ADCY4 adenylate cyclase 4 [Pan troglodytes (chimpanzee)] - Gene

Summary

Official Symbol: ADCY4provided by VGNC
Official Full Name: adenylate cyclase 4provided by VGNC
Primary source: VGNC:VGNC:3507
See related: Ensembl:ENSPTRG00000006216
Gene type: protein coding
RefSeq status: MODEL
Organism: Pan troglodytes
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 14

Exon count:: 26

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2)	15	NC_072413.2 (22614351..22631030, complement)
RS_2023_04	previous assembly	NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1)	14	NC_072412.1 (15838036..15854776, complement)

Chromosome 15 - NC_072413.2 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Pathways from PubChem

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General gene information

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Markers

RH91896 (e-PCR)
- UniSTS:85933

RH93999 (e-PCR)
- UniSTS:85433

MARC_3911-3912:996679167:1 (e-PCR)
- UniSTS:269286

Homology

NCBI Orthologs

Orthologs from OrthoDB

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables adenylate cyclase activity	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in adenylate cyclase-activating G protein-coupled receptor signaling pathway	IEA Inferred from Electronic Annotation more info	PubMed
involved_in adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway	IEA Inferred from Electronic Annotation more info	PubMed
involved_in cAMP biosynthetic process	IEA Inferred from Electronic Annotation more info	PubMed
involved_in intracellular signal transduction	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in plasma membrane	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: adenylate cyclase type 4

XP_009425874.1

EC 4.6.1.1

XP_016781416.1

EC 4.6.1.1

XP_063649310.1

EC 4.6.1.1

XP_063649311.1

EC 4.6.1.1

XP_063649312.1

EC 4.6.1.1

XP_509874.2

EC 4.6.1.1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Genomic

NC_072413.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Range

22614351..22631030 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_063793240.1 → XP_063649310.1 adenylate cyclase type 4 isoform X1

UniProtKB/TrEMBL

H2Q832
XM_063793241.1 → XP_063649311.1 adenylate cyclase type 4 isoform X1

UniProtKB/TrEMBL

H2Q832
XM_063793242.1 → XP_063649312.1 adenylate cyclase type 4 isoform X4
XM_509874.7 → XP_509874.2 adenylate cyclase type 4 isoform X1

See identical proteins and their annotated locations for XP_509874.2

UniProtKB/TrEMBL

H2Q832

Conserved Domains (4) summary

smart00044
Location:219 → 422

CYCc; Adenylyl- / guanylyl cyclase, catalytic domain

pfam00211
Location:864 → 1063

Guanylate_cyc; Adenylate and Guanylate cyclase catalytic domain

pfam06327
Location:479 → 583

DUF1053; Domain of Unknown Function (DUF1053)

pfam16214
Location:115 → 246

AC_N; Adenylyl cyclase N-terminal extracellular and transmembrane region
XM_009427599.4 → XP_009425874.1 adenylate cyclase type 4 isoform X2

Conserved Domains (4) summary

smart00044
Location:219 → 422

CYCc; Adenylyl- / guanylyl cyclase, catalytic domain

pfam00211
Location:264 → 418

Guanylate_cyc; Adenylate and Guanylate cyclase catalytic domain

pfam06327
Location:479 → 583

DUF1053; Domain of Unknown Function (DUF1053)

pfam16214
Location:115 → 246

AC_N; Adenylyl cyclase N-terminal extracellular and transmembrane region
XM_016925927.3 → XP_016781416.1 adenylate cyclase type 4 isoform X3