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Zfp780b zinc finger protein 780B [ Mus musculus (house mouse) ]

Gene ID: 338354, updated on 30-Apr-2024

Summary

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Official Symbol
Zfp780bprovided by MGI
Official Full Name
zinc finger protein 780Bprovided by MGI
Primary source
MGI:MGI:2444764
See related
Ensembl:ENSMUSG00000063047 AllianceGenome:MGI:2444764
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
B230208L21Rik
Summary
Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Is expressed in genitourinary system. Orthologous to human ZNF780A (zinc finger protein 780A) and ZNF780B (zinc finger protein 780B). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in testis adult (RPKM 2.6), CNS E18 (RPKM 1.5) and 23 other tissues See more
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Genomic context

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See Zfp780b in Genome Data Viewer
Location:
7 A3; 7 15.97 cM
Exon count:
6
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (27658560..27678768, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (27959135..27979336, complement)

Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 53355 Neighboring gene Josephin domain containing 1, pseudogene Neighboring gene STARR-positive B cell enhancer ABC_E2231 Neighboring gene vomeronasal 1 receptor, pseudogene 87 Neighboring gene zinc finger protein 850

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Mouse brain organization revealed through direct genome-scale TF expression analysis. Gray PA, et al. Science, 2004 Dec 24. PMID 15618518
  2. GUDMAP: the genitourinary developmental molecular anatomy project. McMahon AP, et al. J Am Soc Nephrol, 2008 Apr. PMID 18287559
  3. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073
  4. High-efficiency full-length cDNA cloning. Carninci P, et al. Methods Enzymol, 1999. PMID 10349636
  5. RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer. Shibata K, et al. Genome Res, 2000 Nov. PMID 11076861, Free PMC Article

See all (11) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (3) 

General gene information

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Markers

Homology

Clone Names

  • MGC106695

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables DNA-binding transcription activator activity, RNA polymerase II-specific IBA
Inferred from Biological aspect of Ancestor
more info
  
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
zinc finger protein 780B

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001081021.2 → NP_001074490.1  zinc finger protein 780B isoform 1

    See identical proteins and their annotated locations for NP_001074490.1

    Status: VALIDATED

    Source sequence(s)
    AC139063
    Consensus CDS
    CCDS39853.1
    UniProtKB/TrEMBL
    E9Q2S6
    Related
    ENSMUSP00000146224.2, ENSMUST00000206685.2
    Conserved Domains (3) summary
    smart00349
    Location:14 → 75
    KRAB; krueppel associated box
    COG5048
    Location:197 → 605
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:425 → 445
    ZF_C2H2; C2H2 Zn finger [structural motif]

  2. NM_001419345.1 → NP_001406274.1  zinc finger protein 780B isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC139063
    UniProtKB/TrEMBL
    E9Q2S6
    Related
    ENSMUSP00000080324.8, ENSMUST00000081618.8

  3. NM_001419346.1 → NP_001406275.1  zinc finger protein 780B isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC139063
    UniProtKB/TrEMBL
    E9Q2S6

  4. NM_001419347.1 → NP_001406276.1  zinc finger protein 780B isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC139063
    UniProtKB/TrEMBL
    E9Q2S6

  5. NM_001419348.1 → NP_001406277.1  zinc finger protein 780B isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC139063
    UniProtKB/TrEMBL
    E9Q2S6

  6. NM_001419349.1 → NP_001406278.1  zinc finger protein 780B isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC139063

  7. NM_001419350.1 → NP_001406279.1  zinc finger protein 780B isoform 3

    Status: VALIDATED

    Source sequence(s)
    AC139063
    UniProtKB/TrEMBL
    Q52KI6
    Related
    ENSMUSP00000145799.2, ENSMUST00000205874.2

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000073.7 Reference GRCm39 C57BL/6J

    Range
    27658560..27678768 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_030242709.2 → XP_030098569.1  zinc finger protein 780B isoform X2

    Conserved Domains (2) summary
    COG5048
    Location:126 → 534
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:354 → 374
    ZF_C2H2; C2H2 Zn finger [structural motif]

  2. XM_030242706.2 → XP_030098566.1  zinc finger protein 780B isoform X1

    UniProtKB/TrEMBL
    E9Q2S6
    Conserved Domains (3) summary
    smart00349
    Location:14 → 75
    KRAB; krueppel associated box
    COG5048
    Location:197 → 605
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:425 → 445
    ZF_C2H2; C2H2 Zn finger [structural motif]

  3. XM_030242702.2 → XP_030098562.1  zinc finger protein 780B isoform X1

    UniProtKB/TrEMBL
    E9Q2S6
    Conserved Domains (3) summary
    smart00349
    Location:14 → 75
    KRAB; krueppel associated box
    COG5048
    Location:197 → 605
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:425 → 445
    ZF_C2H2; C2H2 Zn finger [structural motif]
Nucleotide Protein Strain
Heading Accession and Version

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