ARHGEF10 Rho guanine nucleotide exchange factor 10 [Gallus gallus (chicken)] - Gene

Summary

Official Symbol: ARHGEF10provided by CGNC
Official Full Name: Rho guanine nucleotide exchange factor 10provided by CGNC
Primary source: CGNC:12233
See related: Ensembl:ENSGALG00010001896
Gene type: protein coding
RefSeq status: MODEL
Organism: Gallus gallus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 3

Exon count:: 29

Annotation release	Status	Assembly	Chr	Location
106	current	bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2)	3	NC_052534.1 (90543173..90657727, complement)
106	current	bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2)	3	NC_052575.1 (90346056..90459616, complement)

Chromosome 3 - NC_052534.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Homology

NCBI Orthologs

Orthologs from OrthoDB

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables guanyl-nucleotide exchange factor activity	IEA Inferred from Electronic Annotation more info	PubMed
enables protein binding	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in actin cytoskeleton organization	IEA Inferred from Electronic Annotation more info	PubMed
involved_in mitotic spindle assembly	IEA Inferred from Electronic Annotation more info	PubMed
involved_in positive regulation of stress fiber assembly	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in centrosome	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: rho guanine nucleotide exchange factor 10

Names: Rho guanine nucleotide exchange factor (GEF) 10

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

NC_052534.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Range

90543173..90657727 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_015284923.4 → XP_015140409.2 rho guanine nucleotide exchange factor 10 isoform X3

UniProtKB/TrEMBL

A0A8V0X7K9

Conserved Domains (2) summary

cd00160
Location:408 → 592

RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.

cl17171
Location:625 → 726

PH-like; Pleckstrin homology-like domain
XM_015284925.4 → XP_015140411.2 rho guanine nucleotide exchange factor 10 isoform X4

UniProtKB/TrEMBL

A0A8V0X422, A0A8V0X7K9

Related

ENSGALP00010002633.1, ENSGALT00010004355.1

Conserved Domains (2) summary

cd00160
Location:370 → 554

RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.

cl17171
Location:587 → 688

PH-like; Pleckstrin homology-like domain
XM_015284924.4 → XP_015140410.2 rho guanine nucleotide exchange factor 10 isoform X2

UniProtKB/TrEMBL

A0A8V0X7K9

Conserved Domains (2) summary

cd00160
Location:409 → 592

RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.

cl17171
Location:625 → 726

PH-like; Pleckstrin homology-like domain
XM_015284922.4 → XP_015140408.2 rho guanine nucleotide exchange factor 10 isoform X1

UniProtKB/TrEMBL

A0A8V0X7K9, A0A8V0XDF6

Related

ENSGALP00010002626.1, ENSGALT00010004348.1

Conserved Domains (2) summary

cd00160
Location:409 → 593

RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.

cl17171
Location:626 → 727

PH-like; Pleckstrin homology-like domain
XM_046939103.1 → XP_046795059.1 rho guanine nucleotide exchange factor 10 isoform X5
XM_001235642.7 → XP_001235643.4 rho guanine nucleotide exchange factor 10 isoform X1

UniProtKB/TrEMBL

A0A8V0X7K9, A0A8V0XDF6

Conserved Domains (2) summary

cd00160
Location:409 → 593

RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.

cl17171
Location:626 → 727

PH-like; Pleckstrin homology-like domain

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

NC_052575.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Range

90346056..90459616 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_040666898.2 → XP_040522832.1 rho guanine nucleotide exchange factor 10 isoform X3

UniProtKB/TrEMBL

A0A8V0X7K9

Conserved Domains (2) summary

cd00160
Location:408 → 592

RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.

cl17171
Location:625 → 693

PH-like; Pleckstrin homology-like domain
XM_040666899.2 → XP_040522833.1 rho guanine nucleotide exchange factor 10 isoform X4

UniProtKB/TrEMBL

A0A8V0X7K9

Conserved Domains (2) summary

cd00160
Location:370 → 554

RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.

cl17171
Location:587 → 655

PH-like; Pleckstrin homology-like domain
XM_040666897.2 → XP_040522831.1 rho guanine nucleotide exchange factor 10 isoform X2

UniProtKB/TrEMBL

A0A8V0X7K9

Conserved Domains (2) summary

cd00160
Location:409 → 592

RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.

cl17171
Location:625 → 693

PH-like; Pleckstrin homology-like domain
XM_040666895.2 → XP_040522829.1 rho guanine nucleotide exchange factor 10 isoform X1

UniProtKB/TrEMBL

A0A8V0X7K9

Conserved Domains (2) summary

cd00160
Location:409 → 593

RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.

cl17171
Location:626 → 694

PH-like; Pleckstrin homology-like domain
XM_046914547.1 → XP_046770503.1 rho guanine nucleotide exchange factor 10 isoform X5
XM_040666896.2 → XP_040522830.1 rho guanine nucleotide exchange factor 10 isoform X1

UniProtKB/TrEMBL

A0A8V0X7K9

Conserved Domains (2) summary

cd00160
Location:409 → 593

RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.

cl17171
Location:626 → 694

PH-like; Pleckstrin homology-like domain