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ADAMTS4 ADAM metallopeptidase with thrombospondin type 1 motif 4 [ Pan troglodytes (chimpanzee) ]

Gene ID: 457453, updated on 29-Mar-2024

Summary

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Official Symbol
ADAMTS4provided by VGNC
Official Full Name
ADAM metallopeptidase with thrombospondin type 1 motif 4provided by VGNC
Primary source
VGNC:VGNC:44
Locus tag
CK820_G0049345
See related
Ensembl:ENSPTRG00000001576
Gene type
protein coding
RefSeq status
MODEL
Organism
Pan troglodytes
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 1
Exon count:
9
Annotation release Status Assembly Chr Location
RS_2024_02 current NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2) 1 NC_072398.2 (88020040..88029327)
RS_2023_04 previous assembly NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1) 1 NC_072398.1 (143320405..143329872, complement)

Chromosome 1 - NC_072398.2Genomic Context describing neighboring genes Neighboring gene apolipoprotein A2 Neighboring gene Fc epsilon receptor Ig Neighboring gene NADH:ubiquinone oxidoreductase core subunit S2 Neighboring gene beta-1,4-galactosyltransferase 3 Neighboring gene protoporphyrinogen oxidase Neighboring gene ubiquitin specific peptidase 21

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables metalloendopeptidase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in extracellular matrix organization IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in proteolysis IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in extracellular matrix IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
A disintegrin and metalloproteinase with thrombospondin motifs 4
XP_016786405.1
XP_513940.2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Genomic

  1. NC_072398.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

    Range
    88020040..88029327
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_513940.6 → XP_513940.2  A disintegrin and metalloproteinase with thrombospondin motifs 4 isoform X1

    See identical proteins and their annotated locations for XP_513940.2

    UniProtKB/TrEMBL
    A0A2I3T896, A0A2J8JAQ3, A0A6D2X7D0, H2R0A6
    Related
    ENSPTRP00000085442.1
    Conserved Domains (5) summary
    smart00209
    Location:531 → 575
    TSP1; Thrombospondin type 1 repeats
    cd04273
    Location:218 → 425
    ZnMc_ADAMTS_like; Zinc-dependent metalloprotease, ADAMTS_like subgroup. ADAMs (A Disintegrin And Metalloprotease) are glycoproteins, which play roles in cell signaling, cell fusion, and cell-cell interactions. This particular subfamily represents domain architectures that ...
    pfam01562
    Location:60 → 181
    Pep_M12B_propep; Reprolysin family propeptide
    pfam05986
    Location:687 → 802
    ADAM_spacer1; ADAM-TS Spacer 1
    cl15456
    Location:438 → 509
    ADAM_CR; ADAM cysteine-rich

  2. XM_016930916.3 → XP_016786405.1  A disintegrin and metalloproteinase with thrombospondin motifs 4 isoform X2

    UniProtKB/TrEMBL
    H2R0A6
    Conserved Domains (4) summary
    smart00209
    Location:531 → 575
    TSP1; Thrombospondin type 1 repeats
    cd04273
    Location:218 → 425
    ZnMc_ADAMTS_like; Zinc-dependent metalloprotease, ADAMTS_like subgroup. ADAMs (A Disintegrin And Metalloprotease) are glycoproteins, which play roles in cell signaling, cell fusion, and cell-cell interactions. This particular subfamily represents domain architectures that ...
    pfam01562
    Location:60 → 181
    Pep_M12B_propep; Reprolysin family propeptide
    cl15456
    Location:438 → 509
    ADAM_CR; ADAM cysteine-rich
Nucleotide Protein
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