dnajb1a DnaJ heat shock protein family (Hsp40) member B1a [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: dnajb1aprovided by ZNC
Official Full Name: DnaJ heat shock protein family (Hsp40) member B1aprovided by ZNC
Primary source: ZFIN:ZDB-GENE-040801-90
See related: Ensembl:ENSDARG00000099383 AllianceGenome:ZFIN:ZDB-GENE-040801-90
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: hspf1; dnajb1; zf-Hsp40; zgc:101068
Summary: Predicted to enable several functions, including Hsp70 protein binding activity; chaperone binding activity; and unfolded protein binding activity. Acts upstream of or within lens development in camera-type eye. Predicted to be active in cytosol. Orthologous to human DNAJB1 (DnaJ heat shock protein family (Hsp40) member B1). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs: all
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Genomic context

Location:: chromosome: 3

Exon count:: 3

Annotation release	Status	Assembly	Chr	Location
106	current	GRCz11 (GCF_000002035.6)	3	NC_007114.7 (49150822..49163648, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	3	NC_007114.6 (45005411..45018237, complement)

Chromosome 3 - NC_007114.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables Hsp70 protein binding	IBA Inferred from Biological aspect of Ancestor more info
enables transcription corepressor activity	IBA Inferred from Biological aspect of Ancestor more info
enables unfolded protein binding	IBA Inferred from Biological aspect of Ancestor more info
enables unfolded protein binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in chaperone cofactor-dependent protein refolding	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within lens development in camera-type eye	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in negative regulation of transcription by RNA polymerase II	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within protein folding	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
is_active_in cytosol	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: dnaJ homolog subfamily B member 1a

Names: DnaJ (Hsp40) homolog, subfamily B, member 1; DnaJ (Hsp40) homolog, subfamily B, member 1a; heat shock 40kD protein 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001003571.1 → NP_001003571.1 dnaJ homolog subfamily B member 1a

See identical proteins and their annotated locations for NP_001003571.1

Status: PROVISIONAL

Source sequence(s)

BC077119

UniProtKB/TrEMBL

Q6DEJ4

Related

ENSDARP00000141952.1, ENSDART00000166146.2

Conserved Domains (3) summary

cd10747
Location:157 → 321

DnaJ_C; C-terminal substrate binding domain of DnaJ and HSP40

COG0484
Location:1 → 335

DnaJ; DnaJ-class molecular chaperone with C-terminal Zn finger domain [Posttranslational modification, protein turnover, chaperones]

pfam00226
Location:4 → 65

DnaJ; DnaJ domain