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CG15120 [ Drosophila melanogaster (fruit fly) ]

Gene ID: 37248, updated on 4-Apr-2024

Summary

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Official Symbol
CG15120provided by FlyBase
Primary source
FLYBASE:FBgn0034454
Locus tag
Dmel_CG15120
See related
AllianceGenome:FB:FBgn0034454
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
Dmel\CG15120
Summary
Predicted to enable chaperone binding activity; heat shock protein binding activity; and ubiquitin protein ligase binding activity. Predicted to be involved in negative regulation of cell death. Predicted to be located in cytosol and nucleus. Orthologous to human PACRG (parkin coregulated). [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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Location:
56D13-56D14; 2-89 cM
Exon count:
5
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (19497752..19500372)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (15385257..15387877)

Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene Outer segment 6 Neighboring gene Rab escort protein Neighboring gene hippo Neighboring gene uncharacterized protein Neighboring gene long non-coding RNA:CR44472 Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Identification of Drosophila mutants altering defense of and endurance to Listeria monocytogenes infection. Ayres JS, et al. Genetics, 2008 Mar. PMID 18245331, Free PMC Article
  2. Inactivation of Hippo and cJun-N-terminal Kinase (JNK) signaling mitigate FUS mediated neurodegeneration in vivo. Gogia N, et al. Neurobiol Dis, 2020 Jul. PMID 32199908, Free PMC Article
  3. Decoding cilia function: defining specialized genes required for compartmentalized cilia biogenesis. Avidor-Reiss T, et al. Cell, 2004 May 14. PMID 15137945
  4. Reproductive status alters transcriptomic response to infection in female Drosophila melanogaster. Short SM, et al. G3 (Bethesda), 2013 May 20. PMID 23550122, Free PMC Article
  5. Genes conserved in bilaterians but jointly lost with Myc during nematode evolution are enriched in cell proliferation and cell migration functions. Erives AJ. Dev Genes Evol, 2015 Sep. PMID 26173873, Free PMC Article

See all (27) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables Hsp70 protein binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables Hsp90 protein binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables ubiquitin protein ligase binding ISS
Inferred from Sequence or Structural Similarity
more info
  
Component Evidence Code Pubs
located_in cytosol ISS
Inferred from Sequence or Structural Similarity
more info
  
located_in nucleus ISS
Inferred from Sequence or Structural Similarity
more info
  

General protein information

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Preferred Names
uncharacterized protein
Names
CG15120-PA

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033778.4 Reference assembly

    Range
    19497752..19500372
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_137584.3 → NP_611428.1  uncharacterized protein Dmel_CG15120 [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_611428.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    A1ZBM4, C0HDN9
    Related
    FBpp0085659
    Conserved Domains (1) summary
    pfam10274
    Location:121 → 304
    ParcG; Parkin co-regulated protein
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
A1ZBM4 A1ZBM4
Q8MZ25 Q8MZ25

Gene LinkOut

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