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eef1b2 eukaryotic translation elongation factor 1 beta 2 [ Danio rerio (zebrafish) ]

Gene ID: 335370, updated on 27-Mar-2024

Summary

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Official Symbol
eef1b2provided by ZNC
Official Full Name
eukaryotic translation elongation factor 1 beta 2provided by ZNC
Primary source
ZFIN:ZDB-GENE-030131-7310
See related
Ensembl:ENSDARG00000044521 AllianceGenome:ZFIN:ZDB-GENE-030131-7310
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
fj06d02; zgc:56277; zgc:86802; wu:fj06d02
Summary
Predicted to enable guanyl-nucleotide exchange factor activity. Predicted to be involved in translational elongation. Predicted to act upstream of or within translation. Predicted to be part of eukaryotic translation elongation factor 1 complex. Predicted to be active in cytosol. Orthologous to human EEF1B2 (eukaryotic translation elongation factor 1 beta 2). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 6
Exon count:
6
Annotation release Status Assembly Chr Location
106 current GRCz11 (GCF_000002035.6) 6 NC_007117.7 (13201010..13206255, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 6 NC_007117.6 (12967475..12972720, complement)

Chromosome 6 - NC_007117.7Genomic Context describing neighboring genes Neighboring gene ADAM metallopeptidase domain 23a Neighboring gene zinc finger, DBF-type containing 2 Neighboring gene NADH:ubiquinone oxidoreductase core subunit S1 Neighboring gene INO80 complex subunit Db

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Reduced expression of the Nodal co-receptor Oep causes loss of mesendodermal competence in zebrafish. Vopalensky P, et al. Development, 2018 Mar 6. PMID 29440298
  2. Novel zebrafish caspase-3 substrates. Valencia CA, et al. Biochem Biophys Res Commun, 2007 Sep 21. PMID 17643392
  3. Bone morphogenetic protein signaling governs biliary-driven liver regeneration in zebrafish through tbx2b and id2a. Choi TY, et al. Hepatology, 2017 Nov. PMID 28599080, Free PMC Article
  4. Stimulation of glycolysis promotes cardiomyocyte proliferation after injury in adult zebrafish. Fukuda R, et al. EMBO Rep, 2020 Aug 5. PMID 32648304, Free PMC Article
  5. Repetitive Elements Trigger RIG-I-like Receptor Signaling that Regulates the Emergence of Hematopoietic Stem and Progenitor Cells. Lefkopoulos S, et al. Immunity, 2020 Nov 17. PMID 33159854

See all (13) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Clone Names

  • MGC86802

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables translation elongation factor activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within translation IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within translational elongation IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
part_of eukaryotic translation elongation factor 1 complex IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
elongation factor 1-beta

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_199949.2 → NP_956243.1  elongation factor 1-beta

    See identical proteins and their annotated locations for NP_956243.1

    Status: PROVISIONAL

    Source sequence(s)
    AY398339
    UniProtKB/TrEMBL
    Q7ZV16
    Related
    ENSDARP00000065372.4, ENSDART00000065373.5
    Conserved Domains (2) summary
    cd10308
    Location:3 → 62
    GST_C_eEF1b_like; Glutathione S-transferase C-terminal-like, alpha helical domain of eukaryotic translation Elongation Factor 1 beta
    pfam00736
    Location:142 → 225
    EF1_GNE; EF-1 guanine nucleotide exchange domain

RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007117.7 Reference GRCz11 Primary Assembly

    Range
    13201010..13206255 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

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