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tbl2 transducin beta like 2 [ Danio rerio (zebrafish) ]

Gene ID: 337068, updated on 27-Mar-2024

Summary

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Official Symbol
tbl2provided by ZNC
Official Full Name
transducin beta like 2provided by ZNC
Primary source
ZFIN:ZDB-GENE-030131-9012
See related
Ensembl:ENSDARG00000043357 AllianceGenome:ZFIN:ZDB-GENE-030131-9012
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
wu:fa96f08
Summary
Is expressed in yolk syncytial layer. Orthologous to human TBL2 (transducin beta like 2). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 10
Exon count:
8
Annotation release Status Assembly Chr Location
106 current GRCz11 (GCF_000002035.6) 10 NC_007121.7 (33254710..33265677, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 10 NC_007121.6 (33310854..33321817, complement)

Chromosome 10 - NC_007121.7Genomic Context describing neighboring genes Neighboring gene collagen alpha-1(XXVI) chain-like Neighboring gene BAF chromatin remodeling complex subunit BCL7B a Neighboring gene PR domain containing 15 Neighboring gene C2 calcium dependent domain containing 2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Evolution of complexity in the zebrafish synapse proteome. Bayés À, et al. Nat Commun, 2017 Mar 2. PMID 28252024, Free PMC Article
  2. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by ZFIN

Process Evidence Code Pubs
involved_in endoplasmic reticulum unfolded protein response IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in endoplasmic reticulum IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
transducin beta-like protein 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_212767.1 → NP_997932.1  transducin beta-like protein 2 precursor

    See identical proteins and their annotated locations for NP_997932.1

    Status: PROVISIONAL

    Source sequence(s)
    BC065682
    UniProtKB/TrEMBL
    Q6P0B5
    Related
    ENSDARP00000063641.4, ENSDART00000063642.6
    Conserved Domains (3) summary
    COG2319
    Location:78 → 411
    WD40; WD40 repeat [General function prediction only]
    sd00039
    Location:87 → 130
    7WD40; WD40 repeat [structural motif]
    cl02567
    Location:76 → 390
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007121.7 Reference GRCz11 Primary Assembly

    Range
    33254710..33265677 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005172641.4 → XP_005172698.1  transducin beta-like protein 2 isoform X1

    UniProtKB/TrEMBL
    A0A8M2BJZ4, E7F4J8
    Conserved Domains (3) summary
    COG2319
    Location:78 → 411
    WD40; WD40 repeat [General function prediction only]
    sd00039
    Location:87 → 130
    7WD40; WD40 repeat [structural motif]
    cl02567
    Location:76 → 390
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
Nucleotide Protein Strain
Heading Accession and Version

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