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Fam76b family with sequence similarity 76, member B [ Rattus norvegicus (Norway rat) ]

Gene ID: 367021, updated on 13-Apr-2024

Summary

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Official Symbol
Fam76bprovided by RGD
Official Full Name
family with sequence similarity 76, member Bprovided by RGD
Primary source
RGD:1311077
See related
Ensembl:ENSRNOG00000024863 AllianceGenome:RGD:1311077
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
RGD1311077
Summary
Predicted to be located in nuclear speck. Orthologous to human FAM76B (family with sequence similarity 76 member B). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in Thymus (RPKM 157.9), Spleen (RPKM 118.8) and 9 other tissues See more
Orthologs
human mouse all
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Genomic context

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See Fam76b in Genome Data Viewer
Location:
8q12
Exon count:
13
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 8 NC_086026.1 (18971357..18993442)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 8 NC_051343.1 (10689396..10711847)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 8 NC_005107.4 (12355767..12378040)

Chromosome 8 - NC_086026.1Genomic Context describing neighboring genes Neighboring gene myotubularin related protein 2 Neighboring gene centrosomal protein 57 Neighboring gene uncharacterized LOC134480141 Neighboring gene uncharacterized LOC134480142 Neighboring gene uncharacterized LOC103693014

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. Genome-wide analysis of histidine repeats reveals their role in the localization of human proteins to the nuclear speckles compartment. Salichs E, et al. PLoS Genet, 2009 Mar. PMID 19266028, Free PMC Article
  2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RGD

Component Evidence Code Pubs
located_in nuclear speck ISO
Inferred from Sequence Orthology
more info
  

General protein information

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Preferred Names
protein FAM76B

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001394343.1 → NP_001381272.1  protein FAM76B isoform 1

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000008
    UniProtKB/TrEMBL
    A0A8I6GJF8
    Conserved Domains (1) summary
    pfam16046
    Location:6 → 327
    FAM76; FAM76 protein

  2. NM_001401220.1 → NP_001388149.1  protein FAM76B isoform 2

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000008
    UniProtKB/TrEMBL
    A0A8I6GG35, A6JN80
    Related
    ENSRNOP00000087548.1, ENSRNOT00000116723.1

RNA

  1. NR_172100.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000008

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086026.1 Reference GRCr8

    Range
    18971357..18993442
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006242526.3 → XP_006242588.1  protein FAM76B isoform X1

    UniProtKB/TrEMBL
    A0A8I6AI20, A0A8I6GJF8
    Related
    ENSRNOP00000092636.1
    Conserved Domains (1) summary
    pfam16046
    Location:6 → 311
    FAM76; FAM76 protein

  2. XM_006242527.3 → XP_006242589.1  protein FAM76B isoform X2

    UniProtKB/TrEMBL
    A0A8I6GJF8
    Conserved Domains (1) summary
    pfam16046
    Location:6 → 310
    FAM76; FAM76 protein

  3. XM_039081825.2 → XP_038937753.1  protein FAM76B isoform X3

    UniProtKB/TrEMBL
    A0A8I6GJF8
    Conserved Domains (1) summary
    pfam16046
    Location:6 → 311
    FAM76; FAM76 protein

  4. XM_039081826.2 → XP_038937754.1  protein FAM76B isoform X4

    UniProtKB/TrEMBL
    A0A8I6GJF8
    Conserved Domains (1) summary
    pfam16046
    Location:6 → 310
    FAM76; FAM76 protein

  5. XM_039081829.2 → XP_038937757.1  protein FAM76B isoform X7

    UniProtKB/TrEMBL
    A6JN81, D3Z8B9
    Related
    ENSRNOP00000062410.1
    Conserved Domains (1) summary
    pfam16046
    Location:6 → 147
    FAM76; FAM76 protein

  6. XM_006242531.5 → XP_006242593.1  protein FAM76B isoform X5

    Conserved Domains (1) summary
    pfam16046
    Location:145 → 266
    FAM76; FAM76 protein

  7. XM_039081827.2 → XP_038937755.1  protein FAM76B isoform X6

    Conserved Domains (1) summary
    pfam16046
    Location:101 → 222
    FAM76; FAM76 protein

RNA

  1. XR_010054004.1 RNA Sequence

  2. XR_010054005.1 RNA Sequence

  3. XR_010054003.1 RNA Sequence

Nucleotide Protein Strain
Heading Accession and Version

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