dhps deoxyhypusine synthase [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: dhpsprovided by ZNC
Official Full Name: deoxyhypusine synthaseprovided by ZNC
Primary source: ZFIN:ZDB-GENE-040426-2001
See related: Ensembl:ENSDARG00000003270 AllianceGenome:ZFIN:ZDB-GENE-040426-2001
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: zgc:56018; zgc:77325; wu:fb52g04; wu:fj48f12; zgc:111900
Summary: Predicted to enable deoxyhypusine synthase activity. Acts upstream of or within exocrine pancreas development and type B pancreatic cell development. Predicted to be active in cytoplasm. Is expressed in endoderm; intestine; liver; and pancreas. Orthologous to human DHPS (deoxyhypusine synthase). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 3

Exon count:: 10

Annotation release	Status	Assembly	Chr	Location
106	current	GRCz11 (GCF_000002035.6)	3	NC_007114.7 (13424465..13437817, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	3	NC_007114.6 (13274353..13291412, complement)

Chromosome 3 - NC_007114.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

fb52g04.x1 (e-PCR)
- UniSTS:203292

AI477382 (e-PCR)
- UniSTS:206476

fj48f12.x1 (e-PCR)
- UniSTS:188624

Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables deoxyhypusine synthase activity	IBA Inferred from Biological aspect of Ancestor more info
enables deoxyhypusine synthase activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within exocrine pancreas development	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in peptidyl-lysine modification to peptidyl-hypusine	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within type B pancreatic cell development	IMP Inferred from Mutant Phenotype more info	PubMed

Component	Evidence Code	Pubs
is_active_in cytoplasm	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: deoxyhypusine synthase

NP_998387.1

EC 2.5.1.46

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.