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ap3m2 adaptor related protein complex 3 subunit mu 2 [ Danio rerio (zebrafish) ]

Gene ID: 415244, updated on 27-Mar-2024

Summary

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Official Symbol
ap3m2provided by ZNC
Official Full Name
adaptor related protein complex 3 subunit mu 2provided by ZNC
Primary source
ZFIN:ZDB-GENE-021022-2
See related
Ensembl:ENSDARG00000016128 AllianceGenome:ZFIN:ZDB-GENE-021022-2
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
fc15g12; zgc:86670; wu:fc15g12
Summary
Predicted to be involved in endocytosis. Predicted to act upstream of or within protein transport. Predicted to be located in Golgi apparatus and cytoplasmic vesicle membrane. Predicted to be part of clathrin adaptor complex. Predicted to be active in cytoplasmic vesicle. Orthologous to human AP3M2 (adaptor related protein complex 3 subunit mu 2). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
all
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Genomic context

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Location:
chromosome: 5
Exon count:
9
Annotation release Status Assembly Chr Location
106 current GRCz11 (GCF_000002035.6) 5 NC_007116.7 (14375108..14390445, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 5 NC_007116.6 (13874891..13890228, complement)

Chromosome 5 - NC_007116.7Genomic Context describing neighboring genes Neighboring gene neuropeptide FF receptor 1 like 2 Neighboring gene tet methylcytosine dioxygenase 3 Neighboring gene K(lysine) acetyltransferase 6A Neighboring gene si:ch211-244o22.2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Genetic characterization and in vivo image analysis of novel zebrafish Danio rerio pigment mutants. Hsu CC, et al. J Fish Biol, 2013 May. PMID 23639161
  2. Evolution of complexity in the zebrafish synapse proteome. Bayés À, et al. Nat Commun, 2017 Mar 2. PMID 28252024, Free PMC Article
  3. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by ZFIN

Process Evidence Code Pubs
involved_in endocytosis IBA
Inferred from Biological aspect of Ancestor
more info
  
acts_upstream_of_or_within intracellular protein transport IEA
Inferred from Electronic Annotation
more info
  
involved_in intracellular protein transport IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within protein transport IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within vesicle-mediated transport IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
part_of clathrin adaptor complex IEA
Inferred from Electronic Annotation
more info
  
is_active_in cytoplasmic vesicle IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
AP-3 complex subunit mu-2
Names
adaptor-related protein complex 3, mu 2 subunit

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001002154.1 → NP_001002154.1  AP-3 complex subunit mu-2

    See identical proteins and their annotated locations for NP_001002154.1

    Status: PROVISIONAL

    Source sequence(s)
    BC071355
    UniProtKB/TrEMBL
    Q6IQP9
    Related
    ENSDARP00000025072.6, ENSDART00000026120.8
    Conserved Domains (2) summary
    cd09261
    Location:165 → 418
    AP-3_Mu3B_Cterm; C-terminal domain of medium Mu3B subunit in neuron-specific adaptor protein (AP) complex AP-3
    cl02092
    Location:1 → 140
    Clat_adaptor_s; Clathrin adaptor complex small chain

RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007116.7 Reference GRCz11 Primary Assembly

    Range
    14375108..14390445 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version

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