naa50 N-alpha-acetyltransferase 50, NatE catalytic subunit [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: naa50provided by ZNC
Official Full Name: N-alpha-acetyltransferase 50, NatE catalytic subunitprovided by ZNC
Primary source: ZFIN:ZDB-GENE-040801-142
See related: Ensembl:ENSDARG00000027825 AllianceGenome:ZFIN:ZDB-GENE-040801-142
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: mak3; nat13; wu:fb01d06; wu:fe47h02; zgc:100949
Summary: Predicted to enable H4 histone acetyltransferase activity; peptide alpha-N-acetyltransferase activity; and peptidyl-lysine acetyltransferase activity. Acts upstream of or within somitogenesis. Predicted to be located in cytosol and nucleus. Predicted to be part of NatA complex. Predicted to be active in cytoplasm. Is expressed in blood vasculature; head; and myotome. Orthologous to human NAA50 (N-alpha-acetyltransferase 50, NatE catalytic subunit). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 24

Exon count:: 5

Annotation release	Status	Assembly	Chr	Location
106	current	GRCz11 (GCF_000002035.6)	24	NC_007135.7 (21174850..21183616)
105	previous assembly	GRCz10 (GCF_000002035.5)	24	NC_007135.6 (21030422..21039197)

Chromosome 24 - NC_007135.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

fb01d06.x1 (e-PCR)
- UniSTS:189784

fb01d06.x1 (e-PCR)
- UniSTS:189785

fe47h02.x1 (e-PCR)
- UniSTS:204385

Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables 2,6-dimethyl-5-methylene-3-oxo-heptanoyl-CoA C-acetyltransferase activity	IEA Inferred from Electronic Annotation more info
enables 2-methylhexanoyl-CoA C-acetyltransferase activity	IEA Inferred from Electronic Annotation more info
enables acyltransferase activity	IEA Inferred from Electronic Annotation more info
enables acyltransferase activity, transferring groups other than amino-acyl groups	IEA Inferred from Electronic Annotation more info
enables histone H4 acetyltransferase activity	ISS Inferred from Sequence or Structural Similarity more info
enables keto acid formate lyase activity	IEA Inferred from Electronic Annotation more info
enables peptide alpha-N-acetyltransferase activity	ISS Inferred from Sequence or Structural Similarity more info
enables peptidyl-lysine acetyltransferase activity	ISS Inferred from Sequence or Structural Similarity more info
enables transferase activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in establishment of mitotic sister chromatid cohesion	ISS Inferred from Sequence or Structural Similarity more info
involved_in mitotic sister chromatid cohesion	IBA Inferred from Biological aspect of Ancestor more info
involved_in mitotic sister chromatid cohesion, centromeric	ISS Inferred from Sequence or Structural Similarity more info
acts_upstream_of_or_within somitogenesis	IMP Inferred from Mutant Phenotype more info	PubMed

Component	Evidence Code	Pubs
part_of NatA complex	IBA Inferred from Biological aspect of Ancestor more info
located_in cytoplasm	IEA Inferred from Electronic Annotation more info
located_in cytoplasm	ISS Inferred from Sequence or Structural Similarity more info
located_in cytosol	ISS Inferred from Sequence or Structural Similarity more info
located_in nucleus	IEA Inferred from Electronic Annotation more info
located_in nucleus	ISS Inferred from Sequence or Structural Similarity more info

General protein information

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Preferred Names: N-alpha-acetyltransferase 50

Names: MAK31-like protein; Mak3 homolog; N-acetyltransferase 13; N-acetyltransferase NAT13; N-epsilon-acetyltransferase 50; natE catalytic subunit

NP_001003623.1

EC 2.3.1.258

XP_005162748.1

EC 2.3.1.258

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001003623.1 → NP_001003623.1 N-alpha-acetyltransferase 50

See identical proteins and their annotated locations for NP_001003623.1

Status: PROVISIONAL

Source sequence(s)

BC078316

UniProtKB/Swiss-Prot

Q6DBY2

Related

ENSDARP00000128410.1, ENSDART00000154940.3

Conserved Domains (1) summary

COG0456
Location:9 → 144

RimI; Ribosomal protein S18 acetylase RimI and related acetyltransferases [Translation, ribosomal structure and biogenesis]