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dcun1d2b DCN1, defective in cullin neddylation 1, domain containing 2b [ Danio rerio (zebrafish) ]

Gene ID: 415246, updated on 27-Mar-2024

Summary

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Official Symbol
dcun1d2bprovided by ZNC
Official Full Name
DCN1, defective in cullin neddylation 1, domain containing 2bprovided by ZNC
Primary source
ZFIN:ZDB-GENE-040625-171
See related
Ensembl:ENSDARG00000041592 AllianceGenome:ZFIN:ZDB-GENE-040625-171
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
dcun1d2; fj80d04; zgc:86658; wu:fj80d04
Summary
Predicted to enable cullin family protein binding activity; ubiquitin conjugating enzyme binding activity; and ubiquitin-like protein binding activity. Predicted to be involved in positive regulation of ubiquitin-protein transferase activity and protein neddylation. Predicted to be part of ubiquitin ligase complex. Orthologous to human DCUN1D2 (defective in cullin neddylation 1 domain containing 2). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 1
Exon count:
7
Annotation release Status Assembly Chr Location
106 current GRCz11 (GCF_000002035.6) 1 NC_007112.7 (208177..214921, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 1 NC_007112.6 (212998..219732, complement)

Chromosome 1 - NC_007112.7Genomic Context describing neighboring genes Neighboring gene growth hormone regulated TBC protein 1a Neighboring gene ADP-ribosylhydrolase like 1 Neighboring gene transmembrane and coiled-coil domains 3 Neighboring gene transcription factor Dp-1, b Neighboring gene G protein-coupled receptor kinase 1 a

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Chaperone-Mediated Autophagy in the Light of Evolution: Insight from Fish. Lescat L, et al. Mol Biol Evol, 2020 Oct 1. PMID 32437540
  2. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables cullin family protein binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables ubiquitin conjugating enzyme binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables ubiquitin-like protein binding IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in protein neddylation IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
part_of ubiquitin ligase complex IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
DCN1-like protein 2; DCN1-like protein 2b
Names
DCN1, defective in cullin neddylation 1, domain containing 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001002156.2 → NP_001002156.2  DCN1-like protein 2b

    Status: VALIDATED

    Source sequence(s)
    CU929326
    UniProtKB/TrEMBL
    A0A8M9P764, Q6IQR0
    Related
    ENSDARP00000060970.4, ENSDART00000060971.5
    Conserved Domains (1) summary
    pfam03556
    Location:81 → 191
    Cullin_binding; Cullin binding

RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007112.7 Reference GRCz11 Primary Assembly

    Range
    208177..214921 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_021470827.1 → XP_021326502.1  DCN1-like protein 2 isoform X1

    Conserved Domains (1) summary
    pfam03556
    Location:81 → 191
    Cullin_binding; Cullin binding
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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