts_upstream_of_or_within actin filament capping IEA
Inferred from Electronic Annotation
more info
 
involved_in barbed-end actin filament capping IBA
Inferred from Biological aspect of Ancestor
more info
 
acts_upstream_of_or_within barbed-end actin filament capping IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
part_of F-actin capping protein complex IBA
Inferred from Biological aspect of Ancestor
more info
 
part_of F-actin capping protein complex IEA
Inferred from Electronic Annotation
more info
 
is_active_in cortical cytoskeleton IBA
Inferred from Biological aspect of Ancestor
more info
 

General protein information

Preferred Names
F-actin-capping protein subunit alpha-1b
Names
F-actin capping protein alpha-1 subunit
capping protein (actin filament) muscle Z-line, alpha 1b
scapping protein (actin filament) muscle Z-line, alpha 1b

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001006663.1NP_001006664.1  F-actin-capping protein subunit alpha-1b

    See identical proteins and their annotated locations for NP_001006664.1

    Status: VALIDATED

    Source sequence(s)
    AL845328, BC083268, CN841765
    UniProtKB/TrEMBL
    B5DDC0, F6PDN8, Q5XJN1, Q6ZM50
    Related
    ENSDARP00000072971.5, ENSDART00000078509.6
    Conserved Domains (1) summary
    pfam01267
    Location:14282
    F-actin_cap_A; F-actin capping protein alpha subunit

RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007119.7 Reference GRCz11 Primary Assembly

    Range
    27807974..27817489
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Reference GRCz11 ALT_DRER_TU_1

Genomic

  1. NW_018394727.1 Reference GRCz11 ALT_DRER_TU_1

    Range
    776976..786440
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Reference GRCz11 ALT_DRER_TU_2

Genomic

  1. NW_018395273.1 Reference GRCz11 ALT_DRER_TU_2

    Range
    1087..6184
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)