ANAPC4 anaphase promoting complex subunit 4 [Pan troglodytes (chimpanzee)] - Gene

Summary

Official Symbol: ANAPC4provided by VGNC
Official Full Name: anaphase promoting complex subunit 4provided by VGNC
Primary source: VGNC:VGNC:556
Locus tag: CK820_G0007590
See related: Ensembl:ENSPTRG00000015963
Gene type: protein coding
RefSeq status: MODEL
Organism: Pan troglodytes
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 4

Exon count:: 29

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2)	3	NC_072401.2 (25842627..25882421)
RS_2023_04	previous assembly	NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1)	4	NC_072402.1 (25842710..25882402)

Chromosome 3 - NC_072401.2 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

SHGC-50273 (e-PCR)
- UniSTS:76601

SHGC-24100 (e-PCR)
- UniSTS:76602

SHGC-154840 (e-PCR)
- UniSTS:183887

RH92873 (e-PCR)
- UniSTS:92001

D4S2517E (e-PCR)
- UniSTS:39789

SHGC-59815 (e-PCR)
- UniSTS:78219

ANAPC4 (e-PCR)
- UniSTS:503504

Homology

NCBI Orthologs

Orthologs from OrthoDB

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables protein binding	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in anaphase-promoting complex-dependent catabolic process	IEA Inferred from Electronic Annotation more info	PubMed
involved_in protein K11-linked ubiquitination	IEA Inferred from Electronic Annotation more info	PubMed
involved_in regulation of mitotic metaphase/anaphase transition	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
part_of anaphase-promoting complex	IEA Inferred from Electronic Annotation more info	PubMed
located_in nuclear periphery	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: anaphase-promoting complex subunit 4

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Genomic

NC_072401.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Range

25842627..25882421

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_001165393.5 → XP_001165393.1 anaphase-promoting complex subunit 4 isoform X2

See identical proteins and their annotated locations for XP_001165393.1

UniProtKB/TrEMBL

A0A2I3SB37, A0A2J8NW00, A0A8I3B2D2, K7BPW2, K7BWJ2

Conserved Domains (3) summary

sd00039
Location:24 → 59

7WD40; WD40 repeat [structural motif]

pfam12894
Location:26 → 118

ANAPC4_WD40; Anaphase-promoting complex subunit 4 WD40 domain

pfam12896
Location:232 → 431

ANAPC4; Anaphase-promoting complex, cyclosome, subunit 4
XM_009447445.4 → XP_009445720.1 anaphase-promoting complex subunit 4 isoform X1

See identical proteins and their annotated locations for XP_009445720.1

UniProtKB/TrEMBL

A0A2I3SB37, A0A2J8NVY7, A0A6D2XUF8, H2QPA9

Related

ENSPTRP00000027484.3

Conserved Domains (3) summary

sd00039
Location:24 → 59

7WD40; WD40 repeat [structural motif]

pfam12894
Location:26 → 118

ANAPC4_WD40; Anaphase-promoting complex subunit 4 WD40 domain

pfam12896
Location:232 → 431

ANAPC4; Anaphase-promoting complex, cyclosome, subunit 4
XM_054682813.2 → XP_054538788.1 anaphase-promoting complex subunit 4 isoform X3
XM_063809436.1 → XP_063665506.1 anaphase-promoting complex subunit 4 isoform X4
XM_009447446.4 → XP_009445721.1 anaphase-promoting complex subunit 4 isoform X5

UniProtKB/TrEMBL

A0A2I3SB37

Conserved Domains (1) summary

pfam12896
Location:120 → 319

ANAPC4; Anaphase-promoting complex, cyclosome, subunit 4
XM_063809437.1 → XP_063665507.1 anaphase-promoting complex subunit 4 isoform X6