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rcan1b regulator of calcineurin 1b [ Danio rerio (zebrafish) ]

Gene ID: 336348, updated on 27-Mar-2024

Summary

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Official Symbol
rcan1bprovided by ZNC
Official Full Name
regulator of calcineurin 1bprovided by ZNC
Primary source
ZFIN:ZDB-GENE-030131-8292
See related
AllianceGenome:ZFIN:ZDB-GENE-030131-8292
Gene type
protein coding
RefSeq status
MODEL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
dscr1; rcan1; wu:fr92c05
Summary
Predicted to enable nucleic acid binding activity. Predicted to act upstream of or within calcineurin-NFAT signaling cascade. Human ortholog(s) of this gene implicated in Alzheimer's disease. Orthologous to human RCAN1 (regulator of calcineurin 1). [provided by Alliance of Genome Resources, Apr 2022]
Annotation information
Annotation category: partial on reference assembly
Orthologs
all
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Genomic context

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Location:
chromosome: Un
Exon count:
3
Annotation release Status Assembly Chr Location
106 current GRCz11 (GCF_000002035.6) Unplaced Scaffold NW_003334033.1 (12432..22011)
105 previous assembly GRCz10 (GCF_000002035.5) Unplaced Scaffold NW_003334033.1 (9626..20076)

NW_003334033.1Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Conserved role of the urotensin II receptor 4 signalling pathway to control body straightness in a tetrapod. Alejevski F, et al. Open Biol, 2021 Aug. PMID 34375549, Free PMC Article
  2. Vascular defects of DYRK1A knockouts are ameliorated by modulating calcium signaling in zebrafish. Cho HJ, et al. Dis Model Mech, 2019 May 23. PMID 31043432, Free PMC Article
  3. A comparative map of the zebrafish genome. Woods IG, et al. Genome Res, 2000 Dec. PMID 11116086, Free PMC Article
  4. The zebrafish gene map defines ancestral vertebrate chromosomes. Woods IG, et al. Genome Res, 2005 Sep. PMID 16109975, Free PMC Article
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

See all (7) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables nucleic acid binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within calcium-mediated signaling IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
calcipressin-1; LOW QUALITY PROTEIN: calcipressin-1
Names
Down syndrome critical region gene 1
regulator of calcineurin 1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NW_003334033.1 Reference GRCz11 Primary Assembly

    Range
    12432..22011
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_021470802.1 → XP_021326477.1  LOW QUALITY PROTEIN: calcipressin-1

    UniProtKB/TrEMBL
    A0A8M9P730
    Conserved Domains (1) summary
    cl17169
    Location:33 → 201
    RRM_SF; RNA recognition motif (RRM) superfamily
Nucleotide Protein Strain
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