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Wdr95 WD40 repeat domain 95 [ Mus musculus (house mouse) ]

Gene ID: 381693, updated on 8-Feb-2024

Summary

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Official Symbol
Wdr95provided by MGI
Official Full Name
WD40 repeat domain 95provided by MGI
Primary source
MGI:MGI:1923042
See related
Ensembl:ENSMUSG00000029658 AllianceGenome:MGI:1923042
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
4930434E21Rik
Summary
Orthologous to human WDR49 (WD repeat domain 49). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Low expression observed in reference dataset See more
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Genomic context

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Location:
5 G3; 5 89.18 cM
Exon count:
32
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 5 NC_000071.7 (149407874..149535359)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 5 NC_000071.6 (149484409..149611894)

Chromosome 5 - NC_000071.7Genomic Context describing neighboring genes Neighboring gene CapStarr-seq enhancer MGSCv37_chr5:150230952-150231169 Neighboring gene mesenteric estrogen dependent adipogenesis Neighboring gene RIKEN cDNA 4933425D22 gene Neighboring gene testis expressed 26 Neighboring gene STARR-seq mESC enhancer starr_14933 Neighboring gene predicted gene 15997 Neighboring gene predicted gene, 54316 Neighboring gene STARR-seq mESC enhancer starr_14938 Neighboring gene predicted gene, 35763 Neighboring gene STARR-positive B cell enhancer ABC_E3638 Neighboring gene STARR-positive B cell enhancer ABC_E1317 Neighboring gene heat shock 105kDa/110kDa protein 1 Neighboring gene STARR-seq mESC enhancer starr_14940 Neighboring gene predicted gene, 20005 Neighboring gene NME/NM23 nucleoside diphosphate kinase, pseudogene 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. Hansen GM, et al. Genome Res, 2008 Oct. PMID 18799693, Free PMC Article
  2. Normalization and subtraction: two approaches to facilitate gene discovery. Bonaldo MF, et al. Genome Res, 1996 Sep. PMID 8889548
  3. Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Zambrowicz BP, et al. Proc Natl Acad Sci U S A, 2003 Nov 25. PMID 14610273, Free PMC Article
  4. A high-resolution anatomical atlas of the transcriptome in the mouse embryo. Diez-Roux G, et al. PLoS Biol, 2011 Jan 18. PMID 21267068, Free PMC Article
  5. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073

See all (12) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (2) 

General gene information

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Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
  

General protein information

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Preferred Names
uncharacterized protein LOC381693

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_029440.3 → NP_083716.2  uncharacterized protein LOC381693

    Status: VALIDATED

    Source sequence(s)
    AK087389, AW122438
    Consensus CDS
    CCDS39409.1
    UniProtKB/TrEMBL
    E9PUB4, Q8BN84
    Related
    ENSMUSP00000106128.2, ENSMUST00000110502.7
    Conserved Domains (4) summary
    COG2319
    Location:12 → 460
    WD40; WD40 repeat [General function prediction only]
    pfam00400
    Location:425 → 460
    WD40; WD domain, G-beta repeat
    sd00039
    Location:47 → 87
    7WD40; WD40 repeat [structural motif]
    cl02567
    Location:12 → 301
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000071.7 Reference GRCm39 C57BL/6J

    Range
    149407874..149535359
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017320945.2 → XP_017176434.1  uncharacterized protein LOC381693 isoform X1

    Conserved Domains (4) summary
    COG2319
    Location:799 → 939
    WD40; WD40 repeat [General function prediction only]
    cd00200
    Location:450 → 758
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    sd00039
    Location:462 → 498
    7WD40; WD40 repeat [structural motif]
    pfam13833
    Location:125 → 178
    EF-hand_8; EF-hand domain pair
Nucleotide Protein Strain
Heading Accession and Version

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