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ACTA1 actin alpha 1, skeletal muscle [ Gallus gallus (chicken) ]

Gene ID: 421534, updated on 3-Apr-2024

Summary

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Official Symbol
ACTA1provided by CGNC
Official Full Name
actin alpha 1, skeletal muscleprovided by CGNC
Primary source
CGNC:8420
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Also known as
ACTA
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 3
Exon count:
7
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 3 NC_052534.1 (39680177..39682511, complement)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 3 NC_052575.1 (39577973..39580307, complement)

Chromosome 3 - NC_052534.1Genomic Context describing neighboring genes Neighboring gene RAB4A, member RAS oncogene family Neighboring gene centriole, cilia and spindle associated protein Neighboring gene nucleoporin 133 Neighboring gene ATP binding cassette subfamily B member 10

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The amino acid sequence of actin from chicken skeletal muscle actin and chicken gizzard smooth muscle actin. Vandekerckhove J, et al. FEBS Lett, 1979 Jun 15. PMID 456601

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Force-history dependence and cyclic mechanical reinforcement of actin filaments at the single molecular level has been reported.
    Title: Force-history dependence and cyclic mechanical reinforcement of actin filaments at the single molecular level.
  2. Additive effects of the SNP present in the ACTA1 gene were associated with breast meat, liver yield, body weight at 35 days of age; drumstick skin, drumstick and breast weights. Heritability estimates for these traits ranged from 0.24+/-0.06 to 0.45+/-0.08.
    Title: Association between ACTA1 candidate gene and performance, organs and carcass traits in broilers.
  3. These data suggest that actin bundling may improve the ability of the myosin motor system for nanotransport applications.
    Title: Transport of single cells using an actin bundle-myosin bionanomotor transport system.
  4. Studies identify three sABs with particularly useful properties to systematically probe actin dynamics.
    Title: Characterization of engineered actin binding proteins that control filament assembly and structure.
Submit: New GeneRIF Correction

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Process Evidence Code Pubs
involved_in skeletal muscle thin filament assembly IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in actin filament IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in stress fiber IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in striated muscle thin filament IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
actin, alpha skeletal muscle
Names
a-actin
alpha-actin-1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001398274.1 → NP_001385203.1  actin, alpha skeletal muscle

    Status: VALIDATED

    Source sequence(s)
    BM485636, BM485946, BU107732, BX260306
    UniProtKB/Swiss-Prot
    P68139
    Conserved Domains (1) summary
    PTZ00281
    Location:4 → 377
    PTZ00281; actin; Provisional

RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052534.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    39680177..39682511 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_046938834.1 → XP_046794790.1  actin, alpha skeletal muscle isoform X1

    UniProtKB/Swiss-Prot
    P68139

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_052575.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    39577973..39580307 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_046913905.1 → XP_046769861.1  actin, alpha skeletal muscle isoform X1

    UniProtKB/Swiss-Prot
    P68139

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_001031063.1: Suppressed sequence

    Description
    NM_001031063.1: This RefSeq was removed because currently there is insufficient support for the transcript.
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P68139.1 GenPept UniProtKB/Swiss-Prot:P68139

Gene LinkOut

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