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sh2d4a SH2 domain containing 4A [ Danio rerio (zebrafish) ]

Gene ID: 393219, updated on 27-Mar-2024

Summary

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Official Symbol
sh2d4aprovided by ZNC
Official Full Name
SH2 domain containing 4Aprovided by ZNC
Primary source
ZFIN:ZDB-GENE-040426-932
See related
Ensembl:ENSDARG00000041378 AllianceGenome:ZFIN:ZDB-GENE-040426-932
Gene type
protein coding
RefSeq status
MODEL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
zgc:56186
Summary
Predicted to be active in cytoplasm. Orthologous to human SH2D4A (SH2 domain containing 4A). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
all
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Genomic context

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Location:
chromosome: 10
Exon count:
12
Annotation release Status Assembly Chr Location
106 current GRCz11 (GCF_000002035.6) 10 NC_007121.7 (6946692..6978934, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 10 NC_007121.6 (6988358..7020195, complement)

Chromosome 10 - NC_007121.7Genomic Context describing neighboring genes Neighboring gene DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 Neighboring gene solute carrier family 38 member 9 Neighboring gene pleckstrin and Sec7 domain containing 3, like Neighboring gene fucosyltransferase 10

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article
  4. Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database. Pasquier J, et al. BMC Genomics, 2016 May 18. PMID 27189481, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Clone Names

  • MGC56186

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  

General protein information

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Preferred Names
SH2 domain-containing protein 4A; SH2 domain-containing protein 4B
Names
SH2 domain-containing protein 4A-like

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007121.7 Reference GRCz11 Primary Assembly

    Range
    6946692..6978934 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005156459.4 → XP_005156516.1  SH2 domain-containing protein 4A isoform X1

    See identical proteins and their annotated locations for XP_005156516.1

    UniProtKB/TrEMBL
    A0A8M2B2I8
    Conserved Domains (1) summary
    cl15255
    Location:306 → 408
    SH2; Src homology 2 (SH2) domain

  2. XM_009305120.3 → XP_009303395.1  SH2 domain-containing protein 4A isoform X2

    UniProtKB/TrEMBL
    A0A8M3BCU5
    Conserved Domains (1) summary
    PTZ00121
    Location:30 → 243
    PTZ00121; MAEBL; Provisional

  3. XM_005156461.4 → XP_005156518.1  SH2 domain-containing protein 4B isoform X3

    UniProtKB/TrEMBL
    A0A8M2B2J2
    Related
    ENSDARP00000110829.3, ENSDART00000123312.3
    Conserved Domains (1) summary
    PTZ00121
    Location:30 → 208
    PTZ00121; MAEBL; Provisional

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_200249.1: Suppressed sequence

    Description
    NM_200249.1: This RefSeq was temporarily suppressed because it CDS was partial.
Nucleotide Protein
Heading Accession and Version

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