cox15 cytochrome c oxidase assembly homolog 15 (yeast) [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: cox15provided by ZNC
Official Full Name: cytochrome c oxidase assembly homolog 15 (yeast)provided by ZNC
Primary source: ZFIN:ZDB-GENE-040426-955
See related: Ensembl:ENSDARG00000075933 AllianceGenome:ZFIN:ZDB-GENE-040426-955
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: zgc:56240; zgc:77422; wu:fa18g06
Summary: Predicted to enable oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor. Predicted to be involved in heme A biosynthetic process. Predicted to be located in membrane. Predicted to be integral component of membrane. Predicted to be active in mitochondrial inner membrane. Human ortholog(s) of this gene implicated in Leigh disease; fatal infantile cardioencephalomyopathy due to cytochrome c oxidase deficiency 2; and hypertrophic cardiomyopathy. Orthologous to human COX15 (cytochrome c oxidase assembly homolog COX15). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 13

Exon count:: 9

Annotation release	Status	Assembly	Chr	Location
106	current	GRCz11 (GCF_000002035.6)	13	NC_007124.7 (713941..724386)
105	previous assembly	GRCz10 (GCF_000002035.5)	13	NC_007124.6 (583650..594095)

Chromosome 13 - NC_007124.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

fa18g06.s1 (e-PCR)
- UniSTS:202436

fd07h12.x1 (e-PCR)
- UniSTS:195028

Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor	IBA Inferred from Biological aspect of Ancestor more info
enables oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in heme A biosynthetic process	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within heme A biosynthetic process	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in membrane	IEA Inferred from Electronic Annotation more info
is_active_in mitochondrial inner membrane	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: cytochrome c oxidase assembly protein COX15 homolog

Names: COX15 homolog, cytochrome c oxidase assembly protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_201206.2 → NP_957500.2 cytochrome c oxidase assembly protein COX15 homolog

Status: VALIDATED

Source sequence(s)

EH439430, FP111012

UniProtKB/TrEMBL

A0A8M1PE82, F1R355

Related

ENSDARP00000099785.1, ENSDART00000109737.2

Conserved Domains (1) summary

pfam02628
Location:59 → 388

COX15-CtaA; Cytochrome oxidase assembly protein