sypb synaptophysin b [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: sypbprovided by ZNC
Official Full Name: synaptophysin bprovided by ZNC
Primary source: ZFIN:ZDB-GENE-040718-205
See related: Ensembl:ENSDARG00000002230 AllianceGenome:ZFIN:ZDB-GENE-040718-205
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: zgc:92837; zgc:136469
Summary: Acts upstream of or within glial cell development and retina development in camera-type eye. Predicted to be located in membrane; neuron projection; and synaptic vesicle. Predicted to be integral component of membrane. Predicted to be active in presynaptic active zone and synaptic vesicle membrane. Is expressed in central nervous system; lateral wall spinal cord; midbrain; retinal inner plexiform layer; and retinal outer plexiform layer. Human ortholog(s) of this gene implicated in non-syndromic X-linked intellectual disability 96. Orthologous to human SYP (synaptophysin). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs: all
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Genomic context

Location:: chromosome: 8

Exon count:: 8

Annotation release	Status	Assembly	Chr	Location
106	current	GRCz11 (GCF_000002035.6)	8	NC_007119.7 (49404076..49432010, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	8	NC_007119.6 (49415307..49443241, complement)

Chromosome 8 - NC_007119.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

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General gene information

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Gene Ontology Provided by ZFIN

Process	Evidence Code	Pubs
acts_upstream_of_or_within glial cell development	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within retina development in camera-type eye	IMP Inferred from Mutant Phenotype more info	PubMed

Component	Evidence Code	Pubs
located_in membrane	IEA Inferred from Electronic Annotation more info
is_active_in presynaptic active zone	IBA Inferred from Biological aspect of Ancestor more info
located_in synaptic vesicle	IEA Inferred from Electronic Annotation more info
is_active_in synaptic vesicle membrane	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: synaptophysin b

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.