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tbca tubulin cofactor a [ Danio rerio (zebrafish) ]

Gene ID: 394029, updated on 27-Mar-2024

Summary

Official Symbol
tbcaprovided by ZNC
Official Full Name
tubulin cofactor aprovided by ZNC
Primary source
ZFIN:ZDB-GENE-040426-962
See related
Ensembl:ENSDARG00000016754 AllianceGenome:ZFIN:ZDB-GENE-040426-962
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
zgc:56262
Summary
Predicted to enable tubulin binding activity. Predicted to be involved in protein folding and tubulin complex assembly. Predicted to be located in cytoplasm and microtubule. Predicted to be active in microtubule cytoskeleton. Orthologous to human TBCA (tubulin folding cofactor A). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
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Genomic context

Location:
chromosome: 21
Exon count:
4
Annotation release Status Assembly Chr Location
106 current GRCz11 (GCF_000002035.6) 21 NC_007132.7 (7545062..7570768)
105 previous assembly GRCz10 (GCF_000002035.5) 21 NC_007132.6 (7807394..7833100)

Chromosome 21 - NC_007132.7Genomic Context describing neighboring genes Neighboring gene adaptor related protein complex 3 subunit beta 1a Neighboring gene uncharacterized LOC110438212 Neighboring gene orthopedia homeobox a Neighboring gene WD repeat domain 41

Genomic regions, transcripts, and products

Expression

  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

General gene information

Markers

Clone Names

  • MGC56262

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables beta-tubulin binding IEA
Inferred from Electronic Annotation
more info
 
enables tubulin binding IBA
Inferred from Biological aspect of Ancestor
more info
 
Process Evidence Code Pubs
acts_upstream_of_or_within post-chaperonin tubulin folding pathway IEA
Inferred from Electronic Annotation
more info
 
involved_in post-chaperonin tubulin folding pathway IEA
Inferred from Electronic Annotation
more info
 
involved_in protein folding IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in tubulin complex assembly IBA
Inferred from Biological aspect of Ancestor
more info
 
acts_upstream_of_or_within tubulin complex assembly IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 
located_in cytoskeleton IEA
Inferred from Electronic Annotation
more info
 
located_in microtubule IEA
Inferred from Electronic Annotation
more info
 
is_active_in microtubule cytoskeleton IBA
Inferred from Biological aspect of Ancestor
more info
 

General protein information

Preferred Names
tubulin-specific chaperone A

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_201054.1NP_957348.1  tubulin-specific chaperone A

    See identical proteins and their annotated locations for NP_957348.1

    Status: PROVISIONAL

    Source sequence(s)
    BC046032
    UniProtKB/TrEMBL
    A0A8M1PFI7, Q7ZV25
    Related
    ENSDARP00000012019.7, ENSDART00000023997.8
    Conserved Domains (1) summary
    pfam02970
    Location:980
    TBCA; Tubulin binding cofactor A

RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007132.7 Reference GRCz11 Primary Assembly

    Range
    7545062..7570768
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)