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Asb7 ankyrin repeat and SOCS box-containing 7 [ Rattus norvegicus (Norway rat) ]

Gene ID: 365277, updated on 3-Apr-2024

Summary

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Symbol
Asb7provided by RGD
Full Name
ankyrin repeat and SOCS box-containing 7provided by RGD
Primary source
RGD:1305154
See related
Ensembl:ENSRNOG00000013795 AllianceGenome:RGD:1305154
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Predicted to be involved in intracellular signal transduction and protein ubiquitination. Orthologous to human ASB7 (ankyrin repeat and SOCS box containing 7). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in Kidney (RPKM 54.7), Thymus (RPKM 44.4) and 9 other tissues See more
Orthologs
human mouse all
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Genomic context

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Location:
1q22
Exon count:
10
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 1 NC_086019.1 (129621462..129677788, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 1 NC_051336.1 (120222835..120267411, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 1 NC_005100.4 (127545671..127599257, complement)

Chromosome 1 - NC_086019.1Genomic Context describing neighboring genes Neighboring gene transfer RNA proline (anticodon AGG) 55 Neighboring gene uncharacterized LOC134485131 Neighboring gene lines homolog 1 Neighboring gene ceramide synthase 3 Neighboring gene heat shock cognate 71 kDa protein-like

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RGD

Process Evidence Code Pubs
involved_in intracellular signal transduction IEA
Inferred from Electronic Annotation
more info
  
involved_in protein ubiquitination IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
ankyrin repeat and SOCS box protein 7
Names
ankyrin repeat and SOCS box-containing protein 7

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001108915.2 → NP_001102385.1  ankyrin repeat and SOCS box protein 7

    See identical proteins and their annotated locations for NP_001102385.1

    Status: PROVISIONAL

    Source sequence(s)
    JAXUCZ010000001
    UniProtKB/TrEMBL
    A0A8I5ZQV9, A6JBQ8
    Related
    ENSRNOP00000080514.1, ENSRNOT00000095353.1
    Conserved Domains (4) summary
    PTZ00322
    Location:219 → 272
    PTZ00322; 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase; Provisional
    PHA02875
    Location:21 → 241
    PHA02875; ankyrin repeat protein; Provisional
    cd03726
    Location:273 → 317
    SOCS_ASB7; SOCS (suppressors of cytokine signaling) box of ASB7-like proteins. ASB family members have a C-terminal SOCS box and an N-terminal ankyrin-related sequence. The general function of the SOCS box is the recruitment of the ubiquitin-transferase system. The ...
    sd00045
    Location:81 → 114
    ANK; ANK repeat [structural motif]

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086019.1 Reference GRCr8

    Range
    129621462..129677788 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006229350.5 → XP_006229412.1  ankyrin repeat and SOCS box protein 7 isoform X1

    See identical proteins and their annotated locations for XP_006229412.1

    UniProtKB/TrEMBL
    A0A8I5ZQV9, A6JBQ8
    Conserved Domains (4) summary
    PTZ00322
    Location:219 → 272
    PTZ00322; 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase; Provisional
    PHA02875
    Location:21 → 241
    PHA02875; ankyrin repeat protein; Provisional
    cd03726
    Location:273 → 317
    SOCS_ASB7; SOCS (suppressors of cytokine signaling) box of ASB7-like proteins. ASB family members have a C-terminal SOCS box and an N-terminal ankyrin-related sequence. The general function of the SOCS box is the recruitment of the ubiquitin-transferase system. The ...
    sd00045
    Location:81 → 114
    ANK; ANK repeat [structural motif]

  2. XM_006229349.5 → XP_006229411.1  ankyrin repeat and SOCS box protein 7 isoform X1

    See identical proteins and their annotated locations for XP_006229411.1

    UniProtKB/TrEMBL
    A0A8I5ZQV9, A6JBQ8
    Conserved Domains (4) summary
    PTZ00322
    Location:219 → 272
    PTZ00322; 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase; Provisional
    PHA02875
    Location:21 → 241
    PHA02875; ankyrin repeat protein; Provisional
    cd03726
    Location:273 → 317
    SOCS_ASB7; SOCS (suppressors of cytokine signaling) box of ASB7-like proteins. ASB family members have a C-terminal SOCS box and an N-terminal ankyrin-related sequence. The general function of the SOCS box is the recruitment of the ubiquitin-transferase system. The ...
    sd00045
    Location:81 → 114
    ANK; ANK repeat [structural motif]

  3. XM_039085011.2 → XP_038940939.1  ankyrin repeat and SOCS box protein 7 isoform X1

    UniProtKB/TrEMBL
    A0A8I5ZQV9, A6JBQ8
    Conserved Domains (4) summary
    PTZ00322
    Location:219 → 272
    PTZ00322; 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase; Provisional
    PHA02875
    Location:21 → 241
    PHA02875; ankyrin repeat protein; Provisional
    cd03726
    Location:273 → 317
    SOCS_ASB7; SOCS (suppressors of cytokine signaling) box of ASB7-like proteins. ASB family members have a C-terminal SOCS box and an N-terminal ankyrin-related sequence. The general function of the SOCS box is the recruitment of the ubiquitin-transferase system. The ...
    sd00045
    Location:81 → 114
    ANK; ANK repeat [structural motif]

  4. XM_063269228.1 → XP_063125298.1  ankyrin repeat and SOCS box protein 7 isoform X2

    UniProtKB/TrEMBL
    D3ZVT6

  5. XM_063269231.1 → XP_063125301.1  ankyrin repeat and SOCS box protein 7 isoform X3

RNA

  1. XR_010055191.1 RNA Sequence

Nucleotide Protein Strain
Heading Accession and Version

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