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arpc3 actin related protein 2/3 complex, subunit 3 [ Danio rerio (zebrafish) ]

Gene ID: 415204, updated on 27-Mar-2024

Summary

Official Symbol
arpc3provided by ZNC
Official Full Name
actin related protein 2/3 complex, subunit 3provided by ZNC
Primary source
ZFIN:ZDB-GENE-040625-107
See related
Ensembl:ENSDARG00000057882 AllianceGenome:ZFIN:ZDB-GENE-040625-107
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
zgc:86828
Summary
Predicted to enable actin binding activity. Predicted to contribute to actin filament binding activity. Predicted to be involved in Arp2/3 complex-mediated actin nucleation. Predicted to act upstream of or within regulation of actin filament polymerization. Predicted to be located in cytoplasm and cytoskeleton. Predicted to be part of Arp2/3 protein complex. Orthologous to human ARPC3 (actin related protein 2/3 complex subunit 3). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
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Genomic context

Location:
chromosome: 21
Exon count:
7
Annotation release Status Assembly Chr Location
106 current GRCz11 (GCF_000002035.6) 21 NC_007132.7 (17024002..17029464)
105 previous assembly GRCz10 (GCF_000002035.5) 21 NC_007132.6 (16987366..16992828)

Chromosome 21 - NC_007132.7Genomic Context describing neighboring genes Neighboring gene VPS29 retromer complex component Neighboring gene family with sequence similarity 216 member A Neighboring gene GPN-loop GTPase 3 Neighboring gene ubiquitin-conjugating enzyme E2G 1b (UBC7 homolog, yeast) Neighboring gene ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2b

Genomic regions, transcripts, and products

Expression

  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

General gene information

Markers

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables actin binding IEA
Inferred from Electronic Annotation
more info
 
contributes_to actin filament binding IBA
Inferred from Biological aspect of Ancestor
more info
 
Process Evidence Code Pubs
involved_in Arp2/3 complex-mediated actin nucleation IBA
Inferred from Biological aspect of Ancestor
more info
 
acts_upstream_of_or_within Arp2/3 complex-mediated actin nucleation IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within regulation of actin filament polymerization IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
part_of Arp2/3 protein complex IBA
Inferred from Biological aspect of Ancestor
more info
 
part_of Arp2/3 protein complex IEA
Inferred from Electronic Annotation
more info
 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 
located_in cytoskeleton IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
actin-related protein 2/3 complex subunit 3

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001002114.1NP_001002114.1  actin-related protein 2/3 complex subunit 3

    See identical proteins and their annotated locations for NP_001002114.1

    Status: PROVISIONAL

    Source sequence(s)
    AL844518
    UniProtKB/TrEMBL
    A8E5N5, Q6ZM62
    Related
    ENSDARP00000075074.5, ENSDART00000080628.6
    Conserved Domains (1) summary
    pfam04062
    Location:1173
    P21-Arc; ARP2/3 complex ARPC3 (21 kDa) subunit

RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007132.7 Reference GRCz11 Primary Assembly

    Range
    17024002..17029464
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)