atg13 ATG13 autophagy related 13 homolog (S. cerevisiae) [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: atg13provided by ZNC
Official Full Name: ATG13 autophagy related 13 homolog (S. cerevisiae)provided by ZNC
Primary source: ZFIN:ZDB-GENE-040426-1149
See related: Ensembl:ENSDARG00000036040 AllianceGenome:ZFIN:ZDB-GENE-040426-1149
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: zgc:63526
Summary: Predicted to be involved in mitophagy; piecemeal microautophagy of the nucleus; and protein localization to phagophore assembly site. Predicted to act upstream of or within autophagosome assembly. Predicted to be located in cytoplasm. Predicted to be part of Atg1/ULK1 kinase complex. Predicted to be active in cytosol and phagophore assembly site. Predicted to be extrinsic component of membrane. Orthologous to human ATG13 (autophagy related 13). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 7

Exon count:: 18

Annotation release	Status	Assembly	Chr	Location
106	current	GRCz11 (GCF_000002035.6)	7	NC_007118.7 (38793833..38807841, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	7	NC_007118.6 (38522575..38536585, complement)

Chromosome 7 - NC_007118.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

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General gene information

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Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables protein kinase regulator activity	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within autophagosome assembly	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within autophagy	IEA Inferred from Electronic Annotation more info
involved_in mitophagy	IBA Inferred from Biological aspect of Ancestor more info
involved_in piecemeal microautophagy of the nucleus	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within positive regulation of chondrocyte proliferation	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in protein localization to phagophore assembly site	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within regulation of autophagy	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within regulation of chondrocyte development	IMP Inferred from Mutant Phenotype more info	PubMed

Component	Evidence Code	Pubs
part_of Atg1/ULK1 kinase complex	IBA Inferred from Biological aspect of Ancestor more info
part_of Atg1/ULK1 kinase complex	IEA Inferred from Electronic Annotation more info
is_active_in autophagosome	IBA Inferred from Biological aspect of Ancestor more info
located_in cytoplasm	IEA Inferred from Electronic Annotation more info
is_active_in cytosol	IBA Inferred from Biological aspect of Ancestor more info
is_active_in phagophore assembly site	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: autophagy-related protein 13

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_200433.2 → NP_956727.1 autophagy-related protein 13

See identical proteins and their annotated locations for NP_956727.1

Status: PROVISIONAL

Source sequence(s)

BC054904

UniProtKB/Swiss-Prot

Q7SYE0

Related

ENSDARP00000052323.3, ENSDART00000052324.6

Conserved Domains (1) summary

pfam10033
Location:19 → 192

ATG13; Autophagy-related protein 13

RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

NC_007118.7 Reference GRCz11 Primary Assembly

Range

38793833..38807841 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_005168970.4 → XP_005169027.1 autophagy-related protein 13 isoform X1

UniProtKB/TrEMBL

A0A8M2BG96

Conserved Domains (1) summary

pfam10033
Location:19 → 192

ATG13; Autophagy-related protein 13