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h3f3a H3 histone, family 3A [ Danio rerio (zebrafish) ]

Gene ID: 406269, updated on 27-Mar-2024

Summary

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Official Symbol
h3f3aprovided by ZNC
Official Full Name
H3 histone, family 3Aprovided by ZNC
Primary source
ZFIN:ZDB-GENE-040426-1928
See related
Ensembl:ENSDARG00000020504 AllianceGenome:ZFIN:ZDB-GENE-040426-1928
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
fb58e10; zgc:56193; zgc:86731; wu:fb58e10
Summary
Part of nucleosome. Is expressed in pharyngeal arch. Orthologous to human H3-3A (H3.3 histone A). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
all
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Genomic context

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Location:
chromosome: 3
Exon count:
4
Annotation release Status Assembly Chr Location
106 current GRCz11 (GCF_000002035.6) 3 NC_007114.7 (45776370..45778122, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 3 NC_007114.6 (47824036..47825788, complement)

Chromosome 3 - NC_007114.7Genomic Context describing neighboring genes Neighboring gene G protein-coupled receptor 146 Neighboring gene G protein-coupled estrogen receptor 1 Neighboring gene unk like zinc finger Neighboring gene uncharacterized LOC101882899 Neighboring gene insulin-like growth factor binding protein, acid labile subunit

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Histone H3.3 beyond cancer: Germline mutations in Histone 3 Family 3A and 3B cause a previously unidentified neurodegenerative disorder in 46 patients. Bryant L, et al. Sci Adv, 2020 Dec. PMID 33268356, Free PMC Article
  2. Synthetic CRISPR/Cas9 reagents facilitate genome editing and homology directed repair. DiNapoli SE, et al. Nucleic Acids Res, 2020 Apr 17. PMID 32064511, Free PMC Article
  3. Oocyte-specific H2A variant H2af1o is required for cell synchrony before midblastula transition in early zebrafish embryos. Yue HM, et al. Biol Reprod, 2013 Oct. PMID 23946537
  4. Resolving Heart Regeneration by Replacement Histone Profiling. Goldman JA, et al. Dev Cell, 2017 Feb 27. PMID 28245924, Free PMC Article
  5. H3K27me3-mediated silencing of structural genes is required for zebrafish heart regeneration. Ben-Yair R, et al. Development, 2019 Oct 9. PMID 31427288, Free PMC Article

See all (12) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Clone Names

  • MGC86731, MGC165454

Gene Ontology Provided by ZFIN

Component Evidence Code Pubs
part_of nucleosome IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
H3 histone, family 3A
Names
lamprey
lpy

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_212996.1 → NP_998161.1  H3 histone, family 3A

    See identical proteins and their annotated locations for NP_998161.1

    Status: PROVISIONAL

    Source sequence(s)
    BC045982
    UniProtKB/Swiss-Prot
    Q6PI20
    Related
    ENSDARP00000120344.1, ENSDART00000146211.2
    Conserved Domains (2) summary
    PTZ00018
    Location:1 → 136
    PTZ00018; histone H3; Provisional
    pfam00125
    Location:1 → 132
    Histone; Core histone H2A/H2B/H3/H4

RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007114.7 Reference GRCz11 Primary Assembly

    Range
    45776370..45778122 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017353759.1 → XP_017209248.1  H3 histone, family 3A isoform X1

    UniProtKB/Swiss-Prot
    A5PL96, Q6PI20, Q7ZV67
    UniProtKB/TrEMBL
    B2GSF5
    Related
    ENSDARP00000154528.1, ENSDART00000192849.1
    Conserved Domains (1) summary
    PTZ00018
    Location:1 → 136
    PTZ00018; histone H3; Provisional
Nucleotide Protein
Heading Accession and Version

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